Multi-disciplinary Review of Optimal Seizure Management in Lennox-Gastaut Syndrome

Overview

With reference to data presented at the 58^th Annual Meeting of the Japan Epilepsy Society (JES) held in Utsunomiya, Japan, from 2^nd–4^th September 2025, and the 36^th International Epilepsy Congress (IEC) held in Lisbon, Portugal, from 30^th August–3^rd September 2025

This course is intended for healthcare professionals practicing in Cardiology.

There are 10 questions post-webinar, and these will require a pass mark of 70% or higher to collect credit.

This educational activity is free of charge.

Objectives

By the end of this activity, learners will be able to:

Describe the clinical presentation and progression of Lennox-Gastaut syndrome (LGS), focusing on symptoms and key diagnostic tools for identifying early childhood episodes, and the impact on patients and families regarding the burden of care.
Explain the various treatment options available for LGS seizure management and describe the underlying mechanisms of action that support the management of LGS.
Describe the heterogeneous nature of HCM, including the wide variety of symptoms and severities.
Analyse the guidelines and evidence for the treatment of LGS in Asian territories, such as Japan and the Middle East.
Evaluate the key takeaways and recent guidelines from events including the International Epilepsy Congress (IEC), Japan Epilepsy Society (JES) and Middle East Education to update knowledge and clinical practice.

Faculty

Professor Ley Sander

Department of Clinical and Experimental Epilepsy, University College, London Queen Square Institute of Neurology, UK, National Hospital for Neurology and Neurosurgery, London, UK

Disclosures: Sander has received research grants from UCB Pharma; honoraria or consultation fees from Angellini, Eisai, and UCB; and participated in a company sponsored speaker’s bureau for Angelini, GW, Zogenix, and Eisai. Humphry and Balestrini have declared no conflicts of interest.

Dr Simona Balestrini

Meyer Children's Hospital IRCSS, Florence, Italy, Chalfont Centre for Epilepsy, London, UK

CME

Information:

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the European Board for Accreditation of Continuing Education for Health Professionals (EBAC®) through the joint providership of Mind Hill and EMJ Learning. The European Board for Accreditation of Continuing Education for Health Professionals (EBAC) accredits Continuing Education (CE) programmes for the international medical community. Mind Hill is an EBAC accredited provider since 2023.

This activity is accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC®) for 1:00 hour of effective education time, and is designated for 1 EBAC CME Credit.

The European Board for Accreditation of Continuing Education for Health Professionals (EBAC®) holds an agreement on mutual recognition of substantive equivalency with the US Accreditation Council for CME (ACCME) and the Royal College of Physicians and Surgeons of Canada, respectively. European Board for Accreditation of Continuing Education for Health Professionals (EBAC®) holds an agreement on mutual recognition of substantive equivalency with the US Accreditation Council for Continuing Medical Education (ACCME) and the Royal College of Physicians and Surgeons of Canada. Through an agreement between EBAC® and the American Medical Association, physicians may convert EBAC® External CME credits to AMA PRA Category 1 Credits. Information on the process to convert EBAC® credit to AMA credit can be found on the AMA website. Other healthcare professionals may obtain from the AMA a certificate of having participated in an activity eligible for AMA PRA Category 1 Credit. EBAC® is a member of the International Academy for CPD Accreditation (IACPDA) and a partner member of the International Association of Medical Regulatory Authorities (IAMRA).

How to earn your CME credit:

In order to obtain your CME credit and acquire your certificate, please launch the activity and complete the interactive patient case study before completing the multiple-choice assessment.

Through an agreement between EBAC® and the American Medical Association, physicians may convert EBAC® External CME credits to AMA PRA Category 1 Credits. Information on the process to convert EBAC® credit to AMA credit can be found on the AMA website. Other healthcare professionals may obtain from the AMA a certificate of having participated in an activity eligible for conversion of credit to AMA PRA Category 1 Credit.

EBAC® is a member of the International Academy for CPD Accreditation (IACPDA) and a partner member of the International Association of Medical Regulatory Authorities (IAMRA).

Any queries, please email: [email protected]

Support

This course was supported by a continuing medical educational grant from Jazz Pharmaceuticals.