A case report explores whether mRNA COVID-19 vaccination may coincide with hematopoietic malignancy and possible mechanisms.

CXCL12, a chemokine involved in immune cell trafficking and tumour microenvironment regulation, appeared to be strongly associated with improved survival outcomes.

Autoantibody expression after paediatric stem cell transplantation reflects immune reconstitution rather than chronic graft versus host disease risk, highlighting alternative biomarkers.

A machine learning approach reveals structural HLA biomarkers linked to graft failure, offering a new strategy for donor selection in transplantation.

My journey has been a long one. I am a paediatric immunologist and principal investigator of a PID research laboratory, and this…

STEM cell therapy is emerging as a promising approach for silicosis, an irreversible fibrotic lung disease caused by chronic exposure to respirable crystalline silica.

Abnormal Wnt signalling may drive a rare, high-risk childhood liver cancer and influence chemotherapy response, new research suggests.

Early morning cord blood transplantation was shown to reduce acute graft-versus-host disease severity and improve survival.

A real-world analysis suggests outpatient stem-cell mobilisation in multiple myeloma could safely reduce hospital admissions and bed use through risk stratification and machine learning prediction.

Parvovirus B19 was shown to infect haematopoietic stem cells, impairing self renewal and differentiation, with JAK2 STAT5 inhibition partially reversing virus induced bone marrow dysfunction.

A large English registry analysis shows survival in multiple myeloma declines with each treatment line and is significantly longer in patients receiving autologous stem cell transplant.

Early haematopoietic stem cell transplantation after liver transplantation resulted in 90% survival in children with hepatitis-associated aplastic anaemia, with normal blood counts and liver function at follow up.

Interview with David Fisher, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA…

A first-in-human pilot trial suggests umbilical cord–derived mesenchymal stem cell eye drops may safely improve symptoms and inflammation in refractory dry eye, including Sjögren’s syndrome.

A new genetic classification integrating co-mutations significantly refines risk stratification in NPM1-mutated AML and may guide allogeneic transplant decisions in first complete remission.

Expert insights from Dr Hana F. Safah on treating invasive fungal infections in hematology/oncology patients…

By reconstructing a fetal liver–specific niche, FLOs enable simultaneous development of hepatic and hematopoietic lineages, revealing cross-talk essential for understanding human liver development and immune injury.

Between 2011 and 2021, 7,322 men were diagnosed with germ cell cancer in Sweden and Norway.

Inflammatory molecules circulating in the blood may worsen disease symptoms and points to new opportunities for targeted therapy.

Review paper concludes that stem cells and growth factors are effective in treating diabetic foot ulcers. But improved treatment protocols are needed before wider clinical adoption.

Scientists used a chemotherapy-free stem cell approach to reverse type 1 diabetes in mice, restoring insulin production and immune balance without long-term medication.

Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic modalities such as…