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Interview: Pier Mannuccio Mannucci
4
Mins
March 2024
I think the beginning was when I graduated in the 1960s; my thesis was on red cell enzymes within haematology, but it had nothing to do…
Read more
10
Mins
13th December 2018
Editor’s Pick: Newest Approaches in Immunotherapy for Non-Hodgkin’s Lymphoma
Immunotherapy has revolutionised the treatment of haematologic malignancies. Patients with relapsed/refractory non-Hodgkin’s lymphoma have poor response…
8
Mins
4th September 2018
Editor’s Pick: Chimeric Antigen Receptor-Engineered T Cell Therapy in Acute Myeloid Leukaemia
Acute myeloid leukaemia (AML) is a disease with a very poor outcome and remains an area of significant unmet need, necessitating novel therapeutic…
12
Mins
4th September 2018
Epstein–Barr Virus: A Biological Overview and Clinicopathological Changes of Two Epstein–Barr Virus-Related Lymphoproliferative Disorders in a World Health Organization (WHO) 2017 Report
Epstein–Barr virus (EBV) is one of the most important viral causes for the development of tumours. The global geographical epidemiology of EBV shows…
10
Mins
4th September 2018
A Game of Clones: The Complex Interplay of Aplastic Anaemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Haemoglobinuria
Although idiopathic aplastic anaemia (AA), myelodysplastic syndrome (MDS), and paroxysmal nocturnal haemoglobinuria (PNH) are all associated with…
6
Mins
2nd August 2018
Planning Your Next Move in Philadelphia Chromosome Positive Leukaemias
The meeting was arranged as a series of conversations between experts, following a question and answer format with two speakers in each presentation…
9
Mins
2nd August 2018
Editor's Pick: Allogeneic Haematopoietic Stem Cell Transplantation for Chronic Myeloid Leukaemia in the Era of Tyrosine Kinase Inhibitors
The introduction of tyrosine kinase inhibitors (TKI) has dramatically improved the prognosis of chronic myeloid leukaemia (CML) patients and, therefore…
10
Mins
2nd August 2018
Therapeutic Options in Myelodysplastic Syndromes: Established and Emerging Therapies
Although hypomethylating agents (HMA) have revolutionised the treatment of myelodysplastic syndromes (MDS), a significant proportion of patients either…
11
Mins
2nd August 2018
Making Rituximab Directly Cytotoxic for Substantial Improvement in Therapeutic Efficacy
The humanised anti-CD20 antibody (Ab) rituximab (RTX) has significantly improved the prognosis of B cell non-Hodgkin’s lymphomas (BNHL). However, major…
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