ada.enesco, Author at European Medical Journal - Page 18 of 65

Carbon Build-up in Lungs Linked to COPD Severity

Macrophages in COPD lungs show elevated carbon loads, larger cell size, and enhanced inflammation, highlighting a potential driver of disease progression.

JAK Inhibition Protects Against Immunotherapy-Driven Diabetes

In a new study, researchers identified a specific immune cell type, CD4+ T follicular helper (Tfh) cells producing IL-21 and IFN-γ, as a key driver of ICI-T1DM.

One in Three Maternal Deaths Linked to Social Services

A UK-wide study finds that women with children’s social care involvement face significantly higher maternal mortality risks, especially from psychiatric causes.

Novel Tuberculosis Drug Candidates Emerge as Safer Alternatives to Linezolid

Delpazolid and sutezolid show strong efficacy and reduced toxicity in Phase 2 TB trials, offering safer alternatives to linezolid for drug-resistant TB treatment.

New AI Model Improves Sudden Cardiac Death Prediction

MAARS uniquely integrates electronic health records, imaging reports, and contrast-enhanced cardiac MRI using a transformer-based neural network.

Re-Irradiation Shows Promise in Local Prostate Relapse

Patients treated on the entire prostate or surgical bed had better DMFS compared to those treated only on the relapse site.

Multimorbidity Score Predicts Poor Outcomes in Difficult-to-Treat Asthma

MiDAS, a new clinical tool, predicts poor outcomes in difficult asthma by scoring multimorbidity burden, highlighting the need for whole-patient care.

ADHD May Causally Increase Allergy Risk in Children

The findings provide genetic evidence supporting the theory that the nervous and immune systems may interact more closely in children with ADHD.

Dupilumab Cuts COPD Flares in Patients with Type 2 Inflammation

A post hoc analysis confirms dupilumab reduces key inflammatory biomarkers and COPD exacerbations, with highest benefit in patients with raised eosinophils and FeNO.

High Pacemaker Implantation Rates After Transcatheter Aortic Valve Implantation

Rates of permanent pacemaker implantation exceed 20% in patients with aortic regurgitation.