stevenpaul, Author at European Medical Journal - Page 20 of 37

Early Diffusion-Weighted MRI at 3 Tesla Detects Ischaemic Changes of the Optic Nerve in Anterior Ischaemic Optic Neuropathy

Anterior ischaemic optic neuropathy (AION) is the most common acute optic neuropathy in older patients. Its annual incidence is 2.3–10.2 cases per 100,000 persons over 50 years.

Diencephalic Syndrome: Anaesthetic Management and Post-Operative Complications

Diencephalic syndrome (DS), first described by Russell in 1951, is a rare cause of failure to thrive in infants and young children with preservation of linear growth.

Weight Management, Micronutrients, and Supplements in Diabetes

T2D remission (an HbA1c <48 mmol/mol without the use of glucose lowering medications for 6 months), improvements in cardiovascular risk factors, and decreased T2D-associated mortality can be achieved through sustained weight loss.

Immediate Perinatal Outcome of Mothers with Maternal Near-Miss at Moi Teaching and Referral Hospital, Eldoret, Kenya

Improving maternal health has been a major concern worldwide. This is evident by maternal health being included in the Millennium Development Goals, with the goal of reducing maternal mortality by three-quarters by 2015, and now the Sustainable Development Goals, with targets set to reduce the global maternal mortality ratio to less than 70 per 100,000 live births.

Editor's Pick: Diabetic Ketoacidosis in Pregnancy: An Overview of Pathophysiology, Management, and Pregnancy Outcomes

Diabetic ketoacidosis (DKA), characterised by the triad of acute hyperglycaemia, metabolic acidosis, and ketosis, is an acute life-threatening but preventable complication of diabetes.

EMJ Urology 10.1

Pigmentary Maculopathy in Interstitial Cystitis/Bladder Pain Syndrome Treated with Oral Pentosan Polysulfate: A Review

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition of unknown aetiology. Symptoms can vary but there is typically pelvic pain or discomfort perceived to be related to the urinary bladder, usually accompanied by other urinary symptoms such as the persistent urge to void or frequency.

EMJ Urology 10.1

Advancing Patient Care in the Evolving Prostate Cancer Treatment Landscape

Prostate cancer varies at initial diagnosis and in its progression, with non-metastatic and metastatic presentations that may or may not respond to ADT (Figure 1).

Allergy 71 Feature Image

Hereditary Angioedema Management: From Dealing to Leading

A two-part digital symposium series entitled ‘Hereditary Angioedema (HAE) Management: From Dealing to Leading,’ took place during the European Academy of Allergy and Clinical Immunology (EAACI) Hybrid Congress, held in Prague, Czechia, in July 2022.

Allergy 71 Feature Image

Establishing New Standards in Hereditary Angioedema: Improving Outcomes Through Routine Prophylaxis

Hereditary angioedema (HAE) is a rare but debilitating and potentially fatal disease that presents in various forms, and can be difficult to manage. Its underlying cause is mutations in a gene that, through its protein product, controls production of the tissue enzyme kallikrein and a peptide mediator, bradykinin. The resulting overproduction of bradykinin leads to increased vascular permeability and oedema.

EMJ Neurology 10.1 Feature Image

Implications of the First Ex Vivo Gene Therapy Approved for Treating Early-Onset Metachromatic Leukodystrophy

MLD is caused by an accumulation of sulfatides in various organs and predominantly the central nervous system (CNS). Patients have an initial period of normal development, then experience developmental delay or stagnation (Figure 1).