stevenpaul, Author at European Medical Journal - Page 21 of 37

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EMJ Neurology 10.1 Feature Image
6 Mins
9 Aug 2022

Never Too Late to Treat NMDAR Encephalitis: A Paediatric Case Report and Review of Literature

Dysfunction of N-methyl-D-aspartate receptors (NMDAR) have been proposed as the aetiology for multiple neuropsychiatric diseases. While overactivity of NMDA receptors causing excitotoxicity has been implicated in epilepsy, dementia, and stroke, low activity may produce symptoms resembling those of schizophrenia.
EMJ Neurology 10.1 Feature Image
1 Mins
9 Aug 2022

Haemodynamic Determinants of Supine Hypertension in Neurogenic Orthostatic Hypotension

Patients with classic orthostatic hypotension (cOH) suffer from an abnormally large blood pressure (BP) fall upon standing due to baroreflex dysfunction. cOH, particularly in the absence of BP-lowering drugs, often has a neurogenic cause (neurogenic orthostatic hypotension [nOH]).
7 Mins
8 Aug 2022

Value-Based Radiology: A New Focus to Optimise Impact

Doctors have always liked to believe that what they do benefits their patients. It is, after all, intrinsic to our mission to “first, do no harm.” Over the centuries, however, doctors have not always achieved this goal.
9 Mins
4 Aug 2022

Paediatric Acute-on-Chronic Liver Failure

There is growing recognition of acute-on-chronic liver failure (ACLF) as a distinct clinical syndrome that portends excessively high…
6 Mins
25 Jul 2022

Next Step in Incretin-Based Therapy: From Single to Dual Agonism

The incretin effect, an augmented prandial insulin response, is mediated mostly by the hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), which are released from the intestines after meals.
14 Jul 2022

Recommendations For Better Patient Outcomes in LDL-C Management

This EMJ podcast explores the vital topic of low-density lipoprotein cholesterol (LDL-C) management in relation to the treatment and prevention of atherosclerotic cardiovascular disease. Our host, George Cooper, is joined by Michal Vrablík.
8 Mins
14 Jul 2022

Editor’s Pick: Paediatric Scleroderma: Kids Are Not Just Little Adults

The sclerodermas are a family of autoimmune rheumatic diseases characterised by activation of the adaptive and innate immune system, genetic and vascular involvement…
9 Mins
14 Jul 2022

Type I Interferons in the Pathogenesis and Treatment of Sjögren's Syndrome: An Update

Interferons (IFN) are a class of cytokines that are produced in response to pathogenic stimuli.1 The IFN family was divided into three classes: Type I, Type II, and Type III…
11 Mins
13 Jul 2022

The Role of Molecular Pathology, Early Testing, and Informatics in the Multidisciplinary Team Approach in Cancer Care: Interviews with Two Key Opinion Leaders

This article discusses how molecular pathology fits alongside traditional anatomical pathology, and the role of molecular MDTs in the management of patients with cancer.
11 Jul 2022

The latest advances in prostate cancer research

On the final day of EAU22 in Amsterdam, experts stepped away from the action to present highlights in prostate cancer treatment from this year’s congress.
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