Uncategorised - European Medical Journal

ES-SCLC Maintenance Outcomes from IMforte Trial: ASCO 2025

First-line maintenance treatment with lurbinectedin and atezolizumab significantly improves survival outcomes in patients with extensive-stage small cell lung cancer (ES-SCLC), according to primary results from the global Phase III IMforte trial presented at ASCO 2025.

New Oral Therapy Doubles PFS in ESR1+ Breast Cancer: ASCO 2025

A NEW oral therapy may significantly delay disease progression in patients with ESR1-mutated, ER-positive, HER2-negative advanced breast cancer, according to results presented at the 2025 ASCO Annual Meeting.

Severe Pediatric Conditions Drive Hospital Resource Strain

Children with complex chronic diseases (C-CDs) and life-limiting conditions (LLCs) account for a disproportionate share of pediatric hospital admissions and resource use, according to a new retrospective study conducted in the Basque Public Health System.

Weight Loss Alters Liver Fatty Acid Metabolism Pathways

The findings support the concept that excessive lipogenesis, rather than just fat delivery from other sources, is central to MASLD development.

Pneumococcal Disease Threat Rises for Veterans Post-Flu

VETERANS hospitalized with influenza or respiratory syncytial virus (RSV) face a significantly elevated risk of secondary Streptococcus pneumoniae infection, while those with COVID-19 appear to have a reduced risk, according to a new national retrospective study spanning a decade of Veterans Affairs hospital data.

ESPID 2025: Expanded Antibiotic Policy Reduces Severe Group A Streptococcal Infections

This is the first real-world evidence that expanded prophylactic antibiotic use can reduce community transmission of iGAS.

Machine Learning Model Predicts COPD Exacerbations Using Digital Inhaler Data

Machine learning models using data from digital inhalers can successfully predict COPD exacerbations up to 5 days in advance.

Impaired IgA Immunity Predicts Bronchiolitis Obliterans Syndrome After Lung Transplant

New research suggests that early impairment in mucosal IgA immunity may contribute to the later development of bronchiolitis obliterans syndrome in lung transplant recipients.

ESPID 2025: Maternal RSV Vaccine Cuts Infant Admissions in Argentina

Preliminary surveillance data from Argentina’s national maternal RSV vaccination programme show a marked reduction in infant hospitalisations during the 2024 RSV season.

Inhaled Microplastics Linked to Cardiovascular Disease Risk

Once inhaled or ingested, these plastics can lodge in human tissues, including the lungs, blood, and even vascular tissues.