US Archives - Page 62 of 137 - European Medical Journal

Immunotherapy Removes Surgery Need in dMMR Cancers: AACR 2025

Neoadjuvant immunotherapy using PD-1 blockade has demonstrated the potential to eliminate the need for surgery in patients with early-stage mismatch repair-deficient (dMMR) cancers, according to groundbreaking data presented at the AACR Annual Meeting 2025.

Parkinson’s Gut Clues: How REM Sleep Disorder Shapes Microbiome Dynamics

In Parkinson’s disease (PD), gut microbiome imbalances and early symptoms like REM sleep behavior disorder (RBD) are increasingly recognized as clues to the condition’s origins and progression.

Oral Therapy in KRAS G12D-mutated Lung Cancer: AACR 2025

At the AACR 2025 Annual Meeting in Chicago, new data presented on the investigational agent zoldonrasib showed encouraging clinical activity in patients with non-small cell lung cancer (NSCLC) harboring the KRAS G12D mutation.

Should ICU Transfusions Be Limited? New Guidance

In critically ill adults, fresh frozen plasma (FFP) and platelet transfusions are commonly administered, but new guidance urges caution.

Lung Nodule Diagnosis Delays Tied to Demographics

Timely lung cancer diagnosis and treatment are essential for improved survival, but new research shows that patients with suspicious lung nodules continue to experience critical delays at multiple stages of care.

Uncovering Pneumonia Risks in Pregnancy: New Review Highlights Gaps

Pregnancy alters the immune system, increasing susceptibility to infections like Pneumocystis jirovecii, an opportunistic fungus known for causing severe pneumonia in immunocompromised individuals.

Growth and Hormonal Disruptions in Juvenile Arthritis

Juvenile idiopathic arthritis (JIA), the most common chronic rheumatic disease in children, may carry underrecognized risks for endocrine dysfunction, according to a new study that highlights significant growth and hormonal disturbances in this vulnerable population.

Real-World Psoriasis Study Compares Biologics by Age

Biologic therapies targeting interleukin (IL)-17 and IL-23 have transformed the treatment landscape for plaque psoriasis, but questions remain about how these therapies perform in elderly patients compared to younger adults.

Risks of Nonroutine Discharge After Spinal Metastasis Surgery

Patients undergoing spinal surgery for metastatic disease face a heightened risk of nonroutine discharge, often leading to increased healthcare costs and higher readmission rates.

Is Parkinson’s Disease Rooted in the Gut?

Parkinson’s disease (PD), a progressive neurodegenerative disorder impacting over 10 million people worldwide, is defined by the aggregation of misfolded α-synuclein (aSyn) in the substantia nigra pars compacta, leading to the hallmark motor symptoms of tremor, rigidity, and bradykinesia.