ACNE VULGARIS remains one of the most common and distressing dermatological conditions, affecting millions worldwide. Conventional acne treatment options, while often effective, can be limited by side effects, the risk of antibiotic resistance, and poor patient adherence. Recent innovations in light-based therapies have shown promise, and the seboselective 1726-nm laser for acne treatment represents an important advancement in this field.
Traditional therapies such as topical retinoids, antibiotics, and hormonal treatments aim to reduce sebum production, inflammation, and Cutibacterium acnes proliferation. However, these approaches can cause irritation, gastrointestinal upset, or even teratogenic effects. In contrast, the 1726-nm seboselective laser for acne treatment targets the sebaceous glands directly through selective photothermolysis, minimising damage to surrounding tissues and reducing the recurrence of acne lesions.
Long-Lasting Results With Advanced Acne Treatment
In a recent multicentre, prospective, open-label study, patients with moderate-to-severe acne vulgaris were treated monthly for three months using the seboselective 1726-nm laser for acne treatment. Results demonstrated significant and progressive improvement over time. The proportion of patients achieving at least a 50% reduction in inflammatory lesion count increased from 32.6% at four weeks to 91.5% at 52 weeks post-treatment. Moreover, 66.2% of participants achieved “clear” or “almost clear” Investigator’s Global Assessment (IGA) scores after one year.
Importantly, the treatment was well tolerated, with only mild and transient adverse events such as erythema and slight irritation. No cases of scarring, blistering, or pigmentary alteration were reported, even among patients with darker Fitzpatrick skin types. These findings underscore the device’s safety and suitability across diverse skin tones.
Beyond clinical efficacy, participants also reported enhanced self-confidence and satisfaction with their skin’s appearance, an especially meaningful outcome given the psychosocial burden of acne.
Overall, the seboselective 1726-nm laser for acne treatment offers a safe, durable, and targeted approach that addresses key limitations of traditional therapies, paving the way for improved long-term outcomes and quality of life for patients.
Reference
Goldberg D et al. Safe and effective acne treatment across skin types with a 1726 nm sebum-selective laser: one year data from a prospective multicenter study. J Am Acad Dermatol. 2025;DOI:10.1016/j.jaad.2025.09.077.
