Hema Now | Episode 29
In this episode of Hema Now, Diana Passaro from the Institut Cochin in Paris shares her insights into tumour dissemination and the infiltration of the central nervous system by leukaemic cells. She discusses the mechanisms that regulate cell‑cell interactions within the microenvironment and how emerging tools like spatial transcriptomics are shaping the next generation of leukaemia research.
Diana Passaro is a scientist at the Institut Cochin in Paris, France, whose research focuses on tumour dissemination, especially the infiltration of the central nervous system by leukaemic cells, a critical and still poorly understood process. Her lab is interested in exploring the mechanisms regulating cell-cell interaction in the tissue microenvironment during leukemogenesis.
Timestamps:
00:00 – Introduction
01:15 – Origin of interest
03:30 – Influences on research
05:30 – Work highlights
07:09 – Leukaemia challenges
08:50 – Cell–microenvironment interaction
11:55 – Science at the interfaces
15:20 – Cross-disciplinary work
16:50 – Tumour spread context
19:50 – Innovations and technology
21:01 – Future of research
23:31 – Final takeaways
