News

Clostridioides difficile infection (CDI) remains a pressing challenge in older adults, particularly those with comorbidities, leading to significant mortality and healthcare costs.

Multimorbidity, the presence of multiple co-existing health conditions, has emerged as a critical factor influencing survival and physical function in patients with systemic sclerosis (SSc), according to a large cohort study of 2,000 participants.

Healthcare professionals treating conditions such as peripheral neuropathy, wound ulcers, or radiation dermatitis now have fresh, evidence-based guidance on the use of photobiomodulation (PBM) therapy.

In a significant update for head and neck oncology care, new clinical insights into transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma (OPC) aim to guide U.S. physicians in tailoring treatment plans through a multidisciplinary lens.

Lewy body dementia (LBD), a complex neurodegenerative disorder, remains severely understudied in Latin America, according to a new scoping review analyzing the regional research landscape across major medical databases.

Radiologic imaging in high-risk cutaneous squamous cell carcinoma (cSCC) has proven more valuable than previously recognized, uncovering unexpected findings in nearly half of patients and prompting significant changes in treatment, according to a major retrospective study.

New research reveals that adults with rheumatoid arthritis (RA) are significantly more likely to develop sleep disorders, including insomnia, than those without the disease, a finding that raises important questions for rheumatologists and primary care providers.

Each flu season, influenza quietly inflicts a heavy toll on U.S. adults aged 18 to 64, with hospitalizations and deaths mounting, especially among older adults and those with chronic conditions.

Sexual health after breast cancer remains one of the least addressed yet deeply impactful aspects of survivorship, according to a new qualitative study that gives voice to the intimate challenges faced by women in the aftermath of treatment.

In a comprehensive new study using National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2020, researchers have identified strong links between specific lifestyle factors and the risk of stroke in U.S. adults.

Vaping prevalence among young adults in Great Britain, particularly use of disposable devices, has significantly declined following the government’s announcement of an impending ban on disposables raising questions about how policy shifts might influence U.S. vaping habits.

In the United States, statin initiation for atherosclerotic cardiovascular disease (ASCVD) prevention remains strikingly low, even among individuals with a clear clinical indication, according to a new prospective observational study.

New U.S. data analyzing 90-day outcomes after nonelective total hip arthroplasty (THA) for hip fracture reveals that male patients and those with pre-existing comorbidities face significantly higher risks of readmission and in-hospital mortality.

Opioid prescribing trends following outpatient surgery have seen a marked decline over the last decade, according to new U.S. claims data, signaling a nationwide shift in post-operative pain management across multiple surgical specialties.

In patients with branch atherosclerosis disease (BAD), early neurological deterioration (END) poses a significant threat to recovery, even in mild strokes.

Pediatric cancer care, medical tourism, and cross-border access to healthcare converge in a newly published 10-year review highlighting international families traveling to the United States for treatment of serious childhood malignancies and blood disorders.

Children with persistent asthma who received school-based therapy in Columbus, Ohio experienced marked improvements in asthma control and a sharp reduction in healthcare utilization, according to new research.

New data from the U.S.-based HERO Study shed light on an important question for hepatitis C virus (HCV) management: How effective is retreatment among people who inject drugs (PWID)?

In a randomized trial, researchers evaluated two physical therapy approaches—high-intensity laser therapy (HILT) and short-wave diathermy (SWD), each combined with exercise, for treating patients with Stage 2–3 knee osteoarthritis.

A new systematic review and meta-analysis sheds light on the evolving understanding of body dysmorphic disorder (BDD), presented in line with recent psychiatric research updates.

At the American Academy of Neurology (AAN) Annual Meeting 2025, researchers presented new data from the long-term open-label extension of the Phase II VISIONARY-MS trial, reporting imaging and physiologic findings consistent with improved neuronal function and remyelination in patients with multiple sclerosis (MS).

Electronic patient-reported outcomes (ePROs) are increasingly seen as a promising tool to improve cancer care quality, especially for patients with metastatic disease.

A fast, low-cost tuberculosis (TB) test that delivers results in under an hour from blood, saliva, or sputum samples could dramatically improve care in both well-equipped hospitals and resource-limited settings.

A new systematic review and meta-analysis sheds light on the growing role of antimicrobial stewardship programs (ASPs) in improving clinical outcomes for hospitalized adults with community-acquired pneumonia (CAP), a condition that remains a leading cause of hospitalization and antibiotic use in the United States.

In older adults with newly diagnosed late-onset rheumatoid arthritis (LORA), long-term glucocorticoid (GC) use remains persistent for a notable subset, according to a new analysis of national Medicare data spanning nearly a decade.

A new systematic review sheds light on how prehabilitation, interventions initiated before treatment, may influence long-term physical function and patient-reported outcomes in people affected by bladder cancer.

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, new late-breaking data from a Phase III clinical trial highlighted the efficacy and safety of telitacicept in patients with generalized myasthenia gravis (gMG).

In the clinical landscape of biliary tract infections, accurately predicting which patients are at risk of severe bloodstream infections (BSIs) can be lifesaving.

In patients with systemic sclerosis (SSc), the presence of calcinosis cutis, abnormal calcium deposits in the skin, may signal a deeper issue tied to osteoclastogenesis, the formation of bone-resorbing cells, according to a new study.

Oncolytic viral therapy may offer new hope for patients with nonmelanoma skin cancers and cutaneous lymphomas, according to a new systematic review of published and ongoing research.

Next-generation sequencing (NGS) for antimicrobial resistance (AMR) could revolutionize hospital infection control, according to a newly proposed global framework from a team of international infection prevention experts.

Intravenous fosphenytoin (fPHT) demonstrated rapid and significant pain relief for patients experiencing acute exacerbations of trigeminal neuralgia (TN), according to late-breaking results from the IFT Study presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego.

In the treatment of relapsed/refractory multiple myeloma, CAR T-cell therapy using idecabtagene vicleucel (ide-cel) has demonstrated encouraging results in a large real-world U.S. patient cohort, according to new data from the CIBMTR registry.

In a new quasi-experimental study aimed at improving pediatric epilepsy care, researchers have found that tele-nursing significantly reduces maternal anxiety and increases self-efficacy after hospital discharge.

Infant symptoms such as wheezing, eczema, vomiting, and diarrhea in the first year of life may serve as early indicators of childhood asthma risk, according to a new study that offers promising insights into early identification strategies for the chronic respiratory disease.

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, new data from the TRAILBLAZER-ALZ clinical trial program highlighted critical risk factors and management strategies for amyloid-related imaging abnormalities (ARIA) in patients with early symptomatic Alzheimer’s disease treated with donanemab.

A genome-wide association study (GWAS) presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego has identified 778 previously unknown genetic variants associated with migraine, shedding new light on the condition’s genetic underpinnings across racial and ethnic groups.

Healthcare professionals in the U.S. are closely watching progress in the diagnosis and management of IgG4-related periaortitis, periarteritis, and retroperitoneal fibrosis, a complex subset of IgG4-related disease (IgG4-RD) that mimics other conditions and defies simple diagnostic approaches.

In a new network meta-analysis evaluating treatments for vitiligo, researchers have identified the most effective combinations of phototherapy and topical therapies, offering clinicians fresh insights into optimizing patient outcomes.

In a multicenter prospective study, researchers found that a stool-based tuberculosis test could help detect TB in adults living with HIV, particularly among those with low CD4 counts.

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, researchers presented late-breaking data from the Inspire Study, a trial exploring spinal cord stimulation (SCS) as a holistic treatment for painful diabetic peripheral neuropathy (pDPN).

New results from the Phase III TEMPO-2 trial, presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, indicate that flexible-dose tavapadon significantly improved motor symptoms and daily functioning in adults with early Parkinson’s disease (PD), compared with placebo.

A new study on superficial basal cell carcinoma treatment decisions highlights that patient decision aids may subtly shift treatment preferences, with keywords such as superficial basal cell carcinoma, patient decision aid, non-invasive treatment, and effective decision-making underscoring the research.

In hospitalized patients with alcohol withdrawal syndrome (AWS), early addition of phenobarbital to lorazepam-based treatment significantly reduces the length of stay and the need for mechanical ventilation compared to dexmedetomidine, according to a new retrospective study conducted in a U.S. tertiary hospital.

Foam hand sanitizers are widely used in healthcare settings, but a recent study indicates their effectiveness may vary depending on the type of virus they’re targeting.

A new prospective cohort study has found that the rate of skin thickening progression in patients with systemic sclerosis (SSc), measured using the modified Rodnan skin score (mRSS), is closely correlated with the early onset of serious cardiopulmonary complications, including interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH).

At the 2025 American Academy of Neurology (AAN) Annual Meeting, researchers presented compelling new data showing a sharp increase in hospitalizations for cervical artery dissection, a potentially life-threatening cause of stroke, particularly in adults under 50.

A major phase 3 lung cancer trial investigating the TGIT-targeting immunotherapy ociperlimab has been halted after interim analysis indicated it would not meet its primary endpoint of overall survival.

The menstrual cycle significantly impacts women’s emotional decision-making and cognitive processing, according to a new EEG study examining approach-avoidance behaviors across different hormonal phases.

In a significant development for U.S. healthcare, new consensus guidelines from the Cystic Fibrosis Foundation call for a nationwide overhaul of newborn screening protocols for cystic fibrosis (CF).

The highly pathogenic avian influenza virus H5N1, commonly known as bird flu, is rapidly evolving in the United States, spreading beyond migratory birds to affect mammals and, most recently, dairy cattle.

A new study examining the long-term effects of a specific carbohydrate diet (SCD) in children with juvenile idiopathic arthritis (JIA) suggests potential benefits, particularly for individuals seeking to avoid medication escalation.

A novel combination of rhinoshave and fractional ablative CO2 laser therapy is proving to be a safe and effective approach for treating pronounced rhinophyma, offering precise contouring with minimal complications and high patient satisfaction, according to a new study.

Light-to-moderate alcohol consumption may contribute to increased amyloid beta (Aβ) deposition, a hallmark biomarker of Alzheimer’s disease, according to new findings from the ALBION study.

The rapid rise in prescriptions for GLP-1 receptor agonists, including tirzepatide (Mounjaro) and semaglutide (Ozempic; Lilly, Indianapolis, Indiana, USA), has sparked concerns about potential long-term safety risks.

For older adults undergoing lung transplantation, the decision between single lung transplantation (SLT) and bilateral lung transplantation (BLT) presents a trade-off between short-term recovery and long-term survival.

Hantavirus, a deadly rodent-borne virus responsible for hemorrhagic fever with renal syndrome (HFRS), has long posed diagnostic and prognostic challenges.

AI is making significant strides in the diagnosis and outcome prediction of vasculitides, rare inflammatory disorders that can be challenging to identify due to their diverse clinical presentations.

Biologic therapies significantly reduce the risk of major adverse cardiovascular events (MACEs) in patients with psoriasis and psoriatic arthritis (PsA), offering potential heart health benefits beyond skin and joint relief.

A chronic stroke aphasia study has revealed that significant language recovery can occur even after the initial recovery phase, providing hope for patients who might otherwise feel that recovery is no longer possible.

Transportation barriers are a significant yet often overlooked challenge for patients with multiple myeloma (MM), affecting access to timely care and overall health outcomes.

A new study using electroencephalogram (EEG) signals has uncovered fundamental differences in brain connectivity among children with obstructive sleep apnea (OSA), potentially paving the way for improved diagnostic methods.

A new study examining over 200,000 patients at a major U.S. medical center has revealed a striking connection between social vulnerability and penicillin allergy labels (PAL), raising questions about how social determinants of health influence medical records and treatment decisions.

A clinical trial has assessed whether 3D total-body photography (TBP) combined with sequential digital dermoscopy imaging (SDDI) enhances melanoma detection in high-risk patients.

Virtual reality (VR) is emerging as a powerful tool for enhancing cancer patient education, significantly improving understanding of disease and treatment, according to new research.

Neuropsychiatric symptoms are highly prevalent in sporadic Creutzfeldt-Jakob disease (sCJD), with nearly all patients exhibiting behavioral changes early in the disease course, according to a recent study.

Patients recovering from severe COVID-19 pneumonia may experience persistent lung function impairment long after hospital discharge, with new research highlighting vascular dysfunction as a key driver of long-term damage.

Respiratory syncytial virus (RSV) remains a leading cause of pediatric respiratory infections, with a new study highlighting its widespread co-infections and severe clinical outcomes in hospitalized children.

Children with juvenile idiopathic arthritis (JIA) face more than just joint pain, emerging research reveals that the condition may significantly delay puberty.

A novel high-intensity, high-frequency ultrasound device has demonstrated significant effectiveness in reducing facial acne scars, according to a new clinical study.

A study using machine learning has identified dynapenia, age-related muscle weakness, as a critical but overlooked risk factor for atherosclerotic cardiovascular disease (ASCVD), particularly in females.

Discover how SITC’s innovative strategies are transforming clinical trials to accelerate the development and approval of cancer immunotherapies, aiming for 100 new treatments in the next decade.

A groundbreaking new study is testing an AI-powered smartphone app designed to help pregnant smokers quit, leveraging social support and adaptive reinforcement learning to improve outcomes.

A new machine learning model predicts active tuberculosis in people with HIV more accurately than current tests, offering a promising tool for early intervention and preventive treatment.

Adipose-derived stem cells (ADSCs) may offer a groundbreaking new approach to treating systemic sclerosis (SSc), according to a recent study.

Blood plasma, fibrinogen, and fibrin have long been explored for their role in skin tissue engineering and dermatological treatments, with promising preclinical results—but clinical adoption remains limited.

A recent study explores the potential of school-based rebound therapy to improve chest health, motor function, and quality of life in children with neurodisability and respiratory issues.

Women experiencing housing insecurity are significantly less likely to receive routine breast cancer screening, according to a new study analyzing Medicaid beneficiaries in Pennsylvania.

A systematic review and meta-analysis has confirmed that positive airway pressure (PAP) therapy significantly reduces the risk of both all-cause and cardiovascular mortality in patients with obstructive sleep apnea (OSA).

A recent analysis of the SENSCIS and SENSCIS-ON trials has demonstrated that nintedanib effectively slows the decline in forced vital capacity (FVC) among patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

A newly published review highlights the evolution of Hepatitis C Virus (HCV) diagnostics, detailing key technological breakthroughs that have improved detection and management.

Critical gaps in outpatient ambulatory care utilization among older adults with dementia and mild cognitive impairment (MCI) have been revealed in a new study.

The widespread overuse of adrenal CT scans, revealing that more than half of these imaging studies are performed unnecessarily, has been investigated in a new study.

Incorporating almonds into the diet can significantly improve gut microbiota composition, enhance metabolic health, and reduce inflammation, according to new research.

A new systematic review highlights a significant but often overlooked complication in tuberculosis (TB) survivors—chronic pulmonary aspergillosis (CPA), a progressive fungal disease that can severely impact respiratory health.

A recent study conducted with the UK Medical Cannabis Registry evaluated the impact of cannabis-based medicinal products (CBMPs) on patients suffering from chronic pain due to hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).

Body-focused repetitive behaviors (BFRBs), including skin-picking, hair-pulling, and nail-biting, significantly impact quality of life, yet access to effective treatments remains a challenge.

A new systematic review and meta-analysis has assessed whether dual antiplatelet therapy (DAPT) offers significant benefits over single antiplatelet therapy (SAPT) for patients with minor stroke following thrombolysis.

A new post hoc analysis of the ADAURA trial highlights the role of osimertinib in detecting molecular residual disease (MRD) in resected EGFR-mutated stage IB–IIIA non-small-cell lung cancer (NSCLC).

Shared decision-making is widely recommended to improve patient-reported outcomes for those considering lung cancer screening (LCS), yet new research suggests communication may not significantly impact feelings of regret or distress.

A systematic review of 20 studies has found that deep brain stimulation of the subthalamic nucleus (STN-DBS), a widely used treatment for Parkinson’s disease (PD), may lead to unexpected gait and balance worsening in some patients.

AI is emerging as a promising tool in the diagnosis and management of vasculitides, a group of rare inflammatory disorders that pose significant diagnostic challenges.

AI and machine learning (ML) are reshaping dermatopathology by improving diagnostic accuracy, enabling predictive analytics, and optimizing workflows.

Patients recovering from lung cancer surgery may face prolonged hospital stays when wildfires strike, according to new research examining the effects of wildfire disasters on post-operative recovery.

A new randomized controlled trial has found that combining transcranial direct current stimulation (tDCS) with aerobic exercise (AE) significantly reduces cigarette cravings and consumption in chronic smokers.

A capacitive biosensor has been developed that offers real-time airborne detection of avian influenza H5N1 and E. coli, providing a rapid, sensitive tool for disease surveillance.

The psychometric properties of the Scleroderma Skin Questionnaire (SSQ), a novel patient-reported outcome (PRO) designed to assess skin disease in patients with systemic sclerosis (SSc), has been evaluated in a new study.

Respiratory syncytial virus (RSV) transmission in U.S. households was examined in a new study that showed young children are the primary drivers of infection, spreading the virus to adults and other household members.

Cognitive decline in relapsing-remitting multiple sclerosis (RRMS) can progress independently of both relapses and MRI-detected disease activity, challenging traditional methods of monitoring MS progression, according to the results of a new study.

A deep learning model offering a powerful tool for predicting how patients with advanced non-small cell lung cancer (NSCLC) will respond to immune checkpoint inhibitors (ICIs), potentially improving treatment personalization, has been newly developed.

A 12-month interim analysis of the AGILE Phase III open-label extension study confirms that twice-yearly depemokimab, an ultra-long-acting anti-IL-5 biologic, maintains a favorable safety and efficacy profile in patients with type 2 asthma.

Analysis of over 1.5 million U.S. adults in a new study has found that annual COVID-19 variant-targeted boosters provide meaningful protection against severe disease but lose effectiveness beyond 6 months.

A recent long-term population study from Western Australia has revealed critical insights into the relationship between rheumatoid arthritis (RA) and cancer outcomes.

Dietary recommendations for psoriasis on Instagram have been analyzed in a new study, which found that nearly all posts lack scientific credibility, with most advice coming from unqualified individuals.

A phase II trial evaluating the combination of pembrolizumab and bevacizumab in patients with untreated melanoma brain metastases (MBM) has demonstrated substantial clinical activity and promising survival outcomes.

A machine-learning classifier designed to assist healthcare professionals in accurately diagnosing the causes of transient loss of consciousness (TLOC) has been introduced in a new study.

Continuous positive airway pressure (CPAP) therapy is a cornerstone in managing severe obstructive sleep apnea (OSA) in children.

A machine learning-based model has demonstrated the ability to predict active tuberculosis (TB) in people with HIV (PWH) using clinical data, offering a promising tool for improving early detection and preventive treatment.

New data from a 15-year study presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco reveals significant disparities in latent tuberculosis infection (LTBI) testing practices within the United States.

A recent study presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco has unveiled a simplified approach to assessing antiretroviral therapy (ART) adherence among pregnant women living with HIV in Malawi.

A recent phase 3 open-label extension study has demonstrated that delgocitinib cream is both safe and effective for long-term management of chronic hand eczema (CHE) in adults.

A recent analysis from the RESOLVE-1 trial has highlighted the potential of mycophenolate mofetil (MMF) in treating diffuse cutaneous systemic sclerosis (dcSSc), particularly in early-stage disease.

A new systematic review and meta-analysis of over 1.3 million patients has confirmed that remdesivir significantly improves survival rates for hospitalized COVID-19 patients, yet treatment guidelines may not fully reflect this evolving evidence.

Increasing diversity in research, from basic science to clinical trials, remains essential for advancing equitable healthcare outcomes.

Financial challenges faced by family surrogate decision-makers of stroke patients were highlighted in a new study that revealed that nearly half experience moderate to severe concerns about affording stroke-related medical expenses.

In a pivotal development for the oncology community, a recent retrospective study has demonstrated that continuing immunotherapy beyond disease progression offers significant survival benefits for patients with advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).

For decades, researchers believed that alveoli, the tiny air sacs responsible for gas exchange, formed by airspace subdivision via ingrowing septa.

Achieving comprehensive education in skin of colour (SoC) dermatology remains a challenge in residency programs, with significant disparities in exposure to diverse skin tones across institutions.

Patients with severe alopecia areata (AA) may experience prolonged hair regrowth even after discontinuing treatment with bempikibart, according to findings from the SIGNAL-AA phase 2a study presented at the American Academy of Dermatology (AAD) Annual Meeting.

Cytomegalovirus (CMV) plays a significant role in stillbirths and childhood deaths in low- and middle-income countries (LMICs), according to the results of a new study.

A phase 2 clinical trial has demonstrated that a once-daily oral tyrosine kinase 2 (TYK2) inhibitor significantly improves symptoms in adults with moderate to severe plaque psoriasis, achieving high clearance rates with a safety profile comparable to placebo.

A new analysis of five clinical trials confirms that dupilumab significantly improves lichenification in patients with moderate to severe atopic dermatitis (AD) across all ages and racial backgrounds.

A significant association between smoking and the occurrence of cryptogenic ischemic strokes (CIS) in young adults has been published in a new study.

A recent study reveals a modest increase in early palliative care (PC) billing among Medicare beneficiaries diagnosed with distant-stage cancers from 2010 to 2019.

A state-of-the-art review emphasizes the critical role of data and trust in enhancing healthcare for transgender and gender-diverse (TGD) patients.

Inflammation is increasingly recognized as a pivotal factor in the development of atherosclerosis and its associated thrombotic complications.

The importance of addressing environmental exposures, social determinants of health, and risk-taking behaviors in managing childhood asthma was emphasized in a recently published study by authors from University of Colorado School of Medicine and Children’s Hospital Colorado.

A recent global study found significant improvements in health-related quality of life (HQoL) among individuals with Hepatitis C (HCV) treated with direct-acting antivirals (DAAs) under a minimal monitoring (MINMON) approach.

Artificial intelligence (AI) is becoming a key tool in skin cancer diagnosis, but patient acceptance remains a critical aspect of its implementation.

New findings presented at the ACTRIMS Forum 2025 highlight how the latest revisions to the McDonald Criteria could reshape the diagnosis of multiple sclerosis (MS), allowing for earlier identification in patients with radiologically isolated syndrome (RIS) and atypical clinical presentations.

At the ACTRIMS Forum 2025 in West Palm Beach, Florida, researchers unveiled compelling findings on the effects of a 6-month modified Atkins diet (MAD), a less restrictive form of the ketogenic diet, on patients with relapsing multiple sclerosis (MS).

A new analysis of Phase III clinical trial data presented at the ACTRIMS Forum 2025 in West Palm Beach, Florida, suggests that tolebrutinib, a Bruton’s tyrosine kinase inhibitor (BTKi), may be effective in multiple sclerosis (MS) with chronic active lesions.

Researchers found that insomnia symptoms significantly contribute to patient-reported excessive daytime sleepiness (EDS) in a recent study examining obstructive sleep apnea (OSA).

In Southeastern Michigan, Black men face disproportionately higher mortality rates from prostate cancer, often presenting with more advanced disease stages.

Norovirus outbreaks may soon be easier to detect thanks to a novel approach combining Google search trends and wastewater surveillance.

A recent study has revealed that adult survivors of childhood cancer face a significantly elevated risk of developing melanoma, underscoring the necessity for vigilant long-term monitoring and tailored preventive strategies.

A troubling trend showing female physicians in the United States are dying by suicide at significantly higher rates than their counterparts in the general population has been exposed in a recent cohort study.

A recent cohort study has highlighted significant disparities in comorbidity profiles among patients undergoing low-dose computed tomography (LDCT) for lung cancer screening.

Smoking menthol-flavored cigarettes is associated with higher mortality risks compared to non-menthol cigarettes according to a new study.

The significant concern of Epstein-Barr virus (EBV) in pediatric liver transplant recipients due to its strong association with post-transplant lymphoproliferative disorder (PTLD) has been explored in a recently published study.

Explore the efficacy and safety of first-line targeted synthetic DMARDs in rheumatoid arthritis patients with chronic kidney disease, highlighting potential risks like deep vein thrombosis.

A recent global retrospective cohort study has demonstrated that dupilumab, a monoclonal antibody used to treat atopic dermatitis (AD), offers a favorable cardiometabolic safety profile compared to traditional systemic agents such as methotrexate and cyclosporine.

Patients with Parkinson’s disease (PD) are five times more likely to experience chronic pain than their age-matched peers, according to a new study analyzing electronic medical records from over 250 million patients.

Integrative sleep medicine is revolutionizing cancer care, as highlighted at the 21st Annual Miami Cancer Meeting (MCM) in Tampa, Florida, this January.

A novel lipid nanoparticle (LNP)-mRNA vaccine has demonstrated strong immune responses and enhanced protection against Mycobacterium tuberculosis, the leading cause of infectious mortality worldwide.

The U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for Zabalafin Hydrogel, a novel therapy designed to treat mild to moderate atopic dermatitis (AD) comprehensively.

Concerns about the effectiveness of multiple MMR vaccine booster doses in individuals who remain seronegative after the standard two-dose schedule have been highlighted in a new study.

A newly identified group of neurons in the brainstem helps regulate meal size by tracking food intake and signaling when to stop eating, according to a study published earlier this month.

Early-onset breast cancer incidence in the U.S. is rising, but new research suggests the increase is not uniform across all states. A recent study analyzing trends from 2001 to 2020 found that breast cancer rates in women under 40 have increased significantly in 21 states, with distinct regional differences.

A recent systematic review and meta-analysis has identified several effective and cost-efficient strategies to enhance measles vaccination coverage and timeliness in low-income and middle-income countries (LMICs).

Pulmonary fibrosis (PF), a severe form of lung disease, often leads to irreversible lung damage, and macrophages play a critical role in its progression.

Gastroesophageal (GE) symptoms, such as acid reflux and heartburn, are significantly associated with higher disease activity in patients with rheumatoid arthritis (RA), according to a new study.

Long-term data reveal that bimekizumab, a dual IL-17A and IL-17F inhibitor, provides sustained symptom control for patients with hidradenitis suppurativa (HS).

High-frequency oscillations (HFOs) as potential biomarkers in Alzheimer’s disease (AD), have been highlighted in a new study, offering insight into how epilepsy affects neurodegeneration.

A long-term study of assisted reproductive technology (ART) has found no increased risk of endometrial cancer, addressing concerns about the potential long-term effects of fertility treatments.

Clinical practice guidelines providing critical recommendations for managing central airway obstruction (CAO), a condition linked to poor prognosis in both malignant and nonmalignant airway diseases, have recently been published.

For patients with rheumatoid arthritis (RA) with an inadequate response to Janus kinase inhibitors (JAKi), new research suggests that cycling to another JAKi may be more effective than switching to a biologic disease-modifying anti-rheumatic drug (bDMARD).

A recent meta-analysis suggests that statin use is associated with improved survival outcomes in patients with cancer undergoing immune checkpoint inhibitor (ICI) therapy.

The U.S. Food and Drug Administration (FDA) has accepted a New Drug Application (NDA) for the first-ever twice-yearly injectable HIV prevention therapy.

A new treatment combination has emerged for patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who are ineligible for autologous stem cell transplant (ASCT).

Almond consumption and gut health may be linked and demonstrate the role of the microbiome in cardiometabolic health, according to a recent review.

A new study explores the evolution of tuberculosis isolation, from early misconceptions to modern airborne transmission guidelines. See how TB control measures have changed.

Cardiac implantable electronic device infections (CIEDIs) pose significant challenges in diagnosis and management for healthcare professionals.

A recently published review examined the impact of obesity, diabetes, and smoking on surgical outcomes for patients with hidradenitis suppurativa (HS).

Engaging in mentally stimulating activities in midlife and late life is linked to a lower risk of Alzheimer’s disease (AD), according to a study from the Chicago Health and Aging Project.

18F-FDG PET and PET/CT scans show strong diagnostic accuracy in detecting histological transformations (HT) in indolent lymphomas, including Richter’s transformation (RT) in chronic lymphocytic leukemia (CLL), according to a new meta-analysis.

A real-world study from the Netherlands has shared the benefits of lumacaftor/ivacaftor (lum/iva) in children with cystic fibrosis (CF) homozygous for the F508del mutation.

A recent study evaluated the advantages and limitations of various noninvasive imaging modalities in diagnosing cardiovascular disease (CVD) in patients with autoimmune rheumatic diseases (ARDs).

Recent advancements in artificial intelligence (AI) are reshaping dermatology, particularly in diagnosing skin diseases like skin cancer.

Emerging research highlights critical windows of susceptibility to lead exposure that may reduce antibody responses to childhood vaccines, raising concerns for immune health.

A machine learning model, SCORPIO, has shown promise in predicting the success of immune checkpoint inhibitors (ICIs) for patients with cancer.

A new randomized clinical trial suggests that once-weekly semaglutide may help reduce alcohol consumption and cravings in adults with alcohol use disorder (AUD).

The National Institutes of Health (NIH) faces substantial funding cuts that could derail progress in critical medical research.

Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) may significantly reduce the risk of chronic obstructive pulmonary disease (COPD) exacerbations in patients with type 2 diabetes (T2D), according to a large U.S.-based study.

Antibiotic-resistant Escherichia coli and Klebsiella pneumoniae are major causes of urinary tract infections (UTIs) and vaginal inflammation, posing a growing health challenge worldwide.

Survivors of blood or marrow transplants (BMT) face a significantly higher risk of developing cutaneous malignant neoplasms, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma, according to a recent cohort study.

A recent prospective cohort study highlights the incidence and clinical course of abemaciclib-induced interstitial lung disease (ILD) in patients with hormone receptor-positive (HR+), HER2-negative metastatic breast cancer (MBC) previously treated with chemotherapy.

A groundbreaking study has confirmed the presence of microplastics and nanoplastics (MNPs) in human brain tissue, raising concerns about the long-term health impact of these environmental contaminants.

Five distinct long-term exposure profiles for the use of disinfectants and cleaning products (DCPs) and their potential association with asthma has been identified in new research.

The University of Pennsylvania Health System has revealed that targeted educational interventions can significantly enhance healthcare workers’ understanding and management of regulated medical waste (RMW) in a recent study.

A recent cross-sectional study conducted at a quaternary hospital in Brazil has provided new insights into joint involvement in Sjögren’s disease (SjD), challenging its traditional classification as a non-erosive condition.

A new study has found that diet may play a key role in survival for women diagnosed with early-stage ovarian cancer.

A new review highlights how artificial intelligence (AI) and structural MRI (sMRI) are transforming early diagnosis of Autism Spectrum Disorder (ASD), offering hope for earlier interventions and improved outcomes.

The Los Angeles County wildfires in January 2025 had a notable impact on healthcare utilization, with emergency department (ED) visits decreasing by 9% while wildfire-associated visits spiked eightfold.

A systematic review and meta-analysis examining risk factors associated with Mpox infection has provided important insights into transmission patterns and protective factors.

Adults with serious mental illness (SMI) living in New York City are dying significantly younger than their peers, according to a new study.

The power of explainable artificial intelligence (xAI) combined with multimodal real-world data (RWD) to improve cancer prognosis across multiple cancer types was explored in a new study.

A new analysis of psychedelic-assisted psychotherapy (PAP) research calls for greater methodological rigor and ethical reflection as the field continues to evolve.

The potential of high-content imaging as a game-changer for precision medicine in rheumatoid arthritis (RA) has been highlighted in a new study.

Recent research into monkeypox (mpox) highlights critical gaps in vaccination coverage and infectious disease preparedness, raising concerns about future outbreaks.

A new treatment for limited-stage small cell lung cancer (LS-SCLC) has been recommended for approval in the European Union following positive results from a Phase III trial.

AI is playing an increasingly vital role in the dissemination of medical guidelines, especially in critical areas such as cardiopulmonary resuscitation (CPR).

Podcasts are emerging as an innovative solution for patient education, according to an abstract presented at the International Stroke Conference held in Los Angeles, California, USA.

In the battle against lung cancer, a recent editorial examines the effectiveness of risk prediction models in determining screening eligibility.

A novel autoimmune meningoencephalomyelitis associated with autoantibodies targeting the astrocytic intermediate filament protein vimentin has been identified in a recent case series.

The association between invasive mechanical ventilation (IMV) and an increased risk of acute kidney injury (AKI) in critically ill patients, with a notable impact on those diagnosed with COVID-19, has been investigated in a recent multicenter study.

A review article highlights the urgent need for healthcare professionals, particularly those in infectious diseases, to take action in reducing the sector’s substantial environmental impact.

A new retrospective study has shed light on the incidence of cutaneous pyogenic granulomas (PGs) by age, sex, and anatomical location.

Apixaban has been shown to reduce the risk of nonlacunar covert infarcts in patients who have experienced a recent cryptogenic stroke and have atrial cardiopathy.

Lung cancer remains one of the deadliest diseases worldwide, with changing risk factors influencing mortality rates.

Pain in adults with cystic fibrosis (CF) has long been underrecognized, and a new study reveals troubling insights into its prevalence and management.

Over 141,000 nonhospitalized U.S. veterans were included in a new study that has provided new insights into the relative severity and long-term mortality associated with SARS-CoV-2, influenza, and respiratory syncytial virus (RSV).

A ketogenic diet (KD) may worsen osteoarthritis (OA) severity and increase pain sensitivity according to the results of a new study.

Understanding why some patients with melanoma respond to immunotherapy while others do not has remained a critical challenge for precision medicine.

A recent multicenter Phase II trial has demonstrated that combining chemoradiotherapy (CRT) with aggressive local consolidative therapy (LCT) can improve survival rates in patients with Stage IV non-small cell lung carcinoma (NSCLC) presenting with oligometastases.

Kansas is grappling with a significant tuberculosis (TB) outbreak, reporting 67 active cases, 60 in Wyandotte County and seven in Johnson County, and 79 confirmed latent TB infections, predominantly in Wyandotte County.

A recent cohort study has identified a novel cortical biomarker signature that accurately predicts individual pain sensitivity, offering promising implications for the diagnosis, prevention, and treatment of chronic pain.

A recent prospective matched cohort study has revealed that individuals living with HIV (PWH) face a significantly higher risk of developing subclinical coronary atherosclerosis compared to the general population.

Risks of autoimmune conditions (ACs) in patients treated with immune checkpoint inhibitors (ICIs), a critical class of cancer immunotherapies, have been explored in a new epidemiological study.

A recent clinical trial has shown promising results in treating severe, active vitiligo through a combination of oral medication and phototherapy, offering new hope for managing this challenging condition.

A Phase II trial examining neoadjuvant therapy for difficult-to-resect cutaneous basal cell carcinoma (BCC) demonstrates promising outcomes.

In Nueces County, Texas, researchers uncovered troubling insights into dementia diagnosis awareness among a diverse population.

Financial barriers to asthma medications continue to compromise patient outcomes, increasing the risk of asthma attacks and emergency room visits, according to a recent analysis spanning 2011 to 2022.

Females are at significantly higher risk of developing long COVID compared to males, according to a recent cohort study involving over 12,000 participants.

Fixed-combination topical therapies show improvements in acne within the first 4 weeks of treatment, according to new data compiled from pivotal clinical trials.

New research published highlights a potential link between anti-inflammatory treatments and a reduced risk of Parkinson’s disease (PD) in patients with autoimmune disorders.

Immune checkpoint inhibitors, widely used in cancer therapy, have revolutionized oncology but come with the risk of severe immune-related adverse events, including checkpoint myocarditis.

Discover how a polygenic risk score enhances traditional methods for identifying undiagnosed COPD in at-risk populations, offering a significant step forward in diagnosis.

The incidence of serious head and neck infections (HNI) among children in the United States has surged dramatically since 2021, according to a new study.

A recent randomized clinical trial has demonstrated that incorporating healthy lifestyle care into chronic low back pain management can provide small but meaningful improvements in disability, weight loss, and quality of life.

A groundbreaking clinical trial has provided valuable insights into the management of dermatoporosis, a condition characterized by chronic extracellular matrix (ECM) degradation leading to skin atrophy and fragility.

Researchers at Vanderbilt University Medical Center, the University of Michigan Medical School, and the Translational Genomics Research Institute (TGen) have made significant strides in understanding idiopathic pulmonary fibrosis (IPF), an incurable and progressive lung disease.

A groundbreaking study has revealed that white button mushrooms (WBM) may reduce immune suppression and enhance anti-cancer immune responses in patients with prostate cancer.

A recent clinical trial sheds light on how interruptive clinical decision support (CDS) systems can significantly enhance suicide risk assessments in healthcare settings.

Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS), a severe inflammatory condition linked to COVID-19, has shown decreasing severity over successive pandemic waves, according to new data from Germany.

A genetic link between air pollution exposure and the risk of developing autoimmune diseases such as rheumatoid arthritis (RA), lupus, and psoriasis, has been identified in a new study.

A recent large-scale study published in a dermatology journal provides important insights into the cardiovascular safety of biologic therapies for patients with psoriasis or psoriatic arthritis (PsA).

AN increased risk of developing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following SARS-CoV-2 infection has been highlighted in a new U.S. study.

Colorectal cancer (CRC) screening guidelines may need to be more tailored, according to new research that identifies optimal stopping ages for screening based on sex, comorbidity status, and prior screening history.

New research highlights a critical yet often overlooked connection: poor sleep quality significantly increases the risk of malnutrition among adolescents with cystic fibrosis (CF).

Frailty, a dynamic and clinically significant condition, is prevalent among patients with systemic sclerosis (SSc), according to a recently published study.

In the era of tenofovir-based antiretroviral therapy (ART), HBV-coinfected people with HIV (PWH) remain at significant risk for hepatitis D virus (HDV) superinfection and liver-related mortality, according to a recent study spanning 12 years.

The U.S. Food and Drug Administration (FDA) approved a novel combination therapy for adults with KRAS G12C-mutated metastatic colorectal cancer (mCRC).

Higher consumption of red meat, particularly processed varieties, is associated with an increased risk of dementia and cognitive decline, according to a comprehensive new study.

A recent cohort study analyzing RSV protection in infants born between October 2023 and March 2024 provides critical insights into uptake patterns of maternal vaccination and monoclonal antibody therapy.

COVID-19 infection during pregnancy may modestly increase the risk of developing gestational diabetes mellitus (GDM), a recent retrospective cohort study reveals.

The way patients and clinicians prioritize different aspects of psoriatic arthritis (PsA) has been revealed in a new study that shed light on important disparities that could impact care quality and outcomes.

A new systematic review has shed light on the safety of beta blockers for treating PHACE syndrome, addressing concerns about stroke risk in patients with cerebrovascular and cardiovascular anomalies.

A new study has unveiled a groundbreaking cancer treatment approach using engineered extracellular vesicles to target both tumor cells and immunosuppressive stromal cells in the tumor microenvironment (TME).

Neurosarcoidosis, a rare and complex inflammatory disorder of the nervous system, presents unique challenges for diagnosis and treatment due to its variability and limited research.

A systematic review and meta-analysis evaluating antiviral medications for nonsevere influenza provides new insights into the optimal treatments for symptom relief and hospitalization risks, particularly for high-risk patients.

Cases of human metapneumovirus (HMPV), a common respiratory virus, are surging in parts of Asia, including China, Malaysia, India, and Kazakhstan.

A diagnostic model has been developed for primary Sjögren’s disease (pSjD), utilizing salivary biomarkers, serum autoantibodies, and Schirmer’s test.

A recent study has highlighted metformin’s potential role in reducing the risk of non-melanoma skin cancers (NMSC), offering intriguing possibilities for dermatological and oncological care.

A recent observational study has shown that AI can significantly enhance breast cancer detection rates in mammography screening without increasing unnecessary recalls.

New clinical practice guidelines for tuberculosis (TB) treatment have been released, reflecting recent clinical trial data.

In 2021, traumatic brain injuries (TBIs) claimed 69,473 lives across the United States, with significant disparities in mortality rates tied to age, race, and geographic location.

A new study reveals that patients with cutaneous lupus erythematosus (CLE) face significantly higher risks of atherosclerotic cardiovascular disease (ASCVD) compared to the general population.

Vulvovaginal candidiasis (VVC), a common condition caused by Candida albicans, affects millions of women annually and often resists standard antifungal treatments.

Post-transplant care has demonstrated that collaboration between hematopoietic cell transplantation (HCT) specialists and local oncologists can safely enhance patient outcomes while reducing caregiver burdens in a recently published research article.

Los Angeles healthcare professionals face a growing crisis as wildfire smoke engulfs the region, posing severe health risks for millions.

A new cohort study reveals that doxycycline postexposure prophylaxis (DoxyPEP) significantly reduces rates of bacterial sexually transmitted infections (STIs) among individuals using HIV preexposure prophylaxis (PrEP).

A new, cost-effective method for diagnosing isolated REM sleep behavior disorder (iRBD) using 2D cameras and advanced computer vision algorithms has been explored in a new study.

A recent study has uncovered promising advancements in the fight against Stage II melanoma by introducing a novel biomarker technique, immune Förster resonance energy transfer (iFRET).

Achieving medication-free remission (MFR) is a critical milestone in the treatment of juvenile dermatomyositis (JDM), a rare inflammatory disease primarily affecting skin and muscles.

A newly published systematic review and meta-analysis underscores the enduring benefits of endovascular thrombectomy (EVT) for patients with acute ischemic stroke caused by large vessel occlusion.

A Phase III clinical trial, ECHELON-3, has demonstrated survival benefits for patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) using a combination therapy of brentuximab vedotin (BV), lenalidomide (Len), and rituximab (R).

The growing health crisis posed by wildfire smoke, even from thousands of miles away, was made clear in a recently published study.

An epidemiological study has shed light on the primary risk factors driving Merkel cell carcinoma (MCC), a rare but aggressive form of skin cancer.

Botulinum toxin (BTX), widely known for its cosmetic and neurological applications, is emerging as a potential treatment for Raynaud’s phenomenon (RP), particularly when secondary to scleroderma.

Spinal implant infections (SIIs) are a severe complication of instrumented spinal fusion surgeries, posing significant challenges for both diagnosis and management.

A connection between lung health and kidney function in adults with cystic fibrosis (CF), identifying early urinary markers of kidney injury that correlate with neutrophil activation and reduced lung capacity, has been revealed in a new study.

Significant advancements in tailoring salvage therapy for pediatric patients with relapsed or refractory classic Hodgkin lymphoma (cHL) have been revealed in a recent clinical trial.

CRITICAL questions about the utility of PIRA and RAW as outcome measures in clinical trials for RRMS have been investigated in recently published research.

A recent cohort study highlighted a link between COVID-19 infection and accelerated kidney function decline, surpassing declines observed after other respiratory infections like pneumonia.

Native Americans experience the highest premature mortality rates from rheumatoid arthritis (RA) in the United States, according to a comprehensive study analyzing national data from 1999 to 2020.

New research links neuroimaging metrics with motor recovery in stroke patients receiving vagus nerve stimulation therapy.

A recent study has unveiled a mechanism by which estrogen receptor-positive (ER+) breast cancer cells become more aggressive after spreading to the bone marrow.

Significant gaps in the knowledge and attitudes of healthcare providers and females with epilepsy regarding reproductive health and pregnancy have been exposed in a new study.

NEW data from the 2023 National Health Interview Survey reveal that 8.4% of adults in the U.S. have experienced post-COVID-19 condition.

COPD and preserved ratio impaired spirometry (PRISm) have been identified as key accelerators of frailty progression in older adults in a new study.

Patients with moderate-to-severe atopic dermatitis who did not initially meet response criteria for lebrikizumab at 16 weeks can still achieve improvements with continued therapy, according to a recent clinical trial analysis.

A recent Phase I clinical trial has provided promising results for a novel immunotherapy approach to treat early-stage ERBB2-positive breast cancer.

The consistent effectiveness of influenza vaccines in protecting children from severe flu-related illnesses has been highlighted in recently published findings.

A recently published systematic review has shed light on chemotherapy-related cognitive impairment (CRCI) and its association with changes in brain connectivity and function.

TNF inhibitors reduce fracture risk in axial spondyloarthritis, offering protection against complications from chronic inflammation.

The VISIBLE trial sets a benchmark for diversity in psoriasis research, achieving rapid enrollment and valuable data for patients with skin of color.

Patients from disadvantaged neighborhoods are less likely to follow guidelines for pulmonary nodule care, highlighting socioeconomic disparities in healthcare access.

A recent study has revealed an alarming rise in multidrug-resistant Shigella sonnei in Vancouver, Canada among people experiencing homelessness.

Long-term trial finds neural stem cell transplants safe and shows neurological gains in spinal cord injury patients.