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Interview: Niamh O'Connell
5
Mins
April 2024
When I was a medical student in the small university city of Cork, in Ireland, there was one female consultant, and she was a haematologist…
Read more
10
Mins
27th July 2021
Von Willebrand Factor and ADAMTS13 in COVID-19 and Beyond
von Willebrand factor (VWF) is a large, adhesive, multimeric protein involved in haemostasis. The larger the size (or number of VWF multimers), the greater the functionality of the protein.
11
Mins
27th July 2021
Management of Multiple Myeloma in Older Patients
Multiple myeloma is a haematological malignancy predominantly affecting older people and has a median age of onset of 70 years.
10
Mins
27th July 2021
Current and Future Therapies for β-Thalassaemia: A Review Article
β-thalassaemias are a clinically heterogenous group of inherited disorders caused by >200 described mutations in the β-globin gene, leading to a decreased or absent production of the β-globin chain.
5
Mins
27th July 2021
Recurrent Episodes of Angioedema Consistent with Polycythaemia Vera
Polycythaemia vera (PV) is a condition characterised by an increasing number of the red blood cells in the blood.
4
Mins
27th July 2021
Glanzmann Thrombasthenia: A Case Report
Eduard Glanzmann first reported Glanzmann thrombasthenia (GT) in 1918 after he identified a functional abnormality of platelets with defective clot retraction.
9
Mins
23rd June 2021
FLT3 Mutations in Patients with Acute Myeloid Leukaemia: The Importance of Identification and Monitoring for Prognostic Determination and the Selection of Optimal Treatment Strategies
Mutations in FLT3 are the most common genetic alteration in AML. Patients with a FLT3 internal tandem duplication (ITD) mutation subtype have poor prognosis, especially when there is a high allelic burden.
9
Mins
17th June 2021
Pre-transplant Determinants of Outcome in Patients with Myeloma
Multiple myeloma is a malignant neoplasm arising from clonal proliferation of plasma cells in the bone marrow…
9
Mins
17th June 2021
New Therapeutic Approaches for Acute Myeloid Leukaemia
Acute myeloid leukaemia (AML) is a life-threatening, multifactorial haematological neoplasm characterised by the accumulation of transformed immature myeloid progenitors…
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