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Flagship Journal
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Liver Elastography for Methotrexate-Induced Fibrosis
6
Mins
March 2024
Methotrexate (MTX), an antimetabolite, has a multifarious mechanism of action that most notably includes folate antagonism, effects on…
Read more
8
Mins
31st May 2018
Acute Fatty Liver of Pregnancy: Better Understanding of Pathogenesis and Earlier Clinical Recognition Results in Improved Maternal Outcomes
Acute fatty liver of pregnancy (AFLP) is an uncommon disorder affecting women in late pregnancy. It is increasingly recognised as an important cause of…
9
Mins
31st May 2018
Targeting the Relaxin Pathway for Liver Disease Treatment
Hepatic fibrosis is a progressive disease with few treatment options outside of transplantation. Relaxin is a member of the insulin/relaxin superfamily…
9
Mins
31st May 2018
Thermal Ablation of Liver Tumours: How the Scenario Has Changed in the Last Decade
Surgical resection has long been considered the gold standard for the local treatment of primary and secondary liver tumours. Until recent years…
4
Mins
31st May 2018
Percutaneous Laser Thermal Ablation in a Patient with 22 Liver Metastases from Pancreatic Neuroendocrine Tumours: A Case Report
The relatively indolent nature of well-differentiated neuroendocrine tumours (NET) and their proclivity to be hormonally active warrants aggressive…
10
Mins
31st May 2018
Macrophages in Nonalcoholic Steatohepatitis: Friend or Foe?
Nonalcoholic steatohepatitis (NASH) is a subtype of nonalcoholic fatty liver disease that is characterised by steatosis, chronic inflammation, and…
8
Mins
30th November 2017
Hepatopulmonary Syndrome: Oxidative Stress and Physical Exercise
Hepatopulmonary syndrome (HPS) may be defined by hepatic disease, gas exchange abnormalities that may lead to hypoxaemia, and the presence of pulmonary…
14
Mins
30th November 2017
Pathogenesis, Diagnostics, and Treatment of Hereditary Haemochromatosis: A 150 Year-Long Understanding of an Iron Overload Disorder
Haemochromatosis is an iron overload disorder that can be inherited or acquired and when diagnosis is delayed, disease progression and death can occur…
10
Mins
8th June 2017
A Discussion on the Management of Wilson Disease
Prof Peter Ferenci opened the meeting by providing a background to Wilson disease (WD), an enigmatic condition where no two cases are the same. He explored…
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