European Archives - European Medical Journal

MHRA launches UK-wide gene therapy consultation

The MHRA has launched a consultation calling to update the legal definition of gene therapy medicinal products.

Gut Microbiota Biomarkers in Diabetes with Heart Disease - EMJ

Gut Microbiota Biomarkers Identified in Diabetes with Heart Disease

Researchers identified distinct gut microbiota and metabolomic signatures associated with type 2 diabetes mellitus and coronary atherosclerotic heart disease.

Tofacitinib Supports Growth in JIA - EMJ

Tofacitinib Supports Growth in Juvenile Idiopathic Arthritis

Long-term tofacitinib treatment in juvenile idiopathic arthritis was associated with normal growth and stable hormone biomarkers.

Lentigo Maligna Progression Risk Remains Low - EMJ

Lentigo Maligna Shows Low Risk of Progression to Melanoma

English registry data show lentigo maligna has only a 1% risk of progression to invasive melanoma over 10 years.

Air Pollution and Brain Health Study - EMJ

Air Pollution Linked to Poorer Brain Health

Researchers have found that air pollution exposure is associated with lower cognitive performance and signs of vascular brain injury.

Rare Cancer MALDI Imaging Study - EMJ

MALDI Imaging Advances Rare Ampullary Cancer Diagnosis

Researchers found that matrix assisted laser desorption ionisation imaging combined with machine learning may improve diagnosis and prognostic assessment in rare ampullary cancer.

Liver Disease Stigma Scale Validated in ALD Study - EMJ

New Liver Disease Stigma Scale Validated in Study

Researchers validate the Liver Disease Stigma Scale, showing higher stigma in alcohol-associated liver disease compared with non-ALD cases.

Cytomegalovirus Screening and Valacyclovir Use Rises - EMJ

Cytomegalovirus Screening Rises After Valacyclovir Trial

CMV screening and antenatal valacyclovir use increased in France after a pivotal 2020 trial, without a rise in pregnancy termination rates.

From Avoidance to Tolerance: Interview with Jennifer Koplin

One of the things that most excites me is the possibility that in the next 5–10 years, we might start to see large reductions in the number…

Orforglipron Pill Sustains Weight Loss After Injection Discontinuation

Orforglipron pills could offer a new option for stabilising weight changes after injectable GLP-1 therapy, according to the ATTAIN-MAINTAIN trial.