European Archives - Page 1126 of 1158 - European Medical Journal

Extracellular Matrix Remodelling In COPD

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that involves major remodelling of cells and tissue in the lung.

Sequential Androgen Receptor Pathway Inhibitor in Prostate Cancer: Piling-Up The Benefits or a Case for Cross-Resistance?

In the last 10 years, there has been accumulating evidence that, even in a low serum testosterone environment, the androgen receptor (AR) remains the…

Unmet Medical Needs in Non-Small-Cell Lung Cancer Treatment: How to Design Pre-Emptive Combination Therapies

The rapidly expanding catalogue of human oncogenic mutations, coupled with difficulties in identifying the cellular targets of active compounds in…

Women and Lung Cancer: Literature Assumptions and News from Recent Publications

For a long period of time, lung cancer (LC) was considered as a malignancy affecting only males, but epidemiological data have shown a dramatic increase…

Rituximab and Other New Anti-CD20 MAbs for Non-Hodgkin’s Lymphoma Treatment

Non-Hodgkin’s lymphomas (NHLs) are a heterogeneous group of different haematological cancers with a wide range of aggressiveness. NHLs represent >80% of….

Fundamental Principles of Raising an Antitumour Immune Response in Vivo: A Complex Model, a Case Report, and a Perspective

In preclinical model systems, the fundamental principles underlying a successful and durable anti-tumour immune response are well demonstrated.

Immunotherapy of Cancer: Towards a New Era

In the past two decades, immunotherapy of cancer has developed into an established treatment option. At first, the development of monoclonal antibodies…

Radiotherapy for Breast Cancer: How Can it Benefit from Advancing Technology?

There have been significant technological and technical advances in radiotherapy over the last 20 years. This paper presents the pertinent advances and…

Management of Patients with High-Grade Glioma

The scientific basis for the surgical management of patients with glioma is rapidly evolving. The infiltrative nature of these cancers precludes a…

State-Of-The-Art Treatment in Castration-Resistant Prostate Cancer

Prostate cancer (PrCa) is the most common cancer type in men in developed countries. In the last few years, a dramatic change has occurred in the…