European Archives - Page 1396 of 1424 - European Medical Journal

Premature Heart Attacks: Bad Lifestyle, Bad Luck, or Bad Genes?

Homozygous familial hypercholesterolaemia (HoFH), a rare inherited lipid disorder usually caused by bi-allelic defects in the LDLR gene, is characterised…

Imaging During Transcatheter Interventions for Valvular Heart Disease

Valvular heart disease is a growing field, and the number of new approaches for percutaneous treatment is increasing rapidly. These procedures usually…

Red Cell Distribution Width for Predicting Cardiovascular Disease: A Literature Review

Although the classical risk factors for cardiovascular disease (CVD) are very important, identification of potential novel risk factors could help…

Case Report: Double Orifice Mitral Valve with Cleft in Anterior Leaflet of Dominant Valve in an Afro-Caribbean

Double orifice mitral valve (DOMV) is a rare congenital mitral valve (MV) disorder. It is associated with other types of congenital heart disease in 45%…

The Quest for a Medical Treatment of Aortic Stenosis: Putative Therapeutic Targets

Aortic stenosis (AS), i.e. calcification and obstruction of the aortic valve (AV), is the most common type of valvular heart disease. The therapeutic…

Factors Affecting Serum Paraoxonase 1 Activity in Migrant and Resident Gujarati South Asians

Paraoxonase 1 (PON1) protects against the development of atherosclerosis by hydrolysing damaging lipid peroxides formed in low-density lipoprotein (LDL)…

Rationale for Promising Novel Therapeutic Approach Focused On Endothelin Pathway for Peripheral Arterial Disease

There is evidence to suggest that endothelin (ET-1) is involved in the pathophysiology of peripheral arterial disease (PAD), contributing to…

Current Controversies in Infective Endocarditis

Infective endocarditis (IE) remains a devastating disease with a high mortality. Its microbiology is changing with increasing incidence of Staphylococcus…

EMJ Cardiology 2014

The field of cardiology is a rapidly growing and developing one. Thanks to the progress which has been made within this area, the burden of…

EMJ

Zydelig® (idelalisib): The Force to Fight CLL and FL

After the European Commission granted the marketing authorisation for Gilead’s Zydelig® (idelalisib), a first-in-class oral treatment for chronic…