European Archives - Page 501 of 1165 - European Medical Journal

Neratinib as a Potential Therapeutic for Mutant RAS and Osimertinib-Resistant Tumours

Neratinib was developed as an irreversible catalytic inhibitor of ERBB2, which also acts to inhibit ERBB1 and ERBB4. Neratinib is U.S. Food and Drug Administration (FDA)-approved as a neo-adjuvant therapy for use in HER2+ breast cancer.

The Journey to Drug Development

This week, Joubert Gama joins our EMJ Podcast host, Jonathan Sackier to discuss innovations in pharmaceutical sciences and drug developments.

EMJ Cardiology 10 [Supplement 6] 2022

This article discussed cigarette smoking as a major risk factor for cardiovascular disease (CVD). Looking through the lens of toxic cigarette smoke constituents, the review described the oxidative stress and inflammatory responses induced following their entry into the bloodstream.

Heated Tobacco Products and Cardiovascular Disease: A Narrative Review of Peer-Reviewed Publications

This article discussed cigarette smoking as a major risk factor for cardiovascular disease (CVD). Looking through the lens of toxic cigarette smoke constituents, the review described the oxidative stress and inflammatory responses induced following their entry into the bloodstream.

Pharmacovigilance past, present and future

Marc and Helena are joined by Pav Rishiraj, Director and Head of Pharmacovigilance, Ipsen, to shed light on this often-overlooked field.

Elevating pharma’s parental leave policies

With continued drive for equality across the pharma industry, the issue of parental leave is coming to the fore. But is the industry’s approach sufficiently transparent, and what more can be done?

Five Years of World Atopic Dermatitis Day

This podcast mini-series, celebrating World Atopic Dermatitis Day 2022, explores the impact of the global awareness day, looking at how far we have come since its inception 5 years ago.

Innovations in Oncology

This week, EMJ podcast host Jonathan Sackier is joined by Sir Michael Brady, discussing his work in oncological innovations. Listen now!

World AD Day: Progress in patient care and beyond

This video, featuring Professor Stephan Weidinger, celebrates the progress made in the way diseases such as atopic dermatitis are managed via the topic of patient care transformation, as well as the importance of inspiring action to maintain the momentum needed to continue to advance towards multidisciplinary care.

Efficacy and Safety of Aficamten in Patients with Symptomatic Obstructive Hypertrophic Cardiomyopathy

Highlighting a presentation that took place as part of the European Society of Cardiology’s (ESC) Heart Failure 2022 congress, this article summarised data on the efficacy and safety of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM).