European Archives - Page 542 of 1196 - European Medical Journal

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11 Mins
11 Aug 2022

Editor's Pick: JAK Inhibitors in Rheumatoid Arthritis

JAK inhibitors (JAKi) are targeted, small-molecule, disease-modifying therapies that are the newest class of treatments to emerge for the management of rheumatoid arthritis (RA) and the first oral disease-modifying anti-rheumatic drugs (DMARD) to demonstrate comparable clinical efficacy to biological DMARDs (bDMARD).
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1 Mins
11 Aug 2022

Injection-Site Reactions Post-mRNA COVID-19 Vaccination

Early studies have reported delayed injection-site reactions in up to 0.8% of individuals receiving Moderna messenger RNA (mRNA) vaccine. These are believed to be benign and do not contraindicate subsequent doses.
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11 Mins
11 Aug 2022

Changing the Way Babies Eat: Supporting Early Allergen Feeding Around the World

This symposium occurred during the European Academy of Allergy and Clinical Immunology (EAACI) Congress, 2022.
8 Mins
11 Aug 2022

Central Role of Mast Cells in Associated Disorders

Mast cells are the central cells in the pathogenesis of many conditions that are associated with mediator release. New information is emerging about the role of mast cells in a number of conditions. This review summarises current knowledge on the topic.
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13 Mins
11 Aug 2022

Hereditary Angioedema Management: From Dealing to Leading

A two-part digital symposium series entitled ‘Hereditary Angioedema (HAE) Management: From Dealing to Leading,’ took place during the European Academy of Allergy and Clinical Immunology (EAACI) Hybrid Congress, held in Prague, Czechia, in July 2022.
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2 Mins
11 Aug 2022

Epinephrine Auto-Injector Prescription and Use: A Retrospective Analysis and Clinical Risk Assessment of Adult Patients Sensitised to Lipid Transfer Protein

Lipid transfer proteins (LTPs) are allergens widespread in plant foods. They represent the main cause of food allergy in adults living in the Mediterranean Basin.1,2 The manifestation and severity of LTP hypersensitivity are extremely variable.
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7 Mins
11 Aug 2022

Establishing New Standards in Hereditary Angioedema: Improving Outcomes Through Routine Prophylaxis

Hereditary angioedema (HAE) is a rare but debilitating and potentially fatal disease that presents in various forms, and can be difficult to manage. Its underlying cause is mutations in a gene that, through its protein product, controls production of the tissue enzyme kallikrein and a peptide mediator, bradykinin. The resulting overproduction of bradykinin leads to increased vascular permeability and oedema.
5 Mins
11 Aug 2022

Frequent Use of Moist Wipes During COVID-19: Allergic Sensitisations

During the COVID-19 pandemic, frequent handwashing and disinfection have exacerbated or caused skin diseases. This case report shows the simultaneous development of allergic contact dermatitis to Kathon CG (DuPoint, Wilmington, Delaware, USA), Euxyl K400, and fragrance mix I because of the frequent use of moist (baby) wipes during the pandemic outbreak.
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2 Mins
11 Aug 2022

Berotralstat for the Prophylaxis of Hereditary Angioedema: Outcomes in a Large Regional Immunology Centre in the UK

Hereditary angioedema (HAE) is a rare and potentially life-threatening genetic condition, whereby patients present with recurrent episodes of swelling. This affects the subcutaneous and submucosal tissues of the skin as well as mucous membranes such as the respiratory and gastrointestinal tracts.
1 Mins
9 Aug 2022

Huntingtin as a Presymptomatic Regulator of Alzheimer’s Disease

The identification of pathological elements that drive disease progression, so-called regulators, is essential when studying progressive diseases.
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