Nephrotoxic Mechanisms of Gadolinium: Implications for the Use of Gadolinium-Based Contrast Agents
Gadolinium-based contrast agents are widely used for MRI. Although they may be considered well-tolerated at recommended dosing levels, recent evidence supports the deposition of free gadolinium in the tissues and its slow release into circulation, resulting in long-term toxicity, which is aggravated in renal patients.
