Cardiology

For >20 years, clinical trials have consistently demonstrated that the reduction of levels of low-density lipoprotein (LDL) cholesterol results in lower cardiovascular event rates, in both the primary and secondary prevention setting…

Despite the respiratory tract being the most affected system, many other organs may be involved in Covid-19, including the cardiovascular system

Catheter ablation is a well-established, safe, and effective treatment option for patients with atrial fibrillation (AF) and ventricular tachycardia (VT)…

Cardiac arrest during surgery is rare but is one of the most dreaded complications, particularly when there is no obvious underlying cause or risk…

HF is a global problem, with an estimated 63 million patients worldwide living with the disease.4 It is projected that the lifetime risk of developing…

Heart failure affects up to 26 million adults worldwide.1 The overall economic cost of heart failure in 2012 was estimated to be $108 billion per annum…

As leaders in the science of pulmonary arterial hypertension (PAH), Actelion (a Janssen Pharmaceutical Company of Johnson & Johnson) sponsored a key…

Atherosclerosis is an inflammatory disease and inflammation is crucial to all stages of atherogenesis. Targeting inflammation has the potential to reduce…

AF can increase stroke risk and is generally treated with OAC therapy, such as with a VKA or a direct OAC (DOAC). However, what if someone with AF…

PAH is a rare, progressive disorder with a number of aetiologies. Approximately 15–60 patients per million of the global population are affected…

Vascular calcification is an independent risk factor for cardiovascular disease (CVD). Calcium deposits in coronary arteries can weaken vasomotor…

Hypertrophic cardiomyopathy (HCM) is a progressive primary myocardial disorder characterised by unexplained left ventricular…

Pulmonary hypertension as a cause of right-sided heart failure and shock is often missed. In the intensive care patient population…

Cardiovascular diseases complicate approximately 0.2–4.0% of pregnancies.1 Their incidence is increasing…

Researchers that individually randomised controlled trials (iRCT) assume that the observed outcomes of participants…

This study aimed to investigate the role of ECG in pre-eclampsia diagnostics and simple clinical parameters in pre-eclampsia patients with and without…

Cardiac procedures and operations following pneumonectomy present with serious challenges, both surgical and anaesthetic…

An angiographic guidewire is a basic, yet key piece of equipment in the interventional cardiologist’s armamentarium. The complications associated…

This symposium brought together experts in cardiology, nephrology, diabetology, and clinical pharmacology to discuss best practice when caring for…

New guidelines for the diagnosis and management of chronic coronary syndromes (CCS)1 were released during the 2019 European Society of Cardiology (ESC) Congress.

Based on genetic evidence, it is now known that triglyceride-rich lipoproteins lead to atherosclerosis and local inflammation, which can result in…

Cardiac amyloidosis is a rare but life-threatening group of disorders caused by the extracellular deposition of misfolded amyloid fibrils in cardiac tissue.

The authors present a brief overview on the current role of cardiac rehabilitation among HF patients in a contemporary setting and discuss some areas of…

In this review, the authors present and discuss the scientific and clinical evidence pertaining to the role of Lp(a) in calcific aortic valve stenosis.

Atrial fibrillation (AF), the most common form of arrhythmia, increases the risk of heart failure, stroke, and death. Management of AF focusses on…

Atrial fibrillation (AF), the most common form of arrhythmia, is characterised by an irregular and often fast heart rhythm resulting in uncoordinated…

In the last two decades, the interest in tricuspid valve (TV) treatment has increased;1,2 nevertheless, there is still a large percentage…

In the late 20th century, lipid lowering medications appeared to be the answer for coronary heart disease. However, despite reductions in mortality…

A contemporary conceptual framework that was proposed to distinguish between different chronic heart failure (HF) patients has highlighted varying…

Pump failure and sudden cardiac death are the leading causes of death in heart failure patients; sudden cardiac death accounts for 30–50% of deaths…

The importance of inflammation and thrombosis in the pathophysiology of atherosclerosis was debated in the 19th century by two prominent pathologists…

Prof Masana presented evidence that low-density lipoprotein (LDL) cholesterol is a causal factor for atherosclerosis and that cardiovascular disease (CVD…

Andexanet alfa is a modified factor Xa (FXa) drug designed to bind and sequester FXa inhibitors and thus reverse anticoagulation…

For >50 years, coronary angiography has been the gold standard for the assessment of coronary anatomy; however, as an isolated technique to guide the…

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. Myocardial injury in acute MI is due to both ischaemic as well…

Due to recent advances in antineoplastic treatment for breast cancer, cancer-related mortality has substantially decreased. However, several systemic…

Anaemia is a significant challenge in global health; it is characterised by lower than normal levels of red blood cells and haemoglobin per unit volume…

Chronic Chagasic cardiomyopathy (CCC) is one of the principal challenges for clinicians treating asymptomatic Chagasic patients. Only benznidazole (BZ)…

Coronary chronic total occlusions (CTO), in spite of excellent progress in the field of medicine, remain a great challenge for interventional cardiologists.

Since its introduction, the success of percutaneous transluminal coronary angioplasty (PTCA) has been jeopardised by recoil, neointima proliferation, and…

This 20 minutes didactic procedure concerns a 64 years old male presenting with anterior wall proven ischemia with diffuse coronary multivessels disease…

Cardiac disease often impacts cancer therapy, from direct toxicity of cancer therapeutic agents to the coronary endothelium, the myocardium, heart valves…

Second-generation drug-eluting stents are currently considered the standard of care in patients undergoing treatment for coronary artery disease…

Ischaemic mitral prolapse (IMP) is a pathologic entity encountered in about one-third of patients undergoing surgery for ischaemic mitral regurgitation.

Cardiac diseases have complex molecular origins. However, current clinical diagnostic tools are often inadequate to uncover specific molecular components…

Acute coronary syndrome (ACS) encompasses a spectrum of clinical disorders of myocardial ischaemia or infarction, with atherosclerosis leading to…

Premature atrial and ventricular contractions, or ectopic beats, are frequently detected on routine electrocardiogram monitoring.

Arrhythmogenic cardiomyopathy (ACM) affects mainly young athletes <35 years old and has a potential risk of malignant arrhythmias and sudden death.