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10 Mins
6 Sep 2019

A Clinical Review of Ventricular Arrhythmias in Patients with Congestive Heart Failure

Pump failure and sudden cardiac death are the leading causes of death in heart failure patients; sudden cardiac death accounts for 30–50% of deaths…
9 Mins
14 Mar 2019

Inflammation and Thrombosis in Coronary Atherosclerosis: Pathophysiologic Mechanisms and Clinical Correlations

The importance of inflammation and thrombosis in the pathophysiology of atherosclerosis was debated in the 19th century by two prominent pathologists…
10 Mins
11 Oct 2018

Guidelines, Clinical Evidence, and Real-Life Practice: How to Find Your Way in Managing Hypercholesterolaemia

Prof Masana presented evidence that low-density lipoprotein (LDL) cholesterol is a causal factor for atherosclerosis and that cardiovascular disease (CVD…
4 Mins
11 Oct 2018

Reversal of Apixaban and Rivaroxaban Anticoagulation by Andexanet Alfa in ANNEXA-A and ANNEXA-R as Assessed by Non-Tissue Factor-Initiated Thrombin Generation Independent of Tissue Factor Pathway Inhibitor

Andexanet alfa is a modified factor Xa (FXa) drug designed to bind and sequester FXa inhibitors and thus reverse anticoagulation…
10 Mins
11 Oct 2018

Editor’s Pick: Contemporary Use of Intracoronary Imaging in Percutaneous Coronary Intervention

For >50 years, coronary angiography has been the gold standard for the assessment of coronary anatomy; however, as an isolated technique to guide the…
8 Mins
11 Oct 2018

A Comparison of Different Doses of Dexmedetomidine for Myocardial Protection in Percutaneous Coronary Interventional Patients

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. Myocardial injury in acute MI is due to both ischaemic as well…
10 Mins
11 Oct 2018

Cardioprotective Approaches to the Management of Patients with Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Do We Need Increased Surveillance in Elderly Women on Trastuzumab?

Due to recent advances in antineoplastic treatment for breast cancer, cancer-related mortality has substantially decreased. However, several systemic…
7 Mins
11 Oct 2018

The Cardiomyopathy of Iron Deficiency Anaemia

Anaemia is a significant challenge in global health; it is characterised by lower than normal levels of red blood cells and haemoglobin per unit volume…
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