Flagship Journal

Vasculogenic female sexual dysfunction syndromes affect millions of ageing women worldwide, whose day-to-day symptoms of coital…

This study investigates the impact of extracapillary proliferation in proliferative lupus nephritis on remission rates in patients.

This article reviews real-world data presented at the ADA Scientific Sessions 2024. It demonstrates the glycaemic range when Control-IQ Technology users do not manually bolus for extended periods

I have worked previously in healthcare management consulting, health services research, clinical practice, and healthcare administration…

For clinical applications of AI, it’s still early; most are unlikely to be found at the patient’s bedside and are still in the research…

The rare diseases Duchenne and Becker are X-linked recessive neuromuscular disorders.1 They are characterised by progressive…

Climate change is happening, with the evidence clearly demonstrating an increase in global temperatures; extreme weather events…

Nebulisers are devices used to rapidly deliver high doses of medication to the lungs in people with respiratory disease…

One in 10 people may be affected by a rare disease (RD) in their lifetime.1 This is the surprising paradox of RDs. While each disease…

Children diagnosed with congenital heart disease (CHD) have an increased risk of developing neurodevelopmental disabilities…

Zinc salts are one of three approved treatments for the autosomal recessive condition Wilson’s disease (WD). Their use was first described…

A previously healthy 17-year-old male was transferred from a community hospital to the authors’ tertiary paediatric emergency department…

Dermatitis artefacta (DA), also known as artefactual skin disease, is a rare psychocutaneous disorder characterised by…

Nipah virus disease is a zoonotic infection caused by the Nipah virus (NiV) of the Genus Henipavirus of the Paramyxoviridae family…

Erection is a neurovascular response accompanied by the release of neurotransmitters. The penis is innervated by autonomic (sympathetic…

Infection leads to an increased rate and duration of hospitalisation, increased treatment costs, and high morbidity and mortality in…

Severe cutaneous adverse drug reactions (SCAR) are a group of rare but potentially life-threatening conditions that can occur in response…

Superior vena cava syndrome (SVCS) is a group of clinical manifestations, caused by an obstruction of venous blood flow to the heart…

Dr Enrique Casado and Professor Lothar Seefried talk about the of early identification of individuals at risk of osteoporosis fractures…

Maternal and fetal outcomes associated with the authors’ approach of Caesarean hysterectomy for placenta accreta spectrum disorders…

I always knew that I wanted to work with children. My mother is a paediatric nurse practitioner, and my father is a child psychiatrist…

In patients with immunoglobulin A nephropathy, use of the endothelin 1 Type A/Ang II subtype 1 receptor antagonist sparsentan can decrease proteinuria and preserve kidney function

Targetted prophylaxis is recommended for people with HAE, but many remain on attenuated androgens. EMJ spoke to two HAE experts who explain how they help patients to make the switch.

Emer Kelly. Respiratory Consultant and General Physician, St. Vincent’s University Hospital, Dublin, Ireland. I had asthma as a child, so…

Kiley Whalen. Physician Assistant, Adirondack Rehabilitation Medicine; Master of Science in Physician Assistant Studies at the Center for…

Methotrexate (MTX), an antimetabolite, has a multifarious mechanism of action that most notably includes folate antagonism, effects on…

Cervical cancer is established as a major cause of morbidity and mortality among females globally.1 In Kenya, and other countries with…

End-stage liver disease (ESLD) represents a non-reversible, advanced stage of cirrhosis, where the hepatic architecture is distorted and…

Endoscopic retrograde cholangiopancreatography (ERCP) includes specialised techniques, such as sphincterotomy, balloon dilation…

Smeeta Sinha National Clinical Director for Renal Medicine, NHS England, UK; Consultant Nephrologist, Northern Care Alliance NHS Foundation…

After being diagnosed with cancer, patients embark on a journey that involves ongoing treatments, and regular visits to healthcare…

Patients with chronic kidney disease (CKD), especially those on chronic haemodialysis (HD), have a higher incidence of nosocomial…

Multiple myeloma (MM) is a disease characterised by the clonal expansion of malignant plasma cells in the marrow, leading to anaemia…

Sickle cell disease (SCD) is a genetic condition caused by mutations in the haemoglobin (Hb) gene, resulting in various complications. One…

HIV is an epidemic in Kenya. Females living with HIV (FLHIV) have an eight-fold increased risk of a pregnancy-related death compared to…

I am interested in family medicine and primary healthcare because primary healthcare is the first gatekeeper in the community…

Mycobacterium tuberculosis causing glomerulonephritis (GN) is a rare occurrence, and its association has been seldom reported…

IgAN, which can lead to CKD and kidney failure, is the most common form of primary glomerulonephritis, predominantly…

Many patients experience impairment following a stroke, including motor or cognitive impairment, urinary incontinence, dysphagia…

First described by German physician Peter Emil Becker in the 1950s, Becker is an X-linked genetic recessive disorder. Like Duchenne…

Methotrexate is a common first-line treatment for rheumatoid arthritis, yet its widespread and habitual usage often leads physicians…

While awareness of the issues facing women leading up to, during, and following the menopause has increased in recent years…

Renal cell carcinoma (RCC) is the most common primary tumour originating from the kidney, and accounts for more than 90% of all renal…

Obesity is a major risk factor for the development of Type 2 diabetes (T2D), with the prevalence of both increasing in a parallel manner…

The optimal dressing is still unclear, despite hypospadias being one of the most prevalent surgical operations. Children’s dressing for…

A spontaneous subcapsular hepatic haematoma (SHH) is both a rare and potentially life-threatening condition. Although the pathogenesis of…

One of the many extra-hepatic manifestations of hepatitis B virus (HBV) infections is vasculitis. While the classic HBV-associated…

Obesity, defined as a BMI greater than or equal to 30 kg/m2, is a condition with rising incidence around the world that contributes…

When I started out way back in the 1980s, addiction was predominantly dealt with by psychiatrists in hospitals, psychiatrists…

Leprosy, also known as Hansen’s disease, is a chronic granulomatous infection. It is non-fatal and slowly progressive. Its causative…

This continuing medical education-accredited symposium, held at the 2023 International Society for Thrombosis and Haemostasis (ISTH)…

The deficiency of arylsulfatase A due to the mutations in the ARSA gene is the cause of a rare inherited lysosomal storage disease…

With a pre-specified aim of improving the standard of care of those living with intermittent catheter use, a roundtable discussion led by…

The climate crisis is a health crisis that has the potential to cause significant morbidity and mortality to human populations…

It is essential to address psychological health, particularly post-traumatic stress disorder (PTSD), among patients who have recovered from…

The first thing is probably the holistic approach to care. Primary care provides care for people for a large part of their life…