Gastroenterology

A long-term observational study found that most patients with IBD-U retained their diagnosis, while experiencing distinct treatment patterns and increased healthcare utilisation.

Large UK study shows HLA-DRB1*01:03 is associated with severe IBD outcomes, including surgery, earlier treatment escalation and higher risk of therapy failure across Crohn’s disease and ulcerative colitis.

Severe gastrointestinal manifestations in paediatric IgA vasculitis are associated with renal involvement, highlighting the importance of early renal monitoring in high-risk children.

Analysis of Crohn’s disease Instagram Reels shows moderate quality and no clear accuracy advantage for medical professionals, with engagement unrelated to content reliability.

A case-control study found significantly higher duodenal eosinophil counts in patients with functional dyspepsia, reinforcing evidence for immune involvement in disease pathogenesis.

A study of 326 patients with IBD found that health anxiety partially mediated the relationship between illness perception and self-management behaviour.

Shared TCR signatures in IBD reveal HLA-DRB1 linked immune patterns across ulcerative colitis and Crohn’s disease, suggesting common antigen driven mechanisms.

A pooled analysis of 11 studies found that female sex, older age, diabetes mellitus, anaemia, and comorbidity burden were associated with osteoporosis after gastrectomy for gastric cancer.