Gastroenterology

Grape seed extract reduced hs-CRP in patients with ulcerative colitis, but most outcomes showed no benefit over placebo.

A pilot study found faecal microbiota transplantation was associated with mucosal E. coli decolonisation and increased mucosal microbial diversity in Crohn’s disease.

Five-year PROFILE follow-up linked early top-down therapy in Crohn’s disease with fewer surgeries, hospital admissions and stricturing or penetrating disease than step-up treatment.

A new super-resolution microscope could help scientists better understand IBD and identify potential targets for treatment.

Bulgarian children with Type 1 diabetes had higher H. pylori and CagA seropositivity than controls, prompting calls for further research.

A narrative review found that GLP-1 receptor agonists supported weight loss in patients with IBD and obesity, while longer-term clinical and endoscopic outcomes remained uncertain.

A Danish nationwide cohort found that anaemia affected 52% of patients with paediatric-onset inflammatory bowel disease at diagnosis and remained associated with disease activity over five years.

Higher UPF intake was associated with increased odds of clinical relapse in Crohn’s disease, although the evidence was rated as very low certainty.