Gastroenterology

A prospective study suggests the serum REG3α biomarker is associated with clinical and endoscopic activity in ulcerative colitis and may complement C reactive protein testing.

Researchers found that PSC-ulcerative colitis has distinct colonic mucosa topography compared with ulcerative colitis but shares a common mast cell state during active disease.

An ongoing Salmonella Stanley outbreak has been linked to flavoured noodle products, with 106 confirmed cases reported across Europe and investigations continuing into the source of contamination.

Patients identify key priorities for brain–gut behavioural therapy, with a new US study highlighting the need for patient-reported outcome measures that better reflect lived experience, symptom management, and behavioural health goals.

A Spanish study found that genetic variants in eosinophilic oesophagitis were associated with disease phenotype, eosinophil counts, and accompanying atopic conditions, including asthma, conjunctivitis, and dermatitis.

A UK Biobank study has validated an oesophageal and gastric cancer risk score using self-reported clinical and lifestyle data to identify adults aged over 50 at elevated risk of upper gastrointestinal cancer.

Specific foods may be associated with a painful gastric glitch, a proposed phenotype of postprandial epigastric pain syndrome characterised by food-triggered symptoms, increased duodenal mast cells and altered gastric wall motion.

Fluid resuscitation in acute pancreatitis shows that crystalloid type and infusion rate interact to influence hospital length of stay in mild disease.