Gastroenterology

Dietary treatments may be more effective than pharmacological options for managing irritable bowel syndrome (IBS) symptoms.

The pioneering COLO-DETECT trial has demonstrated the potential of AI to significantly enhance the detection of colorectal polyps during colonoscopies.

A comprehensive meta-analysis has identified key risk factors associated with inadequate bowel preparation before colonoscopy.

Upadacitinib may offer superior disease management than tofacitinib for patients with ulcerative colitis.

Patients with painful chronic pancreatitis and a dilated pancreatic duct benefit more from early surgery than an endoscopy-first approach.

A new cohort study highlights significant racial and ethnic disparities in mortality rates associated with early-onset colorectal cancer.

While a gluten-free diet improves wellbeing, it does not fully reverse coeliac disease impact on gut function or microbiota composition, according to new research.

The 10-year study challenges previous assumptions about gastric cancer risks in Western populations, particularly among Caucasian Americans.

CVS can be highly disabling, but prompt recognition and effective management can dramatically improve patients’ quality of life.

Recent research has revealed significant regional disparities in the performance of computer-aided diagnosis (CADx) systems during colonoscopy.

Higher use of televisit services, via video or phone, was linked to a reduced likelihood of hospitalisation.

A new multisociety clinical guide provides a framework for GLP-1RA usage to ensure safe patient management.

Beer-only consumers may face greater health risks due to poorer dietary habits and unhealthy lifestyle factors.

The American Gastroenterological Association has released a new set of guidelines to assist healthcare providers in the pharmacological management of moderate-to-severe ulcerative colitis.

Individuals without a family history of colorectal cancer could safely extend their colonoscopy screenings from the standard 10-year interval to 15 years.

A systematic review investigating the impact of glucagon-like peptide-1 receptor agonists on alcohol consumption has yielded some promising results.

A large-scale analysis has revealed a significant link between coffee consumption and the gut microbiome, driven primarily by the presence of Lawsonibacter asaccharolyticus.

Gastroparesis diagnoses based solely on gastric emptying studies may overlook broader gastrointestinal dysmotility, necessitating a shift in diagnostic approaches.

New research highlights the utility of the PRECISE-DAPT score in predicting GI bleeding risk in patients undergoing dual antiplatelet therapy after percutaneous coronary intervention.

Findings indicated that patients taking ARBs had a higher likelihood of experiencing persistent symptoms and markers of poor small bowel healing.

Certain obesity types significantly increase risk of death in individuals with digestive diseases, according to a recent study analysing obesity’s impact on mortality.

A retrospective study analysed over 15 years of follow-up data from patients who underwent Roux-en-Y gastric bypass.

This study investigated how vedolizumab affects the immune cells circulating in the blood, particularly focusing on which patients responded well to the therapy.

A new molecular classification for gastrointestinal stromal tumours has uncovered four distinct subtypes and identified a potential tumour suppressor gene.

A recent study highlights a concerning link between the use of GLP-1 receptor agonists (GLP-1RA) and inadequate bowel preparation for colonoscopies.

A recent study from Stanford Medicine highlights both promise and caution surrounding newly approved blood tests for colorectal cancer screening.

Primary sclerosing cholangitis raises colorectal cancer risk even in patients without inflammatory bowel disease, according to new findings presented at ACG 2024.

Research presented at the ACG 2024 has demonstrated high accuracy of small intestinal contrast ultrasonography (SICUS) for assessing small bowel Crohn’s disease

AI-DRIVEN endoscopic ultrasound has demonstrated high accuracy in detecting and differentiating pleomorphic pancreatic lesions, according to new research presented at the American College of Gastroenterology 2024 Annual Meeting.

Research presented at the American College of Gastroenterology (ACG) 2024 Annual Meeting showed that rifaximin monotherapy significantly reduces the risk of recurring overt hepatic encephalopathy

New research presented at the American College of Gastroenterology (ACG) Annual Meeting suggests that GLP-1 receptor agonists (GLP-1RAs) may significantly lower the risk of pancreatic cancer in patients with type 2 diabetes

The American College of Gastroenterology (ACG) has issued a new clinical guideline to help healthcare providers more effectively manage Helicobacter pylori….

A Danish genome-wide association study has identified a genetic marker linked to severe ulcerative colitis, a chronic inflammatory bowel disease with increasing incidence. 

A trial investigated the effects of adding Helicobacter pylori stool antigen testing to colon cancer screening on rates of gastric cancer incidence and mortality. 

Pioneering research presented at UEG Week 2024 has revealed a new treatment approach for Type 2 diabetes that could reduce the need for insulin therapy.  

A study presented at UEGW 2024 is exploring a breakthrough imaging technique aimed at improving treatment outcomes for patients with locally advanced oesophageal cancer.

At UEG Week 2024, researchers showed that TP53 mutations and chromosomal changes improve prediction of oesophageal adenocarcinoma in low-risk Barrett’s oesophagus.

A groundbreaking study presented at UEG Week 2024 has revealed distinct antibody responses in Crohn’s disease and ulcerative colitis apparent years before diagnosis.

Leading health experts at UEG Week 2024 are calling for the implementation of a national, quality-assured colorectal cancer screening programme for individuals aged 45–75.

A new guideline from The American Society of Colon and Rectal Surgeons highlights a personalised, multidisciplinary approach to managing chronic constipation

New research has highlighted a concerning rise in early-onset colorectal cancer cases, accompanied by more aggressive disease and inferior survival.  

A multicentre study shows endoscopic submucosal dissection is a safe, effective treatment for high-risk colorectal neoplasia in patients with inflammatory bowel disease.

Individuals with upper gastrointestinal mucosal damage may be at an increased risk of developing Parkinson’s disease later in life.

New research from DDW 2024 shows older adults with inflammatory bowel disease treated with advanced therapies may face a slightly increased risk of infection.

Metabolic bariatric surgery offers substantial protective benefits for patients with chronic kidney disease, Type 2 diabetes, and obesity, according to new research.

Recent research highlights a significant increase in the risk of Barrett’s esophagus following sleeve gastrectomy, a commonly performed bariatric surgery

A study highlights the potential of intestinal ultrasound as a valuable tool for predicting treatment outcomes in children with moderate-to-severe ulcerative colitis.

Aspirin may help reduce the risk of colorectal cancer among individuals with unhealthy lifestyles, according to recent research.

A study on antimicrobial therapies for patients with acute cholangitis has suggested that a shorter duration of antimicrobial therapy might be sufficient for successful outcomes.

New data has revealed that screening for colorectal cancer using faecal immunochemical tests is significantly associated with a reduction in mortality rates.

Researchers have identified that hypoalbuminemia within the first 24 hours of hospital admission for acute pancreatitis could serve as a significant predictor of adverse outcomes.

Research explores the prevalence of post-infection irritable bowel syndrome and functional dyspepsia after acute gastroenteritis.

Changes in body composition and metabolic markers could enable the early detection of pancreatic ductal adenocarcinoma.

New research has shed light on the potential of the gut microbiota in predicting recurrence of Crohn’s disease following surgical remission.

Use of glucagon-like peptide 1 receptor agonists is associated with an increased risk of aspiration pneumonia in patients undergoing gastrointestinal endoscopy, according to recent research.

Novel research has shed light on the efficacy of proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients undergoing invasive ventilation.

Hematochezia and abdominal pain are the initial symptoms in nearly half of individuals with early-onset colorectal cancer, according to recent research.

Recent research has highlighted the significant impact of a catered low-fat, high-fibre (LF/HF) diet on patients with Crohn’s disease.

AI-assisted navigation can enhance the coordination and delivery of specialty cancer services for patients with suspected pancreatic cancer, according to new research.

A new study has investigated the link between oral antibiotic use in adults and increased risk for early-onset colorectal cancer.

A new study has found that post-polypectomy surveillance colonoscopy is associated with a significantly lower risk of incident colorectal cancer.

Lockdown and social distancing measures implemented during the COVID-19 pandemic are associated with increased BMI and prevalence of non-alcoholic fatty liver disease (NAFLD)…

Eosinophilic oesophagitis, an increasingly common paediatric condition, presents significant treatment challenges due to low remission rates and high recurrence.

Supportive care is the main approach when it comes to treating acute pancreatitis. Retrospective studies of the causes and characteristics of hospitalised patients can help pinpoint and eliminate potential triggers…

Infliximab (IFX) is increasingly the prescribed therapy for chronic inflammatory bowel disease in paediatric patients. Successful treatment with IFX is dependent on numerous factors…

A study reveals improvements for children with coeliac disease, highlighting the potential advantages of early detection through large-scale screening.

A study analysed adherence to proton pump inhibitors in patients with Barrett’s oesophagus, identifying five patterns influencing treatment consistency.

Researchers have set out to explore the link between obesity and faecal incontinence, as the relationship is uncertain.

A recent study’s findings indicate that extending the colonoscopy screening interval could be safe.

A study from University of Gothenburg, Sweden, states that dietary management surpasses medications for irritable bowel syndrome, with about 70% experiencing significant symptom improvement,

GLP1-RA drugs for diabetes may heighten risk of gastric retention during upper endoscopy. Research suggests continued use may not warrant procedure cancellations.

This News Feature explores the current use of anti-TNF combination therapy with immunomodulators for Crohn’s disease and ulcerative colitis in adults and children.

Patients who underwent surgery for inflammatory bowel disease (IBD) reported better physical health 1 month after surgery, according to research. Read more.

Anti-TNF therapy can lead to significant improvement in growth disturbances among children with Crohn’s disease: the number of patients with growth disturbances notably decreased 12 and 24 months after initiation of anti-TNF therapy.

This News Feature explores the current opinions of leading gastroenterologists on the early use of anti-TNFs for Crohn’s disease and ulcerative colitis.

This News Feature explores the changing landscape of inflammatory bowel disease care focusing on personalised approaches and shared decision-making to support therapy selection.

This news feature considers the role of nutrition in IBD, highlighting the latest insights, and importance of dietary choices along with recent guideline recommendations.

Recent data suggest that older patients presented with personalised information about the benefits and harms of colorectal cancer screening were more likely to receive screening orders that aligned with benefit.

A research team conducted a retrospective, multicentre, matched case-control study to investigate the association between preterm birth and infantile appendicitis. Results suggests preterm infants face an increased risk of developing appendicitis during their first year of life.

At this year’s American College of Rheumatology (ACR) 2023 Convergence, held in San Diego, California, USA, between 10th–15th…

A new study suggested that patients with inflammatory bowel disease could have an increased risk of contracting respiratory syncytial virus and may be eligible to receive RSV vaccines.

A systematic review and meta-analysis have indicated 10 interventions that could improve adenoma detection rate (ADR) during screening-related colonoscopies. Read more.

This News Feature explores the impact of anti-TNF biosimilars on global healthcare as a cost-effective solution, enhancing access to treatment options for inflammatory conditions.

This News Feature explores the approaches for optimising anti-TNF therapies in gastroenterology, based on content delivered during UEG…

Despite anti-reflux surgery being recommended for patients with Barrett’s oesophagus in order to decrease the risk of later developing oesophageal adenocarcinoma, recent research suggests that it may be no more effective than anti-reflux medication.

Recent research has shown that alcohol use during the early stages of direct-acting antiviral treatment was not linked to reduced odds for achieving sustained virologic response (SVR) in patients with chronic HCV infection.

This News Feature explores the role of psychological stress in exacerbating inflammatory bowel disease, and offers insights into mind–body care to empower patients.

This News Feature discusses the role of anti-TNF therapies in treating inflammatory bowel disease (IBD), highlighting their impact…

Obstructive sleep apnoea is often accompanied by nocturnal gastro-oesophageal reflux. Recent studies show consistent use of positive airway pressure may decrease the odds for nGOR. Read more.

Studies have shown that dysphasia, gastroparesis, and irritable bowel syndrome without diarrhoea may come with an increased risk of later developing the Parkinson’s disease. Read more.

Colorectal cancer incidence among adults under 50 is rising globally. However, the factors underlying the worse outcomes are unclear…

Survivors of colorectal cancer often experience long-term symptoms following treatment. However, GI symptoms are relatively under-investigated…

Bariatric surgery lowers the risk for major adverse cardiovascular events and mortality in patients with obesity and obstructive sleep apnoea…

This study aims to evaluate the quality of gallbladder cancer surgery programmes at different centres through established benchmark values…

Inflammation induced by gut microbial dysbiosis may play a role in the development of gestational diabetes in the first trimester of pregnancy…

Prophylactic use of amoxicillin-clavulanate with prednisolone does not improve survival in patients with severe alcohol-related hepatitis…

Blood ceramide levels could help predict whether patients with Type 2 diabetes who undergo gastric bypass surgery will experience remission…

A study discovered that intestinal inflammation in Crohn’s disease frees up chemicals, which nourish the growth of bacteria, such as E. coli.

Screening for colorectal cancer (CRC) could significantly reduce risk in females if carried out before the age of 50 years…

VALUABLE advances in the diagnosis of aerodigestive conditions have been made with the introduction of a new integrated framework…

Oesophageal atresia (OA) is a birth defect that causes the oesophagus to end in a pouch rather than connecting to the stomach…

Evidence linking frequent consumption of processed meat with higher risk of death in IBD patients has been reported…

A a safe and effective profile for nerve stimulation treatment in children and adults with mild-to-moderate IBD has been discovered…

LACK of diversity in pancreatic cancer clinical trials means that many minority patients remain conspicuously absent from consideration…

Busada’s study focused on testosterone, the primary male sex hormone, but also investigated glucocorticoids, steroid hormones with…

This procedure involves endoscopic creation of an antireflux ‘Omega’ valve, showing promise by acting as a durable barrier to reflux and exhibiting fewer symptoms than that seen in traditional fundoplication.

A study upon Pfizer and Moderna vaccines has revealed fewer complications in patients with inflammatory bowel diseases (IBD) compared with the general population.

PERIANAL Crohn’s disease (PCD) with a severe phenotype has been shown to be associated with poor outcomes despite growing use of immunomodulators and…

HUNDREDS of different species of bacteria live in the gut in a community estimated to contain 40 trillion cells. Previous studies have established…

Irritable bowel syndrome cause many people a lot of pain. A recent research has discovered the biological mechanism for this, so a more efficient treatment.

100 BILLION bacteria, approximately, live in our intestines. Medical researchers have so far struggled to study these bacteria in their natural…

A review of published academic studies has found that almost 20% of COVID-19 patients may only display gastrointestinal symptoms.

LONG-TERM use of proton pump inhibitors (PPI) has been linked to increased risk of Type 2 diabetes mellitus (T2DM), in a large-scale, observational…

ROBOTICS guidance for colonoscopy may not be far away, following progress in the development of a semi-autonomous procedure. After 12 years of…

MICROBIOTA from stool samples of patients with nonalcoholic fatty liver disease (NAFLD) may be used to predict which individuals are at greatest risk…

PROTEIN-PUMP inhibitors (PPI) taken by those with indigestion may increase an individual’s risk of developing COVID-19.

COLORECTAL CANCER predominantly stems from a genetic mutation of APC. In general, a major proportion of people with the mutation…

COVID-19 has spread throughout the word and drastically affected everyday life and clinical practice. Although the disease…

OPIOIDS are commonly used as a means of pain management in inflammatory bowel disease (IBD), but it is well-known that there are serious concerns…

A CAPSULE that can be swallowed could be the answer to accurate diagnoses of small intestinal bowel overgrowth (SIBO), which is estimated to effect…

THE COMPLEX nature of dietary benefits and risks, particularly regarding disease prevention, requires ongoing attention from nutritionists…

NEW FINDINGS have revealed a specialised sub-set of cells residing in the gut as being important regulators of intestinal inflammation through a body…

FAECAL TRANSPLANTS can boost the immune system of aged mice in the gut by stimulating the microbiome. A study by a group of immunologists from the…

COLONIC EXAMINATIONS could see a change with the advent of a miniature robotic capsule which could remove the need for invasive and painful endoscopies…

RESEARCH into early-onset colorectal cancer (CRC) has found unique subgroups among younger patients and has outlined risk factors and prevalence of…

Obesity is a known risk factor for a multitude of cancers, including pancreatic, ovarian, and liver, and contributes to an estimated 15–20% of all cancer…

BOWEL DISEASE in premature babies presents a significant impact on survival rates, with the immaturity of the gastrointestinal tract causing bacterial…

TREATMENT of coeliac disease may now be possible using a compound originally developed for cystic fibrosis. While current remedies for coeliac disease…

EMJ Gastroenterology 7.1 is now available, presenting a full review of UEG Week 2018, this year held in the Austrian capital: Vienna.

A study has shown that prehabilitation, a structured exercise and nutrition conditioning programme prior to operation, leads to an improvement in…

Laparoscopic pancreatoduodenectomy (LPD) has been shown by the results of the PADULAP trial, which was conducted from 2013–2017, to lead to both shorter…

Long-living macrophages in the gastrointestinal system play a crucial role in ensuring that the intestine functions normally in mice, researchers from…

Cancer of the oesophagus could be prevented by treating severe heartburn medically or surgically, according to a study from the Karolinska Institutet…

Rotavirus vaccine should be included in all national immunisation programmes in line with the World Health Organization (WHO) recommendation, a study…

Gut–brain signalling is a topic of paramount importance in modern biology and medicine. It is understood that the bidirectional signalling, mainly via…

Cell communication has been shown to be a contributing factor to intestinal inflammation, according to work carried out by scientists at Michigan State…

Coeliac disease is the most common food-related chronic disease among children in Europe, yet experts now believe that up to 80% of cases are undiagnosed.

Researchers presenting at the 51st ESPGHAN Annual Meeting have today revealed the results of a new study which proves the efficacy and effectiveness of…

Targeted probiotic supplementation in breastfed infants can significantly reduce the potential for antibiotic resistance, new research presented today at…

A life changing silicone adhesive that prevents abdominal stomas from leaking and provides a range of benefits for patients and healthcare professionals…

Calcium supplements have been shown to increase the risk of developing certain types of precancerous growths in the rectum or colon up to 10 years after…

A strong link between inflammatory bowel disease (IBD) and myocardial infarction has been established from a study of >22 million IBD patients. With…

New drugs to treat a particular type of worm called whipworm could be developed following vital insights into the bacteria that live in the parasites’…

Autoimmune responses can be initiated by bacteria residing in the small intestine that are able to translocate to other regions of the body, according to…

Malignant growth and metastasis in colorectal cancer is driven by the manipulation of a signalling protein caused by growth factors, according to…

IMPROVED diagnosis of pancreatic cancer and better determination of the stage of the condition can be achieved through the use of a PET-CT scan…

NEW insights into the strategies bacteria use to compete with one another have been revealed by researchers from the University of Oxford, Oxford…

SPECIFIC immune cells in the large intestine are moved by cholesterol metabolites, a process which underpins the formation of lymphoid tissue in the…

STOMACH CANCER prevention may be possible through treatment of chronic periodontal disease and control of periodontal pathogens, according to results of…

IN VITRO three-dimensional (3D) cell systems are the subject of intense research, with the aim of one day replacing existing animal models. Now, a stem…

The European Medical Journal welcomes you to their annual publication of EMJ Gastroenterology…

A PROTEIN from a worm parasite could provide the basis for future treatment options for inflammatory bowel diseases, according to researchers at the…

MECHANICAL valves have very good long-term mortality benefits and should be used more often, particularly in younger patients who require mitral-valve…

OESOPHAGEAL cancer could be diagnosed up to 8 years before the first symptoms appear, enabling earlier treatment of the condition, according to…

Tel-Aviv, Israel/Raleigh, NC, USA, 03 October, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“Red Hill” or the “Company”)…

PROTEOMIC study of bowel cancer cells identifies common protein mutations and allows the prediction of treatment response….

BACTERIAL communities in the gut of Parkinson’s patients differ to those of healthy people, potentially providing an early indicator of the…

RedHill Biopharma Ltd. announced that it has initiated promotion of Esomeprazole Strontium Delayed-Release (DR) Capsules 49.3 mg1 in the U.S.

It’s a deadly secret that many of us keep inside. It’s a burden that only we can feel, while acting completely unaffected to the outside world.

Tel-Aviv, Israel / Raleigh, NC, USA, 17 July, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the “Company”)…

Tel-Aviv, Israel / Raleigh, NC, USA, 12 July, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the “Company”)…

BACTERIA discovered in the gut could prove invaluable for preventing Listeria infection, according to a new study from researchers at the Memorial Sloan…

SUPPRESSING a specific protein could be an effective way of combatting pancreatic cancer, according to a new study performed by researchers from the Keck…

Tel-Aviv, Israel, Raleigh, USA, 14 June, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the “Company”)…

A new study highlights that children suffering from IBD are not meeting the daily recommended intake of calcium and vitamin D.

Prague, 13 May, 2017 – The results from a Norwegian study show that a new genetic test for characterising intestinal microbiota may help to diagnose…

United Kingdom, May 09, 2017: Welcome to the newest edition of our EMJ Urology eJournal, packed with the latest urological developments. This issue is…

Osimertinib improves cancer-related symptoms in patients with advanced lung cancer, according to an analysis presented at the ELCC.

Beerse, Belgium, 28 April, 2017 – Janssen-Cilag International NV (“Janssen”) today announced that the European Commission (EC) has granted approval to…

Tel-Aviv, Israel, April 18, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the “Company”), a specialty…

Melbourne, Australia, April 03, 2017 – Retinal implant innovator Bionic Vision Technologies (BVT) today announced it had raised US $18 million…

CLINICAL relapse risk amongst individuals with ulcerative colitis (UC) more common if the levels of vitamin D in the blood are lower than required…

A POTENTIAL link has been discerned between gut bacteria and behaviour in patients with irritable bowel syndrome (IBS), a common gastrointestinal…

Tel-Aviv, Israel, March 21, 2017 – RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the “Company”), a specialty…

United Kingdom, March 2, 2017: A warm welcome to the year’s first issue of the flagship eJournal, the European Medical Journal. Contained within is a…

SCIENTISTS have developed a non-invasive bisulphite sequencing test to detect bladder cancer using urine samples that matches the performance of a…