Gastroenterology

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Gastric Cancer Risk Score Validated in UK Biobank

July 2026

A UK Biobank study has validated an oesophageal and gastric cancer risk score using self-reported clinical and lifestyle data to identify adults aged over 50 at elevated risk of upper gastrointestinal cancer.

Health Anxiety Mediates Self-Management in IBD

Health Anxiety Mediates Self-Management in IBD

A study of 326 patients with IBD found that health anxiety partially mediated the relationship between illness perception and self-management behaviour.

IBD

Shared T Cell Signatures Identified In IBD

Shared TCR signatures in IBD reveal HLA-DRB1 linked immune patterns across ulcerative colitis and Crohn’s disease, suggesting common antigen driven mechanisms.

Osteoporosis Risk Factors Identified After Gastrectomy

A pooled analysis of 11 studies found that female sex, older age, diabetes mellitus, anaemia, and comorbidity burden were associated with osteoporosis after gastrectomy for gastric cancer.

Colorectal cancer

AI Can Be Used to Predict Colorectal Cancer Prognosis

Researchers constructed and validated explainable machine learning models using routine blood indices to determine overall survival outcomes in patients with colorectal cancer.

rectal cancer

Machine Learning Optimises Ileostomy Use in Rectal Cancer

Machine learning RTID system reduces unnecessary temporary diverting ileostomy use in rectal cancer surgery while maintaining similar anastomotic leakage rates.

Microbiome Maturation Influences Neurodevelopmental Disorder Risk

Researchers investigate how specific gut bacteria might modify the impact of perinatal epigenetic changes associated with neurodevelopmental disorders.

Irritable bowel syndrome

Herbal Preparation Reveals Benefits for Irritable Bowel Syndrome

Herbal preparation of myrrh, chamomile extract and coffee charcoal shown to provide benefits for those with irritable bowel syndrome.

Spicy Food and Alcohol Intake Shown to Shape Gut Microbiome

A new Korean metagenomic study found that ingesting spicy food and alcohol in conjunction can negatively affect the gut microbiome and potentially cause dysbiosis.

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