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Cannabis Use Rarely Precedes Hard Drug Use, Study Finds

July 2025

In a large national survey of cannabis users in Japan, researchers found little evidence to support the long-standing “gateway drug” hypothesis, a theory suggesting that cannabis use leads to subsequent consumption of more harmful substances such as methamphetamine or other illicit drugs.

Cannabis Use Rarely Precedes Hard Drug Use, Study Finds

In a large national survey of cannabis users in Japan, researchers found little evidence to support the long-standing “gateway drug” hypothesis, a theory suggesting that cannabis use leads to subsequent consumption of more harmful substances such as methamphetamine or other illicit drugs.

New Guidelines Aim to Transform Duchenne Orthopedic Care

A newly developed UK consensus guideline outlines critical recommendations for the orthopedic management of children and young people with Duchenne muscular dystrophy (DMD), addressing an urgent need for standardized fracture and surgical care.

New Biomarkers Strengthen McDonald Criteria for MS Diagnosis

Two promising biomarkers, the kappa free light chains (kFLC) index and central vein sign (CVS), have been incorporated into the revised 2024 McDonald criteria, offering improved diagnostic precision for multiple sclerosis (MS) and radiologically isolated syndrome (RIS).

Warning Signs of Sudden Death in Epilepsy

EEG suppression after seizures may signal increased SUDEP risk in children with epilepsy, according to a new study evaluating clinical and electrophysiological indicators.

New Insights into VMAT2 Use for Child Movement Disorders

VMAT2 inhibitors may offer effective symptom relief for pediatric hyperkinetic movement disorders, according to a new retrospective study reviewing over a decade of clinical use.

Breast Cancer Survivors Show Unexpected Lower Alzheimer’s Risk

Breast cancer survivors may face a lower risk of Alzheimer’s disease than their cancer-free peers, according to a large retrospective cohort study examining long-term cognitive outcomes following treatment.

New Migraine Treatment Blends Telehealth Approaches

An emerging treatment model for migraine integrates behavioral and pharmacologic approaches via telehealth, potentially improving access and outcomes for patients with this highly disabling neurological condition.

Mood Symptoms Linked to Poorer Progressive Supranuclear Palsy Outcomes

Depression and anxiety, not motor decline, are the strongest predictors of quality of life in patients with progressive supranuclear palsy (PSP), according to a new study that underscores the pressing need for comprehensive symptom management beyond traditional motor assessments.

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