Oncology

A randomized controlled trial has found that Bojungikgi-tang (BJT), a traditional East Asian herbal medicine, significantly improved symptoms of anorexia and atopic dermatitis (AD) while altering the gut microbiome in affected patients.

Switching to camizestrant upon detection of an ESR1 mutation, before clinical disease progression, may extend progression-free survival (PFS) for patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancer, according to results from the Phase III SERENA-6 trial.

As cancer therapies evolve and autoimmune diseases become more prevalent, the intersection of oncology and rheumatology, onco-rheumatology, is emerging as a critical field demanding transdisciplinary care.

Efforts to optimize treatment for Stage II testicular seminoma are intensifying, as new approaches aim to reduce long-term toxicity while preserving the high cure rates associated with standard therapies.

In a large retrospective study, percutaneous balloon dilation was found to have a statistically significant advantage over open reconstructive surgery for treating high-grade benign biliary strictures, especially those classified as Bismuth-Strasberg type E4 and E5, which are known for technical complexity and recurrence risk.

A gene-based assay may help guide adjuvant chemotherapy decisions in early-stage non-squamous non-small cell lung cancer (NSCLC), according to interim results from a randomized clinical trial presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.

Results from an international Phase III clinical trial presented at the 2025 ASCO Annual Meeting evaluate a treatment regimen combining encorafenib and cetuximab with mFOLFOX6 chemotherapy in patients with previously untreated BRAF V600E-mutant metastatic colorectal cancer (mCRC).

A new study exploring women’s body image after mastectomy sheds light on the complex emotional and psychosocial challenges these patients face during and after breast cancer treatment.