Oncology

Investigational trastuzumab rezetecan provides robust survival benefits for patients with HER2-positive metastatic breast cancer.

Novel combination therapy shows promising clinical antitumor activity in patients with heavily pretreated recurrent ovarian cancer.

Oncolytic immunotherapy with nivolumab yields durable responses in patients with anti-PD-1 failed advanced cutaneous melanoma cases.

Elevated BMI did not significantly worsen most short term outcomes after robot-assisted radical prostatectomy for prostate cancer.

Annual multi-cancer early detection screening reduces stage IV diagnoses and emergency presentations in randomized clinical trials.

Dietary arginine availability directly drives MHC class I translation to enhance host immunity against cancer and viral infection.

Germline genetic background strictly shapes cancer evolution trajectory and driver mutation selection in experimental liver cancer.

Neonatal dried blood spots reveal potential associations between early chemical exposure and childhood acute lymphoblastic leukemia.