Oncology

An NHS programme demonstrated the feasibility of clinician-light breast cancer genetic testing, identifying germline pathogenic variants in 4.7% of patients.

A nationwide study found that pancreatic cancer mortality remained associated with socioeconomic deprivation in Japan, particularly among men aged under 75 years.

A rapid genomic test could identify brain tumour types within hours, helping doctors plan surgery and treatment sooner.

Blood DNA methylation patterns may identify increased prostate cancer risk up to eight years before diagnosis.

Long-term wildfire smoke exposure was associated with poorer survival amongst older patients with lung cancer.

Glioma-derived GAA stimulates surrounding neurons and promotes tumour growth, revealing a potential treatment target.

A qualitative study developed an implementation-aware Target Product Profile for mobile cancer testing, identifying 42 attributes and key handover requirements.

Targeted mRNA nanoparticles reprogrammed tumour-associated macrophages to support antitumour T-cell activity.