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Neratinib Targets Vascular Inflammation in Atherosclerosis Models
January 2026
Neratinib markedly reduced vascular inflammation and atherosclerosis in mice by targeting ASK1, boosting effects with rosuvastatin.
Read more
4 May 2025
Phase III Pembrolizumab Trial in Head and Neck Cancer: AACR 2025
Patients with newly diagnosed, locally advanced head and neck squamous cell carcinoma (HNSCC) may soon benefit from a major shift in treatment strategy, as phase III trial data show that perioperative pembrolizumab significantly improves outcomes when added to standard care.
2 May 2025
FDA Fast Track Therapy Targets
HER2
-Mutated NSCLC: AACR 2025
Promising new data emerged on zongertinib, an investigational oral therapy targeting HER2 mutations in advanced non-small cell lung cancer (NSCLC), was presented at the AACR Annual Meeting 2025 in Chicago.
2 May 2025
Liquid Biopsy Detects Colorectal Cancer Recurrence Months Early: AACR 2025
At the American Association for Cancer Research (AACR) Annual Meeting 2025 in Chicago, new data revealed that a liquid biopsy using circulating tumor DNA (ctDNA) could detect colorectal cancer recurrence significantly earlier than imaging, with ctDNA signals appearing up to 416 days before clinical detection.
2 May 2025
Off-the-Shelf Cell Therapy Induces Remission in Relapsed AML: AACR 2025
At the AACR Annual Meeting 2025 in Chicago, researchers unveiled promising early results from a novel cell therapy that could reshape treatment options for patients with relapsed or refractory acute myeloid leukemia (AML).
1 May 2025
Immunotherapy Removes Surgery Need in dMMR Cancers: AACR 2025
Neoadjuvant immunotherapy using PD-1 blockade has demonstrated the potential to eliminate the need for surgery in patients with early-stage mismatch repair-deficient (dMMR) cancers, according to groundbreaking data presented at the AACR Annual Meeting 2025.
1 May 2025
Oral Therapy in KRAS G12D-mutated Lung Cancer: AACR 2025
At the AACR 2025 Annual Meeting in Chicago, new data presented on the investigational agent zoldonrasib showed encouraging clinical activity in patients with non-small cell lung cancer (NSCLC) harboring the KRAS G12D mutation.
1 May 2025
Lung Nodule Diagnosis Delays Tied to Demographics
Timely lung cancer diagnosis and treatment are essential for improved survival, but new research shows that patients with suspicious lung nodules continue to experience critical delays at multiple stages of care.
29 Apr 2025
Risks of Nonroutine Discharge After Spinal Metastasis Surgery
Patients undergoing spinal surgery for metastatic disease face a heightened risk of nonroutine discharge, often leading to increased healthcare costs and higher readmission rates.
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