Oncology

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Clinician reviewing longitudinal patient-reported outcomes and EQ-5D quality-of-life data in an older adult cancer cohort

Making Longitudinal Patient-Reported Outcomes Clinically Interpretable

February 2026

New guidance details valuable approaches to analyze longitudinal patient-reported outcomes when many patients die during follow-up.

Accelerated brain aging concept in adult childhood cancer survivors, highlighting neurocognition testing and vascular risk biomarkers

Accelerated Brain Aging Tied to Neurocognition

Adult childhood cancer survivors demonstrated accelerated brain aging that tracked with cranial radiation and poorer neurocognition.

Cardiovascular disease mortality risk after cancer diagnosis concept image showing heart and oncology care theme

Cardiovascular Disease Mortality Higher After Cancer Diagnosis

Cancer diagnosis was linked to cardiovascular disease mortality in UK Biobank, implicating inflammation and coagulation proteins.

Robotic assisted versus laparoscopic surgery concept for obese colorectal cancer patients

Robotic Assisted Versus Laparoscopic Surgery in Obese Colorectal Cancer

Robotic surgery shortened hospital stay versus laparoscopy for obese patients with colorectal cancer, with comparable safety overall.

Surgeon and radiation team planning IOERT for locally recurrent rectal cancer after chemo-reirradiation

Locally Recurrent Rectal Cancer After Chemo Reirradiation

Neoadjuvant chemo-reirradiation alongside IOERT surgery produced manageable toxicity, and 75.7% two-year survival in patients with LRRC.

Host-related determinants of immunotherapy response in NSCLC linked to body composition, metabolism, sex, and systemic inflammation

Obesity, Sarcopenia, Host-Related Determinants of Immunotherapy Response in NSCLC

Host-related determinants of immunotherapy response in NSCLC hinge on body composition, metabolism, sex, and systemic inflammation.

Dual Enrollment Strategy Supports Trial Diversity

An analysis confirms dual enrollment at private and safety-net hospitals is feasible for Phase I solid tumor trials, yielding higher diversity and similar patient survival rates.

Researchers reviewing oncology study protocol for cancer clinical trials development in Latin America

Cancer Clinical Trials Development in Latin America Lags

Cancer clinical trials development in Latin America underperforms globally yet strengths could expand equitable evidence worldwide.

Lung cancer blood test using FT-IR microspectroscopy to identify a circulating tumour cell in a cytospun blood sample.

New Blood Test Detects Single Lung Cancer Cell

FT-IR microspectroscopy blood test detected a single circulating tumor cell in one patient with lung cancer, cytospun raw blood sample.

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