Rheumatology

A systematic meta-analysis reported 88.0% returning to sport after unicompartmental knee arthroplasty, regardless of implant design.

Qualitative interviews found trust and clear roles shape vaccination decisions in inflammatory rheumatologic disease care settings.

In juvenile arthritis, parent and physician global assessment discordance tracked with higher pain and catastrophizing scores.

Frailty predicts falls in adults with type 2 diabetes Hanoi geriatric hospital documentation demonstrates quadrupled-odds annually.

Baseline serum CXCL6 levels distinguished patients with ANCA-ILD and independently predicted ILD progression during follow up later.

Serum levels of DKK1 may help clinicians estimate disease activity in patients with antineutrophil cytoplasmic antibody associated vasculitis.

People with hidradenitis suppurativa should be screened in rheumatology for subclinical spondyloarthritis, according to a real-world study.

Periprosthetic bone density after unicompartmental knee arthroplasty may follow a predictable early loss then recovery pattern.

Accelerated biological aging may be a missing link between hyperuricemia, rising serum uric acid, gout, and diet-driven prevention.

Biomimetic drug delivery systems are reshaping rheumatoid arthritis management by targeting inflamed joints more precisely today.

Muscle flexibility training may offer a targeted non-pharmacologic option to ease chronic pain in older adults.

The new systemic juvenile idiopathic arthritis recommendations outline evidence-based treatment strategies that prioritize early pathway inhibition and careful glucocorticoid use.

Young adult rheumatology transitional care benefits when patient priorities directly guide targeted service improvements and design.

Large-scale robust analyses link lupus genetic predisposition to distinct clinical manifestations across biobank and patient cohorts.

IL-26 is emerging as a relevant inflammatory signal in multiple autoimmune diseases, shaping disease-specific immune responses.

Transverse tibial transport improved limb salvage outcomes in recalcitrant diabetic foot ulcers among six patients in an international case series.

AI can simplify complex rheumatology literature, making it easier for patients to understand essential health information.

Racial disparities continue to affect kidney transplant outcomes in patients with SLE, even after the 2014 revision of the Kidney Allocation System designed to improve organ distribution equity.

Methotrexate use does not appear to increase the risk or accelerate the progression of interstitial lung disease in patients with rheumatoid arthritis.

At ACR 2025, early data of CTA313, a universal CD19/BCMA CAR-T therapy, demonstrate safety and strong responses in refractory lupus, offering hope for durable remission.

New research presented at ACR 2025 shows GLP-1 receptor agonists, used for diabetes and obesity, may reduce rheumatoid arthritis flares and inflammation.

New research presented at ACR 2025 reveals IL-6 and CCL3 as predictive markers of fetal heart block in anti-Ro–positive pregnancies, paving the way for early detection and prevention.

Thrombotic events remain a major driver of mortality and morbidity among patients with systemic lupus erythematosus.

Tumor necrosis factor inhibitor therapy in patients with psoriatic arthritis does not appear to accelerate weight gain beyond expected age-related trends, according to findings from a retrospective cohort study.

Cross-sectional testing shows reduced cardiorespiratory fitness in psoriatic arthritis, with disease activity and adiposity linked to lower VO2peak and self-reported activity linked to higher fitness.

JAK inhibition with tofacitinib increased lower limb muscle volume; strength and function did not improve in rheumatoid arthritis.

Advanced drug delivery systems may improve outcomes in gout and hyperuricemia by enhancing targeting and tolerability.

Adrenal crisis was rare after glucocorticoid taper in children with nephrotic syndrome or juvenile idiopathic arthritis.

Real-world evidence indicates that hereditary angioedema with normal C1 inhibitor is frequently hormone sensitive.

Patients and prescribers often have mismatched expectations about pain management following total hip or knee replacement surgery.

Patients with interstitial pneumonia with autoimmune features (IPAF) have both lung disease and signs of autoimmunity.

Distinct gut bacteria may play a role in driving lung damage among people with systemic sclerosis (SSc).