Urology

Ben Challacombe |Consultant Urological Surgeon, Guy’s and St Thomas’ NHS Foundation Trust and King’s College London, UK. Having spent over 10 years in your current role with Guy’s and St Thomas’, what initially sparked your interest in urology and has pushed you to reach your established position today?

Bladder cancer (BC) is the fourth most common malignancy in males and shows high prevalence and mortality rates worldwide despite improvements in its management.

Testicular seminomas are the most common type of testicular germ cell tumours. It typically affects young males between the ages of 30–55 years. Because of its high sensitivity to chemotherapy and radiotherapy, these tumours have high cure rates.

Polyacrylamide hydrogel (PAHG) Bulkamid® (Axonics, Irvine, California, USA) was introduced in Europe as a promising periurethral bulking agent for the treatment of female stress and mixed urinary incontinence in 2006.

EMJ spoke to Christopher Chapple about his role as Secretary General of the European Association of Urology (EAU)…

As part of the 37th Annual European Association of Urology (EAU) Congress, this symposium presented key data from the CLEAR study: a Phase III randomised controlled trial evaluating lenvatinib plus pembrolizumab versus sunitinib in patients with advanced renal cell carcinoma (RCC) in the first-line (1L) setting.

At least 60% of females worldwide will experience at least one UTI in their lifetime.4 An array of pathogenic bacteria, both gram-negative and gram-positive, can cause the infections, although in uUTIs, Escherichia coli (E. coli) is the predominant pathogen.

Imaging has a pivotal role in the staging of primary prostate cancer, as well as in determining optimal management strategies.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition of unknown aetiology. Symptoms can vary but there is typically pelvic pain or discomfort perceived to be related to the urinary bladder, usually accompanied by other urinary symptoms such as the persistent urge to void or frequency.

Prostate cancer varies at initial diagnosis and in its progression, with non-metastatic and metastatic presentations that may or may not respond to ADT (Figure 1).

Prasanna Sooriakumaran | Lead for Urology and Consultant Urological Surgeon, Cleveland Clinic London, UK; Consultant Urological and Robotic Surgeon, University College London Hospitals; Honorary Senior Clinical Researcher, University of Oxford, UK.

Isolated renal hydatid disease, caused by the larvae of the parasitic tapeworm Echinococcus granulosus is a rare phenomenon and accounts…

In this case, retrograde ureteroscopy with holmium laser on the retained suture proved an effective treatment in the removal of the stent.

Penile squamous cell carcinoma (SCC) is a rare malignancy associated with human papillomavirus and immunosuppression.

In the light of their journey through urological texts, the authors propose that the prostate screening collaborating with PSA measurements should continue..

BPH is the most common non-cancerous neoplasm of ageing males,1 increasing in incidence with age. The prevalence of BPH has been estimated…

At the authors’ institution, they prefer to use the robotic approach as it allows the trainees to hone their skills for other robotic procedures such as partial nephrectomies, nephroureterectomies, and pyeloplasties.

Currently, the exact mechanism underlying EMPD is unknown, but two widely known theories exist, namely the epidermotropic and transformation theories.

Obesity (BMI: >30 kg/m2) has reached epidemic proportions, both globally as well as locally in the Caribbean region, without discrimination against age, sex, race, socioeconomic, and educational levels.

In this study, using transurethral and biopsy tissue and plasma samples, the robustness of a malignancy index that not only discriminates PCa from non–PCa but is also able to predict tumour stage is also examined.

Approximately 10–15% of the general population is affected by urolithiases at least once in their lifetime. Having a giant urinary bladder stone is a particularly rare condition and its development is usually associated with disorders that promote urinary stasis.

Prokar Dasgupta  | Foundation Professor of Surgery, King’s Health Partners, King’s College London; Honorary Consultant Urologist…

Irreversible electroporation (IRE) is emerging as a new method of soft tissue ablation, with applications including focal therapy in patients…

Benign prostatic hyperplasia (BPH) is a chronic age-related condition associated with lower urinary tract symptoms (LUTS). Although conservative…