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Optical Coherence Tomography Angiography in Multiple Sclerosis
9
Mins
April 2024
This study aims to evaluate changes in retinal microvasculature in patients with multiple sclerosis (MS) by means of optic coherence…
Read more
9
Mins
19th April 2024
Optical Coherence Tomography Angiography in Multiple Sclerosis
This study aims to evaluate changes in retinal microvasculature in patients with multiple sclerosis (MS) by means of optic coherence…
8
Mins
19th March 2024
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Masterclass Event Summary
A masterclass initiated, organised, and funded by UCB, sought to advance understanding and expertise of myelin oligodendrocyte…
8
Mins
15th March 2024
Impact of Non-Seizure Symptoms in Dravet Syndrome and Lennox-Gastaut Syndrome
Non-seizure symptoms in Dravet and Lennox-Gastaut syndromes can affect speech, gait, appetite, mood, development, and sleep and impact…
5
Mins
15th February 2024
Interview: Chia-Chun Chiang
My father, a dedicated neurosurgeon, played a significant role in my choice. He tirelessly shared stories of the lives he had saved…
8
Mins
14th December 2023
Spasticity Following Acute Stroke
Many patients experience impairment following a stroke, including motor or cognitive impairment, urinary incontinence, dysphagia…
8
Mins
14th December 2023
Tackling Becker Muscular Dystrophy
First described by German physician Peter Emil Becker in the 1950s, Becker is an X-linked genetic recessive disorder. Like Duchenne…
7
Mins
20th November 2023
A Review of Oral Fixed-Dose Sodium Phenylbutyrate and Ursodoxicoltaurine in People with Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is estimated to affect approximately 300,000 individuals worldwide…
11
Mins
4th October 2023
Lennox–Gastaut Syndrome: Challenges in Diagnosis – Interviews with Two Key Opinion Leaders
Lennox–Gastaut syndrome (LGS) is a severe childhood-onset epilepsy syndrome that can be challenging to identify due to its heterogeneous and..
13
Mins
14th September 2023
The Unspeakable Disease: A Tale of Two Siblings
The deficiency of arylsulfatase A due to the mutations in the ARSA gene is the cause of a rare inherited lysosomal storage disease…
6
Mins
14th September 2023
Assessment of Post-Traumatic Stress Disorder in Patients Who Recovered from COVID-19
It is essential to address psychological health, particularly post-traumatic stress disorder (PTSD), among patients who have recovered from…
11
Mins
15th August 2023
Focal Onset Seizures: New Treatment Options in The Clinical Practice
Carreño began by discussing the spectrum of uncontrolled epilepsies. They stressed that uncontrolled epilepsy does not necessarily…
9
Mins
15th August 2023
A Spotlight on Friedreich Ataxia: Optimising the Patient Journey from Diagnosis to Disease Management
Boesch explained that in the European Union (EU), a rare disease is defined as a disease that affects less than one person in 2,000…
6
Mins
15th August 2023
Development of the Clinical Myotonia Rating Scale and a Mexiletine Prescribing and Monitoring Algorithm for Patients with Non-Dystrophic Myotonia
In the rare neuromuscular disorders classed as NDM, muscle stiffness (myotonia) is the major symptom and is defined by a delayed muscle…
8
Mins
15th August 2023
Mitochondrial DNA Maintenance Disorders: Impact of Impaired Deoxynucleoside Triphosphates Metabolism
The maintenance of mitochondrial DNA (mtDNA) is dependent upon several nuclear gene-encoded proteins including enzymes forming the…
4
Mins
15th August 2023
Interview: Hugh Selsick
My science degrees were pivotal in fuelling my passions and setting out my career path. During my undergraduate physiology degree…
7
Mins
15th August 2023
Cerebrotendinous Xanthomatosis: A Clinical Series Illustrating the Radiological Findings
Cerebrotendinous xanthomatosis (CTX) is a unique disease with an autosomal recessive inheritance, occurring due to the accumulation…
7
Mins
15th August 2023
Study for Assessment of Mental Health in Survivors of COVID-19
COVID-19 infection was first reported in December 2019 in Wuhan, China, as a pneumonia outbreak presenting with fever…
6
Mins
15th August 2023
Lymphoma of Nervous System or the Great Imitator in Neurology
Primary and secondary lymphoma of the central nervous system (CNS) is a rare case of non-Hodgkin lymphoma. The World…
7
Mins
13th July 2023
Isolated Sacral Tuberculosis: A Rare Case Report and
Literature Review
Tuberculosis (TB) is an infectious disease caused by the transmission of Mycobacterium tuberculosis bacillary complex…
8
Mins
3rd May 2023
Editor's Pick: Orthostatic Hypotension and Concomitant Paraneoplastic Syndromes: A Case Report
Paraneoplastic autonomic neuropathy is a syndrome with an unclear aetiology and wide array of symptoms. Some studies have identified a strong autoimmune component in the development of paraneoplastic autonomic neuropathy, though some aetiologies are non-immune in nature.
2
Mins
2nd March 2023
From CoNFLict to Confidence: Solving a Diagnostic Dilemma Using Neurofilament Light – A Case Report
Measurement of fluid biomarkers of neurodegeneration is an emerging approach offering improved diagnostic accuracy of neuropsychiatric conditions, particularly for atypical presentations. This article reports a case where the diagnosis of delirium with dementia was revised based on biomarker analysis, enabling treatment of a primary mood disorder with resolution of recurrent disabling psychiatric symptoms.
8
Mins
20th February 2023
Benzodiazepines in Dementia: Review of Clinical Evidence
In the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), Alzheimer’s disease (AD [named after the German psychiatrist and neuropathologist, Alois Alzheimer, who first described it]), is considered as a major or mild neuro-cognitive disorder…
5
Mins
17th February 2023
Hearts are NOT Made to Be Broken: Expert Opinion on Amyloid Light-Chain Cardiac Amyloidosis
Amyloid light-chain (AL) amyloidosis is a rare systemic disease caused by plasma cell dyscrasia. These plasma cells produce excess Ig light chains, which can misfold, aggregate, and deposit in tissues, resulting in toxicity and organ dysfunction. The heart is among the most commonly affected organs and cardiac involvement is associated with significantly worse outcomes.
11
Mins
31st January 2023
The Efficacy and Safety of SARS-CoV-2 Vaccinations in People with Multiple Sclerosis
While people with multiple sclerosis (MS) are not more likely to contract COVID-19, the incidences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19-related complications may be higher for people with MS who have comorbidities or who are taking certain disease modifying therapies (DMT).
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