European Archives - Page 456 of 1108 - European Medical Journal

EMJ

MRI Response Assessment in Patients with Glioblastoma Treated with Dendritic Cell-Based Immunotherapy

In glioblastoma (GB), patients’ reliable response assessment criteria are crucial in order to accurately compare the responsiveness of different therapies in clinical trials, and to differentiate between therapy-induced changes and true tumour progression.

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Highlights from EAN 2022

This year’s European Academy of Neurology (EAN) Congress offered a plethora of sessions in different areas of neurology.

EMJ

Brain Tumour-Related Epilepsy: Impact of Grading and Treatments in a Cohort of Molecularly Defined Lower-Grade Gliomas

Brain tumour-related epilepsy (BTRE) is associated with diffuse lower-grade gliomas (DLGG) in up to 70–90% of cases.

Einar August Høgestøl

EAN Congress Interview - Einar August Høgestøl

Einar August Høgestøl | Associate Professor, Department of Psychology, University of Oslo, Norway; Doctor-in-Training, Department of Neurology, Oslo University Hospital, Norway; 2022. Author of the Best Presentation in Basic Neurology at the European Academy of Neurology (EAN) Tournament for Neurologists in Training.

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Improving The Management of Non-dystrophic Myotonia to Benefit Care Delivery and Improve Patient Outcomes

Non-dystrophic myotonias (NDM) are a group of rare muscle disorders with a reported prevalence of 0.75−1.7 per 100,000 population (Figure 1).

EMJ

Seizure Forecasting with Non-invasive and Minimally Invasive Mobile Devices: The Epilepsy Foundation’s My Seizure Gauge Study

Seizure unpredictability is consistently reported as one of the most disabling aspects of living with chronic epilepsy. Reliable forecasting systems could have far-reaching consequences for patients, from allowing protection at times of high seizure risk to improving confidence during everyday life at times of low seizure risk.

EMJ

Prefrontal Transcranial Direct Current Stimulation in Patients with Disorders of Consciousness: A Multicentre, Randomised, Double-Blind, Sham-Controlled Clinical Trial

Transcranial direct current stimulation (tDCS) applied over the left dorsolateral prefrontal cortex has shown to transiently improve the level of consciousness of severely brain-injured patients in disorders of consciousness, and seems to be effective especially for patients in minimally conscious state (MCS) compared with patients in unresponsive wakefulness syndrome.

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Sex-Related Differences in Symptoms Among Patients Presenting with Acute Stroke: A Systematic Review and Meta-analysis

Recognising acute stroke symptoms is crucial in providing timely treatment. However, evidence suggests that females often experience unique symptoms compared with males, resulting in delays to seeking medical attention and treatment.

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Never Too Late to Treat NMDAR Encephalitis: A Paediatric Case Report and Review of Literature

Dysfunction of N-methyl-D-aspartate receptors (NMDAR) have been proposed as the aetiology for multiple neuropsychiatric diseases. While overactivity of NMDA receptors causing excitotoxicity has been implicated in epilepsy, dementia, and stroke, low activity may produce symptoms resembling those of schizophrenia.

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Haemodynamic Determinants of Supine Hypertension in Neurogenic Orthostatic Hypotension

Patients with classic orthostatic hypotension (cOH) suffer from an abnormally large blood pressure (BP) fall upon standing due to baroreflex dysfunction. cOH, particularly in the absence of BP-lowering drugs, often has a neurogenic cause (neurogenic orthostatic hypotension [nOH]).