European Archives - Page 552 of 1590 - European Medical Journal

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EMA grants accelerated review to Gilead’s PrEP drug

The EMA is set to perform accelerated reviews of Gilead Sciences’ applications for its twice-yearly injectable for HIV prevention.

Improving Hepatocellular Carcinoma Detection With Targeted Screening

To improve screening efficiency, it is crucial to identify patients with elevated hepatocellular carcinoma risk while sparing low-risk individuals from unnecessary procedures.

Simple Blood Test Uses Placental Growth Factor to Predict Preterm Birth Risk

A simple blood test measuring placental growth factor (PlGF) during pregnancy could identify those at risk of early preterm birth.

Spinal Degeneration Common in Young Patients with Psoriatic Arthritis

New research reveals that nearly 40% of young PsA patients develop degenerative disc disease (DDD), with age, male sex, and diabetes as key risk factors. The study also found that inflammatory back pain does not reliably distinguish between axial PsA and spinal degeneration, complicating diagnosis and treatment.

Poor Sleep Quality Linked to Severe PMS Symptoms in Young Women

New research suggests that poor sleep quality worsens PMS symptoms, with nearly 50% of participants experiencing severe symptoms. The study highlights the crucial role of sleep in PMS management, suggesting that better sleep could help reduce mood swings, fatigue, and anxiety.

Link Between Tumour-Infiltrating Lymphocytes and Breast Cancer Survival

Study finds tumour-infiltrating lymphocytes linked to survival in early ERBB2-positive breast cancer, suggesting treatment de-escalation may be possible

Gut Microbiota Maturation Disrupted in Infants with Cystic Fibrosis

Findings revealed that microbiota maturation in cystic fibrosis is delayed, preventing the establishment of a stable, adult-like community.

Non-Invasive Markers Could Differentiate Complicated Appendicitis Early

Researchers have identified key biomarkers that could help distinguish between uncomplicated and complicated appendicitis, allowing for earlier and more accurate diagnosis. The study found that Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV), and appendix diameter are reliable indicators of appendicitis severity.

New Study Uncovers Key Mechanisms in Psoriasis

Recent findings indicate that c-Rel expression is upregulated in psoriatic skin lesions and decreases following treatment.

Urinary DNA Test Shows High Accuracy for Bladder Cancer

Ultimately, these findings highlight the potential for urinary DNA methylation testing to improve early detection and diagnosis of bladder cancer.