Dermatology

Cutaneous ulcers present a significant challenge in the management of chronic graft-versus-host disease (cGVHD), a complication that affects patients who have undergone allogeneic hematopoietic cell transplantation.

A recent nationwide study conducted in Italy provides important insights into how body weight may influence the efficacy of JAK inhibitors in treating moderate-to-severe atopic dermatitis (AD).

The growing body of research on the gut-skin axis and human microbiome has sparked increasing interest in microbiome-modulatory agents as potential treatments for acne vulgaris.

Dermoscopy traits of adnexal tumors in patients with darker skin tones may closely mimic features of malignant neoplasms, creating significant diagnostic uncertainty for clinicians.

Immune checkpoint inhibitors (ICIs) have transformed cancer care but can trigger immune-related adverse events such as psoriasis, complicating treatment decisions.

The use of beta-blockers has dramatically changed the management of infantile hemangiomas, with a significant increase in active treatment decisions at tertiary referral centers, according to a new retrospective cohort study.

A new international study has developed and validated prognostic models using novel inflammatory markers to predict in-hospital mortality in patients with drug reaction with eosinophilia and systemic symptoms (DRESS), a rare but life-threatening hypersensitivity reaction.

Gluten-related skin conditions may extend well beyond the classic dermatitis herpetiformis, according to a new overview of gluten-induced dermatoses that highlights diagnostic and therapeutic pathways for clinicians.

Climate change is severely affecting the physical and psychological health of reproductive-age women living in Bangladesh’s coastal communities, according to a new study.

Skin cancer risk remains high in patients with xeroderma pigmentosum, including rare long-term survivors, according to a newly reported case of squamous cell carcinoma (SCC) in a 55-year-old woman with the condition.

Primary care physicians are pivotal in the early recognition and referral of rare eosinophilic diseases, such as hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA), which remain underdiagnosed despite their serious multisystem impact.

A nationwide study of basal cell carcinoma (BCC) excisions in Denmark found that hospital-based specialists have significantly lower odds of incomplete removal than their practice-based peers, raising important questions about treatment setting and provider expertise.

Patients with autoimmune skin diseases (ASDs) may have improved survival following cancer treatment, according to a large population-based study, suggesting a possible immunologic advantage in oncologic outcomes.

A new perspective on atopic dermatitis suggests that disruptions to the skin’s microbial ecosystem and routine bathing practices may play a larger role in the disease’s origin and progression than previously recognized.

Emerging immunotherapies are transforming the treatment landscape for pemphigus and bullous pemphigoid, two distinct autoimmune blistering skin diseases marked by pathogenic autoantibodies and significant patient burden.

In a compelling case that underscores the complexity of biologic therapies, a patient with hidradenitis suppurativa (HS) developed adalimumab-induced pustular psoriasis, which was successfully treated with guselkumab.

Acne has emerged as a frequent and clinically relevant side effect in patients with inflammatory bowel disease (IBD) treated with JAK inhibitors, according to the largest international retrospective cohort study to date on this adverse event.

A growing number of anaphylaxis cases linked to cashew nuts, especially in children, combined with an unexpected frequency of almond-induced reactions in adults, signals a shift in the landscape of tree nut allergies, according to new data from the European Anaphylaxis Registry.

Autistic individuals face major barriers in dermatologic care, and a new review urges systemic reform to advance equity and improve outcomes.

Whole body vibration (WBV) training may trigger itch and erythema in a significant portion of users, with side-to-side vibration devices posing a higher risk, according to a new multicenter study.

New research suggests that Mohs micrographic surgery (MMS) alone may lead to lower recurrence rates than when combined with photodynamic therapy (PDT) in treating locally advanced basal cell carcinoma (laBCC), particularly in non-aggressive subtypes.

A new study reveals major differences in cosmetic laser practices across US dermatologists, plastic surgeons, and medical spas. Key findings raise patient safety concerns and emphasize the importance of specialized training.

Psoriasis in pregnancy and lactation presents critical challenges for clinical management, according to a new review aimed at dermatologists and healthcare professionals.

A randomized controlled trial reveals that topical timolol may offer an effective and non-invasive solution to improve the appearance of immature scars following mammoplasty surgery.

A new dermatology study offers compelling evidence that targeted lipid supplementation can restore the skin barrier in adults with a history of atopic dermatitis, outperforming commonly used emollients.

As cannabis use continues to surge across the United States, a growing body of research is shedding light on its underrecognized dermatological consequences.

In a significant advancement for the management of prurigo nodularis, a chronic and debilitating skin condition, a new systematic review highlights the promise of emerging biologic and targeted therapies that directly address the disease’s immune and neurogenic drivers.

Eye drop pain during routine exams may offer more than momentary discomfort, it could serve as an early marker of dry eye syndrome, according to a new study that reveals the link between pain sensitivity and ocular surface health.

Non-genetic factors such as age, allergies, smoking, and prior history of angioedema may significantly increase the risk of angioedema in patients taking ACE inhibitors or angiotensin receptor blockers, according to new pharmaco-epidemiological research.

New analysis shows promising repigmentation with JAK inhibitors in vitiligo, especially in combination with UVB. Safety and long-term outcomes remain key research needs.

Dermatological conditions in polar environments are gaining new attention as research missions to the Arctic and Antarctic expand.

Persistent acne scarring remains a major concern for patients and clinicians alike, with many individuals turning to invasive procedures in search of effective relief.

Biologic therapies targeting interleukin (IL)-17 and IL-23 have transformed the treatment landscape for plaque psoriasis, but questions remain about how these therapies perform in elderly patients compared to younger adults.

In dermatology research, the use of race and ethnicity as population descriptors has come under increasing scrutiny, with experts questioning whether these broad categories obscure more than they reveal about human health.

Healthcare professionals treating conditions such as peripheral neuropathy, wound ulcers, or radiation dermatitis now have fresh, evidence-based guidance on the use of photobiomodulation (PBM) therapy.

Radiologic imaging in high-risk cutaneous squamous cell carcinoma (cSCC) has proven more valuable than previously recognized, uncovering unexpected findings in nearly half of patients and prompting significant changes in treatment, according to a major retrospective study.

Opioid prescribing trends following outpatient surgery have seen a marked decline over the last decade, according to new U.S. claims data, signaling a nationwide shift in post-operative pain management across multiple surgical specialties.

A new systematic review and meta-analysis sheds light on the evolving understanding of body dysmorphic disorder (BDD), presented in line with recent psychiatric research updates.

Oncolytic viral therapy may offer new hope for patients with nonmelanoma skin cancers and cutaneous lymphomas, according to a new systematic review of published and ongoing research.

In a new network meta-analysis evaluating treatments for vitiligo, researchers have identified the most effective combinations of phototherapy and topical therapies, offering clinicians fresh insights into optimizing patient outcomes.

A novel combination of rhinoshave and fractional ablative CO2 laser therapy is proving to be a safe and effective approach for treating pronounced rhinophyma, offering precise contouring with minimal complications and high patient satisfaction, according to a new study.

Biologic therapies significantly reduce the risk of major adverse cardiovascular events (MACEs) in patients with psoriasis and psoriatic arthritis (PsA), offering potential heart health benefits beyond skin and joint relief.

A clinical trial has assessed whether 3D total-body photography (TBP) combined with sequential digital dermoscopy imaging (SDDI) enhances melanoma detection in high-risk patients.

A novel high-intensity, high-frequency ultrasound device has demonstrated significant effectiveness in reducing facial acne scars, according to a new clinical study.

Blood plasma, fibrinogen, and fibrin have long been explored for their role in skin tissue engineering and dermatological treatments, with promising preclinical results—but clinical adoption remains limited.

Body-focused repetitive behaviors (BFRBs), including skin-picking, hair-pulling, and nail-biting, significantly impact quality of life, yet access to effective treatments remains a challenge.

AI and machine learning (ML) are reshaping dermatopathology by improving diagnostic accuracy, enabling predictive analytics, and optimizing workflows.

Dietary recommendations for psoriasis on Instagram have been analyzed in a new study, which found that nearly all posts lack scientific credibility, with most advice coming from unqualified individuals.

A recent phase 3 open-label extension study has demonstrated that delgocitinib cream is both safe and effective for long-term management of chronic hand eczema (CHE) in adults.

Increasing diversity in research, from basic science to clinical trials, remains essential for advancing equitable healthcare outcomes.

Achieving comprehensive education in skin of colour (SoC) dermatology remains a challenge in residency programs, with significant disparities in exposure to diverse skin tones across institutions.

Patients with severe alopecia areata (AA) may experience prolonged hair regrowth even after discontinuing treatment with bempikibart, according to findings from the SIGNAL-AA phase 2a study presented at the American Academy of Dermatology (AAD) Annual Meeting.

A phase 2 clinical trial has demonstrated that a once-daily oral tyrosine kinase 2 (TYK2) inhibitor significantly improves symptoms in adults with moderate to severe plaque psoriasis, achieving high clearance rates with a safety profile comparable to placebo.

A new analysis of five clinical trials confirms that dupilumab significantly improves lichenification in patients with moderate to severe atopic dermatitis (AD) across all ages and racial backgrounds.

Artificial intelligence (AI) is becoming a key tool in skin cancer diagnosis, but patient acceptance remains a critical aspect of its implementation.

A recent study has revealed that adult survivors of childhood cancer face a significantly elevated risk of developing melanoma, underscoring the necessity for vigilant long-term monitoring and tailored preventive strategies.

A recent global retrospective cohort study has demonstrated that dupilumab, a monoclonal antibody used to treat atopic dermatitis (AD), offers a favorable cardiometabolic safety profile compared to traditional systemic agents such as methotrexate and cyclosporine.

The U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for Zabalafin Hydrogel, a novel therapy designed to treat mild to moderate atopic dermatitis (AD) comprehensively.

Long-term data reveal that bimekizumab, a dual IL-17A and IL-17F inhibitor, provides sustained symptom control for patients with hidradenitis suppurativa (HS).

A recent meta-analysis suggests that statin use is associated with improved survival outcomes in patients with cancer undergoing immune checkpoint inhibitor (ICI) therapy.

A recently published review examined the impact of obesity, diabetes, and smoking on surgical outcomes for patients with hidradenitis suppurativa (HS).

Recent advancements in artificial intelligence (AI) are reshaping dermatology, particularly in diagnosing skin diseases like skin cancer.

Survivors of blood or marrow transplants (BMT) face a significantly higher risk of developing cutaneous malignant neoplasms, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma, according to a recent cohort study.

The University of Pennsylvania Health System has revealed that targeted educational interventions can significantly enhance healthcare workers’ understanding and management of regulated medical waste (RMW) in a recent study.

A new retrospective study has shed light on the incidence of cutaneous pyogenic granulomas (PGs) by age, sex, and anatomical location.

Understanding why some patients with melanoma respond to immunotherapy while others do not has remained a critical challenge for precision medicine.

A recent clinical trial has shown promising results in treating severe, active vitiligo through a combination of oral medication and phototherapy, offering new hope for managing this challenging condition.

Fixed-combination topical therapies show improvements in acne within the first 4 weeks of treatment, according to new data compiled from pivotal clinical trials.

A groundbreaking clinical trial has provided valuable insights into the management of dermatoporosis, a condition characterized by chronic extracellular matrix (ECM) degradation leading to skin atrophy and fragility.

A recent large-scale study published in a dermatology journal provides important insights into the cardiovascular safety of biologic therapies for patients with psoriasis or psoriatic arthritis (PsA).

A new systematic review has shed light on the safety of beta blockers for treating PHACE syndrome, addressing concerns about stroke risk in patients with cerebrovascular and cardiovascular anomalies.

A recent study has highlighted metformin’s potential role in reducing the risk of non-melanoma skin cancers (NMSC), offering intriguing possibilities for dermatological and oncological care.

A new study reveals that patients with cutaneous lupus erythematosus (CLE) face significantly higher risks of atherosclerotic cardiovascular disease (ASCVD) compared to the general population.

A recent study has uncovered promising advancements in the fight against Stage II melanoma by introducing a novel biomarker technique, immune Förster resonance energy transfer (iFRET).

An epidemiological study has shed light on the primary risk factors driving Merkel cell carcinoma (MCC), a rare but aggressive form of skin cancer.

Patients with moderate-to-severe atopic dermatitis who did not initially meet response criteria for lebrikizumab at 16 weeks can still achieve improvements with continued therapy, according to a recent clinical trial analysis.

The VISIBLE trial sets a benchmark for diversity in psoriasis research, achieving rapid enrollment and valuable data for patients with skin of color.

The most commonly treated pediatric cosmetic conditions included hypertrophic and traumatic scars, acne, axillary and facial hyperhidrosis.

This study highlights the importance of recognizing physiologic volar melanotic macules in clinical practice, particularly in individuals with skin of color

An international expert panel of 43 dermatologists has established an expert consensus on the off-label use of low-dose oral minoxidil (LDOM) for treating hair loss.

In an effort to improve psoriasis research, the VISIBLE clinical trial has made significant strides in diversity, enrolling participants with skin of color (SoC) at an accelerated rate.

A recent cohort study involving 144,447 participants has found a crucial threshold in melanoma risk for tumors with a Breslow thickness between 0.8 and 1.0 mm.

Survivors of cutaneous melanoma (CM) face a 57% increased risk of developing second primary malignancies (SPMs) compared to the general population, according to groundbreaking research from a recent analysis of SEER database data spanning two decades.

Navigating treatment options for hidradenitis suppurativa (HS) may include consideration of clinic-based deroofing as a more effective and economical choice compared to local excision.

A recent multicenter cohort study reveals that preterm infants are more likely to develop severe forms of infantile hemangiomas (IH), raising concerns about delayed diagnosis and potential scarring risks.

A newly published review sheds light on how the digital revolution is reshaping the field of cosmetic dermatology.

A new study has revealed how the protein Rab7a enhances the activity of TPC2, a cellular channel linked to melanoma, the deadliest form of skin cancer.

A cutting-edge alternative to traditional skin creams offers a promising new approach for treating inflammatory skin diseases.