Dermatology

Melanoma quality of life differs during and after immunotherapy, with fatigue, skin issues, and sexual dysfunction.

Network meta-analysis ranks brucellosis treatment regimens, finding triple-drug combinations outperform widely used dual therapies.

Children with moderate-to-severe generalized pustular psoriasis (GPP) benefit significantly from biologic therapy.

Cutaneous venous malformations (cVMs), rare vascular anomalies marked by progressive vessel dilation, pain, ulceration, and bleeding, may be more prevalent in the US than previously recognized.

Helical tomotherapy combined with paclitaxel demonstrated encouraging survival outcomes with manageable toxicity in patients with cutaneous angiosarcoma.

Adalimumab use in patients with hidradenitis suppurativa (HS) appears safe with appropriate prophylaxis, as no cases of hepatitis B virus (HBV) or tuberculosis (TB) reactivation were observed in a large retrospective analysis.

Dupilumab may provide meaningful relief for patients with chronic kidney disease who experience uremic pruritus and for those with atopic dermatitis complicated by renal impairment, according to a retrospective real-world study.

Oral JAK inhibitors appear effective and safe in the treatment of vitiligo, according to a retrospective study evaluating real-world outcomes in nearly 100 patients.

Children under 12 years with moderate to severe atopic dermatitis experienced varying outcomes with systemic therapies, according to new real-world data from the PEDISTAD registry.

Cutaneous vasculitis in primary Sjögren disease is linked to significantly worse outcomes, particularly when cryoglobulinemic vasculitis is present, according to findings from a large multicenter cohort study.

Patients with psychophysiological skin disorders such as atopic dermatitis, psoriasis, pruritus, and alopecia experience measurable benefits in post-traumatic growth when they receive emotional and informational support, according to new research.

Scalp cutaneous metastases from breast carcinoma may present with varied clinical patterns, and new research highlights distinct dermoscopic features that could aid earlier recognition.

Platelet-rich plasma (PRP) therapy significantly enhances the healing of diabetic foot ulcers compared with standard wound care, according to findings from a randomized controlled trial that assessed both clinical outcomes and histopathological changes.

Scalp micropigmentation (SMP) demonstrated effective and safe cosmetic improvement for patients with localized alopecia, according to a technical analysis and case series.

A new U.S. analysis of patient experiences with psoriatic disease highlights significant diagnostic delays, emotional burden, and potential underdiagnosis of psoriatic arthritis (PsA).

Adults with psoriasis may be more likely to also have chronic bronchitis, according to new U.S. population-based findings.

Children with erythropoietic protoporphyria (EPP) frequently endure severe, unexplained pain triggered by sunlight or artificial light exposure, yet diagnosis is often delayed despite distinctive clinical features.

Stiffness and swelling were identified as the most reliable clinical indicators distinguishing psoriatic arthritis from non-inflammatory musculoskeletal conditions in patients with psoriasis, according to a retrospective review from a combined rheumatology-dermatology clinic.

Oral probiotics may offer therapeutic benefits for patients with acne, according to a new systematic review and meta-analysis of randomized trials.

Chronic pruritus, the hallmark symptom of atopic dermatitis (AD), is driven by a relentless itch–scratch cycle that can persist despite clinical improvements from conventional therapies.

Patients with psoriasis initiating biologic therapy, particularly tumor necrosis factor (TNF) inhibitors, may have a reduced long-term risk of developing primary malignancies compared with biologic-naïve individuals, according to a large retrospective cohort study.

Robotic-assisted techniques could one day enhance the precision of Mohs micrographic surgery (MMS) for rare cutaneous sarcomas such as dermatofibrosarcoma protuberans (DFSP), but current technology remains ill-suited for skin-level applications, according to recent research.

The clinical legitimacy of topical steroid withdrawal (TSW) remains a point of contention among dermatologists, according to new survey data from Australian specialists.

Real-world data on atopic dermatitis (AD) treatment has revealed that while current treat-to-target (T2T) strategies are feasible, several clinical targets may require refinement to better reflect meaningful outcomes.

A recent cross-sectional study sheds light on the knowledge, perceptions, and practices surrounding skin-lightening products (SLPs) among female medical students.

Therapeutic options for pediatric psoriasis are growing rapidly, with biologics and oral small molecules now playing a central role in modern treatment.

A recent systematic review of Merkel cell carcinoma (MCC) treatment in solid organ transplant (SOT) recipients reveals an urgent need for clearer treatment guidelines.

Cutaneous ulcers present a significant challenge in the management of chronic graft-versus-host disease (cGVHD), a complication that affects patients who have undergone allogeneic hematopoietic cell transplantation.

A recent nationwide study conducted in Italy provides important insights into how body weight may influence the efficacy of JAK inhibitors in treating moderate-to-severe atopic dermatitis (AD).

The growing body of research on the gut-skin axis and human microbiome has sparked increasing interest in microbiome-modulatory agents as potential treatments for acne vulgaris.

Dermoscopy traits of adnexal tumors in patients with darker skin tones may closely mimic features of malignant neoplasms, creating significant diagnostic uncertainty for clinicians.

Immune checkpoint inhibitors (ICIs) have transformed cancer care but can trigger immune-related adverse events such as psoriasis, complicating treatment decisions.

The use of beta-blockers has dramatically changed the management of infantile hemangiomas, with a significant increase in active treatment decisions at tertiary referral centers, according to a new retrospective cohort study.

A new international study has developed and validated prognostic models using novel inflammatory markers to predict in-hospital mortality in patients with drug reaction with eosinophilia and systemic symptoms (DRESS), a rare but life-threatening hypersensitivity reaction.

Gluten-related skin conditions may extend well beyond the classic dermatitis herpetiformis, according to a new overview of gluten-induced dermatoses that highlights diagnostic and therapeutic pathways for clinicians.

Climate change is severely affecting the physical and psychological health of reproductive-age women living in Bangladesh’s coastal communities, according to a new study.

Skin cancer risk remains high in patients with xeroderma pigmentosum, including rare long-term survivors, according to a newly reported case of squamous cell carcinoma (SCC) in a 55-year-old woman with the condition.

Primary care physicians are pivotal in the early recognition and referral of rare eosinophilic diseases, such as hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA), which remain underdiagnosed despite their serious multisystem impact.

A nationwide study of basal cell carcinoma (BCC) excisions in Denmark found that hospital-based specialists have significantly lower odds of incomplete removal than their practice-based peers, raising important questions about treatment setting and provider expertise.

Patients with autoimmune skin diseases (ASDs) may have improved survival following cancer treatment, according to a large population-based study, suggesting a possible immunologic advantage in oncologic outcomes.

A new perspective on atopic dermatitis suggests that disruptions to the skin’s microbial ecosystem and routine bathing practices may play a larger role in the disease’s origin and progression than previously recognized.

Emerging immunotherapies are transforming the treatment landscape for pemphigus and bullous pemphigoid, two distinct autoimmune blistering skin diseases marked by pathogenic autoantibodies and significant patient burden.

In a compelling case that underscores the complexity of biologic therapies, a patient with hidradenitis suppurativa (HS) developed adalimumab-induced pustular psoriasis, which was successfully treated with guselkumab.

Acne has emerged as a frequent and clinically relevant side effect in patients with inflammatory bowel disease (IBD) treated with JAK inhibitors, according to the largest international retrospective cohort study to date on this adverse event.

A growing number of anaphylaxis cases linked to cashew nuts, especially in children, combined with an unexpected frequency of almond-induced reactions in adults, signals a shift in the landscape of tree nut allergies, according to new data from the European Anaphylaxis Registry.

Autistic individuals face major barriers in dermatologic care, and a new review urges systemic reform to advance equity and improve outcomes.

Whole body vibration (WBV) training may trigger itch and erythema in a significant portion of users, with side-to-side vibration devices posing a higher risk, according to a new multicenter study.

New research suggests that Mohs micrographic surgery (MMS) alone may lead to lower recurrence rates than when combined with photodynamic therapy (PDT) in treating locally advanced basal cell carcinoma (laBCC), particularly in non-aggressive subtypes.

A new study reveals major differences in cosmetic laser practices across US dermatologists, plastic surgeons, and medical spas. Key findings raise patient safety concerns and emphasize the importance of specialized training.

Psoriasis in pregnancy and lactation presents critical challenges for clinical management, according to a new review aimed at dermatologists and healthcare professionals.

A randomized controlled trial reveals that topical timolol may offer an effective and non-invasive solution to improve the appearance of immature scars following mammoplasty surgery.

A new dermatology study offers compelling evidence that targeted lipid supplementation can restore the skin barrier in adults with a history of atopic dermatitis, outperforming commonly used emollients.

As cannabis use continues to surge across the United States, a growing body of research is shedding light on its underrecognized dermatological consequences.

In a significant advancement for the management of prurigo nodularis, a chronic and debilitating skin condition, a new systematic review highlights the promise of emerging biologic and targeted therapies that directly address the disease’s immune and neurogenic drivers.

Eye drop pain during routine exams may offer more than momentary discomfort, it could serve as an early marker of dry eye syndrome, according to a new study that reveals the link between pain sensitivity and ocular surface health.

Non-genetic factors such as age, allergies, smoking, and prior history of angioedema may significantly increase the risk of angioedema in patients taking ACE inhibitors or angiotensin receptor blockers, according to new pharmaco-epidemiological research.

New analysis shows promising repigmentation with JAK inhibitors in vitiligo, especially in combination with UVB. Safety and long-term outcomes remain key research needs.

Dermatological conditions in polar environments are gaining new attention as research missions to the Arctic and Antarctic expand.

Persistent acne scarring remains a major concern for patients and clinicians alike, with many individuals turning to invasive procedures in search of effective relief.

Biologic therapies targeting interleukin (IL)-17 and IL-23 have transformed the treatment landscape for plaque psoriasis, but questions remain about how these therapies perform in elderly patients compared to younger adults.

In dermatology research, the use of race and ethnicity as population descriptors has come under increasing scrutiny, with experts questioning whether these broad categories obscure more than they reveal about human health.

Healthcare professionals treating conditions such as peripheral neuropathy, wound ulcers, or radiation dermatitis now have fresh, evidence-based guidance on the use of photobiomodulation (PBM) therapy.

Radiologic imaging in high-risk cutaneous squamous cell carcinoma (cSCC) has proven more valuable than previously recognized, uncovering unexpected findings in nearly half of patients and prompting significant changes in treatment, according to a major retrospective study.

Opioid prescribing trends following outpatient surgery have seen a marked decline over the last decade, according to new U.S. claims data, signaling a nationwide shift in post-operative pain management across multiple surgical specialties.