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Neddylation and Hepatic Zonation: Insights Into Liver Metabolism and Diseases
1
Mins
June 2025
The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along the lobule…
Read more
2
Mins
28 May 2019
Neutrophil-to-Lymphocyte Ratio and Corticosteroid Response in Alcoholic Hepatitis
Treatment of alcoholic hepatitis with corticosteroids remains controversial, with recent studies indicating only a 28-day survival benefit…
1
Mins
31 May 2018
Resolution of Ascites, Hepatic Encephalopathy, and Variceal Bleeding in Patients with Hepatitis C Virus and Decompensated Cirrhosis Who Received All-Oral Direct-Acting Antiviral Treatment
Worldwide, 185 million people are infected with the hepatitis C virus (HCV);1 approximately 12% of these individuals have manifestations of decompensated…
1
Mins
31 May 2018
A Comparison of Renal Function Before and After Treatment of Chronic Hepatitis C Infection in Patients Who Achieve Sustained Virological Response with Direct-Acting Antivirals
Approximately 3 million people have chronic hepatitis C virus (HCV) infection in the USA. However, there are limited data with regard to the effect of…
2
Mins
31 May 2018
OPTIMIS: Real-World Data in Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolisation: Second Interim Analysis
Transarterial chemoembolisation (TACE) is the most common treatment modality for hepatocellular carcinoma (HCC) worldwide, often used to treat cases…
2
Mins
31 May 2018
Acute Liver Failure: Time to Review Our Follow-Up Policy?
Acute liver failure (ALF) is a rare but serious clinical condition resulting from sudden, massive loss of hepatic parenchyma and metabolic functions.
2
Mins
31 May 2018
Monocyte-Derived Hepatocyte-Like Cells in Combination with Proteomics Identify a Potential Biomarker for Drug-Induced Liver Injury by Diclofenac
Drug-induced liver injury (DILI) is the leading cause of acute liver failure leading to death or requiring transplantation in the European Union (EU) and…
2
Mins
8 Jun 2017
The Importance of Civil Society Involvement in Eliminating Hepatitis C
This is an historic moment for hepatitis C treatment. With the advent of direct-acting antivirals (DAAs), we can now massively reduce the harm from an…
1
Mins
8 Jun 2017
Statins in Cirrhosis and Portal Hypertension
Statins have been used for almost three decades as cholesterol lowering drugs, yet additional effects…
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