Hepatology

A diagnosis of alcohol-related liver disease prompted many patients to reduce or stop drinking, although more than one-third relapsed within three months.

Perineural invasion was found in around one third of patients with intrahepatic bile duct cancer and was linked to poorer overall survival in a meta-analysis.

Women with hepatitis B who experienced ALT flares around childbirth were more likely to achieve earlier HBeAg clearance, a long-term follow-up study found.

Time restricted eating did not improve liver health beyond usual care, with weight loss rather than eating window timing driving reductions in hepatic fat.

Children with paediatric PSC could be stratified into distinct risk groups using early GGT changes, helping predict long-term transplant-free survival.

Alcohol policy preparedness improved globally between 2010 and 2019, but major gaps in national planning and implementation remain.

Liver cancer cases increased in the Netherlands between 2014 and 2022, driven by a rise in MASLD-related disease, while survival remained poor.

A phase 2 trial found that adding low-dose ipilimumab to atezolizumab and bevacizumab did not improve response rates in unresectable liver cancer.