Hepatology

Learn how hepatitis D treatment with bulevirtide affects immune recovery and why long-term therapy may be needed to prevent relapse.

Semaglutide showed a nominally significant benefit versus placebo in a phase 2 MASH trial, while zalfermin plus semaglutide did not meet the primary endpoint.

An investigational GLP-1 dual agonist, DD01, reduced liver fat in adults with MASLD or MASH in a phase 2 trial.

Living donor liver transplant rates recovered after 2009, but disparities persisted, with Black patients continuing to experience lower access.

Gallbladder cancer diagnosis may be improved using circulating cell-free DNA, with a pilot study identifying fragmentomics features that distinguished cancer from non-cancer cases.

Patients who initiated everolimus after liver transplantation had a lower incidence of new cancers in a nationwide French analysis using emulated clinical trials.

A transcriptome-based machine learning model accurately predicted hepatocellular carcinoma recurrence and identified COL2A1 as a potential protective factor, supporting further investigation before clinical implementation.

Microplastics were detected in tumour samples and PVC microplastics may influence radiotherapy response through changes in tumour immunity.