Nephrology

An interpretable machine learning model predicted moderate to severe acute kidney injury in patients with acute pancreatitis using clinical data available within 24 hours of ICU admission.

A prospective cohort study found sarcopenia was independently associated with higher intradialytic hypotension risk among patients receiving haemodialysis.

A study found that miRNA expression was associated with inflammation and reduced physical functional capacity in patients with end stage kidney disease, highlighting miR-16 and miR-206 as potential exploratory biomarkers.

A nationwide cohort study found that biological age acceleration was associated with increased long-term mortality among adults with CKM syndrome stages 0–3.

A study of 112,952 kidney transplant recipients found comparable survival, graft loss and rejection outcomes across immunosuppressive regimens, with age not significantly altering these associations.

New ESC guidelines call for routine CKD screening in patients with CVD, aiming to improve early diagnosis, optimise treatment, and reduce cardiovascular and kidney complications.

Real-world data linked finerenone with higher nephrolithiasis risk than other pharmacological therapies including spironolactone, SGLT2i, and ACEi/ARB in patients with CKD.

A prospective study identified kidney transcriptomic signatures associated with donor diabetes and found that four transcripts attenuated after transplantation into non-diabetic recipients.