Nephrology

A nationwide comparative study shows SGLT2 inhibitors lower long-term chronic kidney disease and acute kidney injury risk compared with GLP-1 receptor agonists.

Melatonin supplementation reduced inflammation and improved lipid profiles in children undergoing chronic haemodialysis, suggesting potential cardiovascular and antioxidant benefits.

A preliminary study suggests a plant-based low-protein diet may improve metabolic and inflammatory parameters and help prevent malnutrition–inflammation complex syndrome in adults with CKD.

Altered serum and urinary bile acids were identified in patients with advanced chronic kidney disease, with specific bile acids associated with declining kidney function.

ERA Registry data show rising kidney replacement therapy incidence and prevalence across Central and Eastern Europe, with wide national variation and limited COVID-19 impact.

Meta-analysis shows neutrophil to lymphocyte ratio is associated with higher risk and progression of diabetic nephropathy, supporting its potential use as an inflammatory biomarker in clinical practice.

In a multivariate Cox proportional hazards model, statin therapy was associated with a 52% relative reduction in the risk of death at 30 days.

39 studies involving 14 300 participants showed that patients with diabetic nephropathy had significantly elevated NLR levels compared to diabetic controls without nephropathy.