Neurology

At the American Academy of Neurology (AAN) Annual Meeting 2025, researchers presented new data from the long-term open-label extension of the Phase II VISIONARY-MS trial, reporting imaging and physiologic findings consistent with improved neuronal function and remyelination in patients with multiple sclerosis (MS).

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, new late-breaking data from a Phase III clinical trial highlighted the efficacy and safety of telitacicept in patients with generalized myasthenia gravis (gMG).

Intravenous fosphenytoin (fPHT) demonstrated rapid and significant pain relief for patients experiencing acute exacerbations of trigeminal neuralgia (TN), according to late-breaking results from the IFT Study presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego.

In a new quasi-experimental study aimed at improving pediatric epilepsy care, researchers have found that tele-nursing significantly reduces maternal anxiety and increases self-efficacy after hospital discharge.

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, new data from the TRAILBLAZER-ALZ clinical trial program highlighted critical risk factors and management strategies for amyloid-related imaging abnormalities (ARIA) in patients with early symptomatic Alzheimer’s disease treated with donanemab.

A genome-wide association study (GWAS) presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego has identified 778 previously unknown genetic variants associated with migraine, shedding new light on the condition’s genetic underpinnings across racial and ethnic groups.

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, researchers presented late-breaking data from the Inspire Study, a trial exploring spinal cord stimulation (SCS) as a holistic treatment for painful diabetic peripheral neuropathy (pDPN).

New results from the Phase III TEMPO-2 trial, presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, indicate that flexible-dose tavapadon significantly improved motor symptoms and daily functioning in adults with early Parkinson’s disease (PD), compared with placebo.

In hospitalized patients with alcohol withdrawal syndrome (AWS), early addition of phenobarbital to lorazepam-based treatment significantly reduces the length of stay and the need for mechanical ventilation compared to dexmedetomidine, according to a new retrospective study conducted in a U.S. tertiary hospital.

At the 2025 American Academy of Neurology (AAN) Annual Meeting, researchers presented compelling new data showing a sharp increase in hospitalizations for cervical artery dissection, a potentially life-threatening cause of stroke, particularly in adults under 50.

The menstrual cycle significantly impacts women’s emotional decision-making and cognitive processing, according to a new EEG study examining approach-avoidance behaviors across different hormonal phases.

Light-to-moderate alcohol consumption may contribute to increased amyloid beta (Aβ) deposition, a hallmark biomarker of Alzheimer’s disease, according to new findings from the ALBION study.

A chronic stroke aphasia study has revealed that significant language recovery can occur even after the initial recovery phase, providing hope for patients who might otherwise feel that recovery is no longer possible.

Neuropsychiatric symptoms are highly prevalent in sporadic Creutzfeldt-Jakob disease (sCJD), with nearly all patients exhibiting behavioral changes early in the disease course, according to a recent study.

A study using machine learning has identified dynapenia, age-related muscle weakness, as a critical but overlooked risk factor for atherosclerotic cardiovascular disease (ASCVD), particularly in females.

A recent study explores the potential of school-based rebound therapy to improve chest health, motor function, and quality of life in children with neurodisability and respiratory issues.

Critical gaps in outpatient ambulatory care utilization among older adults with dementia and mild cognitive impairment (MCI) have been revealed in a new study.

A new systematic review and meta-analysis has assessed whether dual antiplatelet therapy (DAPT) offers significant benefits over single antiplatelet therapy (SAPT) for patients with minor stroke following thrombolysis.

A systematic review of 20 studies has found that deep brain stimulation of the subthalamic nucleus (STN-DBS), a widely used treatment for Parkinson’s disease (PD), may lead to unexpected gait and balance worsening in some patients.

Cognitive decline in relapsing-remitting multiple sclerosis (RRMS) can progress independently of both relapses and MRI-detected disease activity, challenging traditional methods of monitoring MS progression, according to the results of a new study.

A machine-learning classifier designed to assist healthcare professionals in accurately diagnosing the causes of transient loss of consciousness (TLOC) has been introduced in a new study.

Financial challenges faced by family surrogate decision-makers of stroke patients were highlighted in a new study that revealed that nearly half experience moderate to severe concerns about affording stroke-related medical expenses.

A significant association between smoking and the occurrence of cryptogenic ischemic strokes (CIS) in young adults has been published in a new study.

New findings presented at the ACTRIMS Forum 2025 highlight how the latest revisions to the McDonald Criteria could reshape the diagnosis of multiple sclerosis (MS), allowing for earlier identification in patients with radiologically isolated syndrome (RIS) and atypical clinical presentations.

At the ACTRIMS Forum 2025 in West Palm Beach, Florida, researchers unveiled compelling findings on the effects of a 6-month modified Atkins diet (MAD), a less restrictive form of the ketogenic diet, on patients with relapsing multiple sclerosis (MS).

A new analysis of Phase III clinical trial data presented at the ACTRIMS Forum 2025 in West Palm Beach, Florida, suggests that tolebrutinib, a Bruton’s tyrosine kinase inhibitor (BTKi), may be effective in multiple sclerosis (MS) with chronic active lesions.

A troubling trend showing female physicians in the United States are dying by suicide at significantly higher rates than their counterparts in the general population has been exposed in a recent cohort study.

Patients with Parkinson’s disease (PD) are five times more likely to experience chronic pain than their age-matched peers, according to a new study analyzing electronic medical records from over 250 million patients.

A newly identified group of neurons in the brainstem helps regulate meal size by tracking food intake and signaling when to stop eating, according to a study published earlier this month.

High-frequency oscillations (HFOs) as potential biomarkers in Alzheimer’s disease (AD), have been highlighted in a new study, offering insight into how epilepsy affects neurodegeneration.

Engaging in mentally stimulating activities in midlife and late life is linked to a lower risk of Alzheimer’s disease (AD), according to a study from the Chicago Health and Aging Project.

A new randomized clinical trial suggests that once-weekly semaglutide may help reduce alcohol consumption and cravings in adults with alcohol use disorder (AUD).