Respiratory

Chronic lung disease and socioeconomic disadvantage were tied to markedly increased lung cancer risk, among never-smokers in Korea.

US cost-effectiveness analysis showed durvalumab in limited-stage small cell lung cancer improved survival but exceeded thresholds.

Burn pit exposure in veterans, correlated with increased anthracotic pigment burden measured by microscopy in lung tissue biopsies.

CT in alpha-1-antitrypsin deficiency tied airway wall thickness to next-year exacerbations beyond emphysema severity alone overall.

Online behavior change intervention did not increase physical activity in asthma participants however asthma control strengthened.

Residual CFTR function in cystic fibrosis, associated to improved glucose tolerance and insulin secretion in 341 OGTT participants.

In idiopathic pulmonary fibrosis, 12 months of pulmonary rehabilitation increased cerebral oxygenation, VO₂peak, and mood.

After COVID-19 measures eased, flu symptoms aligned with revived winter peaks for RSV and Influenza A.

Sleep quality in chronic rhinosinusitis with nasal polyposis improved after endoscopic surgery, showing longer REM sleep durations.

In COPD, anticipatory nursing, boosted QoL, eased distress, and reduced complications in 6 months.

Nutritional assessment tools in COPD can flag malnutrition early, with MNA in outpatient, PG-SGA inpatient, and NRS-2002 screening.

Obstructive sleep apnea was independently associated with higher odds of nontraumatic fracture history among older adults.

Interviews with UK clinicians found inconsistent terminology and testing gaps that drive variation in preschool wheeze management.

Endoscopic lung volume reduction (ELVR) is increasingly used in COPD with severe hyperinflation, yet sex specific outcome data have been limited.

FT-IR microspectroscopy blood test detected a single circulating tumor cell in one patient with lung cancer, cytospun raw blood sample.

SARS-CoV-2 infection may drive gut dysbiosis that amplifies lung inflammation and rifaximin could help interrupt this axis overall.

Cigarette smoking increased cardiovascular risks at 2–5 cigarettes daily; cessation rapidly lowered risk within ten years, overall.

In this cross-sectional community-based study, investigators assessed whether routine pneumococcal vaccination and rotavirus vaccination influence colonization in children younger than 15.

C3 gene variation may clarify why some lung transplant recipients develop chronic rejection over time.

Global estimates show cytomegalovirus linked lower respiratory infections remain a persistent cause of death worldwide.

Metagenomic profiling of airborne microbial communities is opening new windows on pathogen risks in crowded transport.

Dietary iron deficiency during influenza infection may leave memory T cells numerically intact yet functionally weakened.

Inhalers prescribed for asthma and COPD generated nearly 25 million metric tons of greenhouse gas emissions in the United States over the past decade.

Tezepelumab oral corticosteroid reduction in severe asthma achieved meaningful steroid sparing without loss of asthma control.

New onset interstitial lung disease has intensive care mortality matching established disease in severe respiratory failure.

Age-based lung cancer screening could detect far more cases than current US risk-based eligibility criteria.

Moderate thrombosis in lung injury may paradoxically protect sepsis related ARDS via endothelial ALOX15 driven signaling.

A modified mRNA influenza vaccine delivered superior efficacy with more reactogenicity than a licensed quadrivalent comparator.

Inhaled molgramostim improved gas transfer and quality of life in adults with autoimmune pulmonary alveolar proteinosis.

Updated NCCN Guidelines for non-small cell lung cancer (NSCLC) detail expanded systemic therapy options that strengthen outcomes for patients with resectable and unresectable disease.

An inpatient COPD care pathway embedded in the electronic health record improved rehabilitation referrals and home discharges.

An intranasal bird flu vaccine safely primes broad mucosal and systemic immunity in a Phase I trial.

Lung cancer survival rates are improving nationwide; however, recent funding cuts could threaten continued progress in prevention and treatment.

The new analysis shows that lung function changes across the menopausal transition accelerate several years before menopause and remain elevated thereafter.

A systematic review finds inspiratory muscle training may enhance exercise tolerance in adult patients with post-COVID-19 syndrome.

Device-captured cough droplets detected SARS-CoV-2 RNA and inflammatory biomarkers from the lower respiratory tract in patients.

BMI influences lung performance in children with asthma, with benefits that reverse beyond a critical weight threshold.

A landmark 32.5-year follow-up of a smoking cessation intervention showed enduring reductions in respiratory mortality among U.S. adults who received targeted support to quit smoking.

Stubborn lung infection can evolve within patients and develop traits that help it persist over time.

Patients with type 2 diabetes and obstructive sleep apnea experienced significantly greater survival benefits from GLP-1 receptor agonist therapy than those without sleep apnea.

Inhaled treprostinil treatment improved cardiac effort and physiological function in patients with pulmonary hypertension–interstitial lung disease.

GLP-1 receptor agonists significantly reduced the risk of right heart failure in patients with pulmonary arterial hypertension compared with SGLT2-inhibitors.

Nasal irrigation could provide a practical, non-invasive alternative for monitoring airway microbiology in people with cystic fibrosis.

Ensifentrine improved symptoms, dyspnea, and quality of life in stable COPD without exacerbations in ENHANCE trials.

Alpha-1 antitrypsin deficiency (AATD) remains a frequently underdiagnosed condition that predisposes individuals to chronic lung and liver diseases.

Osimertinib plus chemotherapy improved overall survival versus monotherapy in EGFR-mutated advanced NSCLC in a Phase III trial.

In a Phase III trial, the addition of nerandomilast demonstrated a promising ability to slow disease progression in patients with idiopathic pulmonary fibrosis (IPF).

Nirsevimab administration was linked to lower RSV hospitalization among U.S. infants this season in analysis of real-world data.

Azelastine nasal spray reduced PCR-confirmed SARS-CoV-2 infections versus placebo in a Phase II randomized trial in adults.

Mycoplasma pneumoniae accounts for a meaningful share of community-acquired pneumonia in younger hospitalized adults.

Childhood body size is linked to COPD risk in adulthood, with above-average BMI trajectories associated with higher COPD incidence.

Researchers have developed an innovative taste-based sensor for influenza detection, designed to identify infection through a chemical response on the tongue.

A growing body of evidence suggests that food additives may play a role in the development and exacerbation of childhood asthma.

Distinct gut bacteria may play a role in driving lung damage among people with systemic sclerosis (SSc).

An online group singing program significantly improved quality of life in people with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).

Indoor wood burning is increasingly linked to declining lung function, with new findings suggesting a rising public health threat in Europe.

Early exposure to household dog allergens was associated with a reduced risk of asthma and improved lung function in childhood, according to findings from a large population-based cohort.

Asthma management in women requires tailored approaches across puberty, pregnancy, and menopause, as each life stage introduces unique challenges that influence symptoms, adherence, and outcomes.

Necrotising lung infections (NLI) significantly affect the course and outcomes of patients requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO).

Donor-derived infections are a significant concern for heart and lung transplant recipients, with established and emerging pathogens creating complex challenges for post-transplant care, according to new research.

Machine learning can help predict urgent care visits in patients with non–small cell lung cancer receiving systemic therapy.

Children with sleep-disordered breathing who experience a higher hypoxic burden show stronger links to sleepiness and disease severity, according to new research.

Psychological support combined with respiratory function training has been shown to reduce anxiety a

Biologics directed at type 2 inflammation appear to offer the most promising therapeutic option for patients with eosinophilic chronic obstructive pulmonary disease (COPD), according to a multicriteria decision analysis of clinical trials.

Solid-organ transplant recipients face a markedly higher risk of developing nontuberculous mycobacterial disease compared with the general population, and this risk translates into greater long-term mortality, according to findings from a large population-based cohort study.

Interferon-induced transmembrane protein 3 (IFITM3) has been identified as a critical regulator of immunotherapy response in small cell lung cancer (SCLC), with new findings showing its potential role as both a predictive biomarker and therapeutic target.

A first-in-human trial has demonstrated encouraging clinical activity and manageable safety for the DLL3-targeted antibody-drug conjugate SHR-4849 in patients with relapsed small cell lung cancer (SCLC).

Paternal prepubertal exposure to passive smoke is associated with impaired lung function trajectories in their children, persisting from childhood into middle age and raising the risk of chronic obstructive pulmonary disease (COPD).

Children with asthma face a heightened risk of fractures, particularly when treated with corticosteroids, according to findings from a large nationwide cohort study.

GLP-1 receptor agonists (GLP-1RA) are emerging as a potential therapeutic option for patients with obstructive sleep apnea (OSA), according to a recent review that examined growing clinical evidence.

Telemedicine follow-up significantly improved quality of life and inhaler use techniques among patients with advanced chronic obstructive pulmonary disease (COPD), according to a randomized controlled trial.

Adults with psoriasis may be more likely to also have chronic bronchitis, according to new U.S. population-based findings.