Respiratory

A first-in-human trial has demonstrated encouraging clinical activity and manageable safety for the DLL3-targeted antibody-drug conjugate SHR-4849 in patients with relapsed small cell lung cancer (SCLC).

Paternal prepubertal exposure to passive smoke is associated with impaired lung function trajectories in their children, persisting from childhood into middle age and raising the risk of chronic obstructive pulmonary disease (COPD).

Children with asthma face a heightened risk of fractures, particularly when treated with corticosteroids, according to findings from a large nationwide cohort study.

GLP-1 receptor agonists (GLP-1RA) are emerging as a potential therapeutic option for patients with obstructive sleep apnea (OSA), according to a recent review that examined growing clinical evidence.

Telemedicine follow-up significantly improved quality of life and inhaler use techniques among patients with advanced chronic obstructive pulmonary disease (COPD), according to a randomized controlled trial.

Adults with psoriasis may be more likely to also have chronic bronchitis, according to new U.S. population-based findings.

Severe Legionnaires’ disease requiring intensive care unit (ICU) admission shows improved survival compared to earlier reports, according to a multicenter retrospective cohort study of French patients.

Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is increasingly recognized as a major factor influencing long-term outcomes in affected patients, with new data showing that disease progression and specific lung patterns significantly impact mortality.