Allergy & Immunology

Among the most highly prioritised features were a longer product shelf life and improved storage conditions, both receiving a median importance score of 9.

Functional experiments showed that α-zein–specific Treg cells suppressed naïve T cell proliferation when exposed to the antigen, confirming their role in maintaining oral tolerance.

Functional assays showed that PPIs also reduced fibroblast migration and oxidative stress, both of which contribute to tissue remodelling.

Individuals with higher abundance of common peanut-degrading bacteria, including Rothia, exhibited a higher threshold for allergic reactions during controlled exposure.

Complete response, defined as UAS7=0 at Week 12, was achieved in 22.9% of patients receiving 75 mg, 51.1% receiving 150 mg, and 37.5% receiving 300 mg.

Codfish oral immunotherapy improved desensitisation rates in children with fish allergy, though sustained unresponsiveness remained limited.

The study identified 37 single nucleotide polymorphisms (SNPs) reaching suggestive significance (p

These data suggested that RIPK1 inhibition targeted two central pathological processes in inflammatory skin diseases: epidermal cell death and immune-driven inflammation.