Allergy & Immunology

Importantly, this microbiota–metabolite signature was inversely associated with the development of food allergen-specific IgE up to 5 years of age and with atopic dermatitis at 2 years.

ALA-DAG oil improved skin hydration and reduced allergic symptoms in adults with mild skin discomfort.

After 1 year, 13 of 17 patients in the 30 mg group tolerated at least 443 mg peanut protein, compared with none in the avoidance group. Similar improvements were observed in the 300 mg group.

Autoclaving peanuts significantly reduces IgE binding and improves tolerability in peanut-allergic individuals, offering promise for safer immunotherapy approaches.

The basophil activation test may help identify children at risk of severe allergic reactions to cow’s milk, improving safety during oral food challenges.

A Canadian real-world study reveals high oral corticosteroid exposure in patients with severe chronic rhinosinusitis with nasal polyps prior to biologic therapy.

International panel of anaphylaxis experts develops guidance for non-medical personnel to correctly identify patients with acute allergic reactions that require epinephrine administration.  

High airway TSLP levels identify a subset of severe asthma patients with type 2 inflammation, mucus plugging, and airway remodelling despite corticosteroid treatment.