Allergy & Immunology

Machine learning prediction models identified children with eczema at highest risk of asthma and allergic rhinitis by school age.

A first-in-human trial found inhaled anti-TSLP asthma therapy was well tolerated and reduced airway inflammation. Learn more.

Researchers found that asthma prevalence peaked sharply at age three, affecting 29.0% of children with early AD.

The infant gut microbiome is dynamic and responsive to early-life environmental influences, with sibling exposure emerging as a potentially important factor in shaping microbial development.

Patients who underwent DOC were significantly more likely to receive penicillin at 90 days and less likely to be prescribed World Health Organization “Watch” or “Reserve” antibiotics.

The findings showed that early immune cross-regulation played a decisive role in controlling protease hypersensitivity

Polygenic risk score models derived from variants prioritised by the deep learning framework demonstrated improved predictive performance compared with those based on traditional GWAS approaches.

In a direct comparison, the AI models outperformed 24 clinicians when diagnosing a subset of patients.