Allergy & Immunology

In a small Swiss study, patients with adult-onset egg white allergy exhibited moderate to severe restrictions in daily life.

Dysbiosis, or microbial imbalance, can predispose individuals to allergies, while a balanced gut microbiome fosters immune tolerance.

The trial highlighted that the Zagreb regimen led to fewer doses and a shorter vaccination period, improving compliance and cost-effectiveness.

The trial found increased beneficial gut bacteria such as Lactobacillus and Bifidobacterium, alongside reduced pro-inflammatory species.

A recent study explored the effectiveness of four treatment protocols, including nasal corticosteroids and antihistamines for children with allergic rhinitis.

Between 1990–2010, the number of African children with asthma rose from 34 million to 50 million, driven partly by increased urbanisation.

This variant results in reduced STAT6 protein levels, dampened IL-4 responses, and lower IgE and eosinophil counts in the blood.

The trial included 135 adults, randomly assigned to receive either inebilizumab or a placebo for a 52-week treatment period.