Hematology

Randomised trial shows intravenous iron significantly improves maternal haemoglobin before delivery in non-anaemic iron deficient pregnancy, supporting ferritin screening and targeted treatment in antenatal care.

Daratumumab-lenalidomide maintenance enhances MRD-negative conversion and reduces progression in multiple myeloma patients regardless of age, race, or cytogenetic risk.

An optimised OFA/iLRP aptamer forms a DNA nanostructure delivering doxorubicin selectively to AML cells, improving efficacy and reducing toxicity in preclinical models.

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and thromboinflammation.

At ASH 2025, investigators reported early results from the first-in-human phase 1 inMMyCAR study evaluating KLN-1010, an investigational in vivo gene therapy…

Among patients treated in the first-line setting, the overall response rate was 57.1%, compared with 38.1% in those treated in the second line or later.

The study included 202 adults undergoing cardiac surgery at 11 Australian tertiary hospitals between August 2021 and April 2024.

New genetic evidence suggests that people with an inherited tendency towards blood clots may be at higher risk of developing long COVID.