Hematology

Large-scale data show clonal monocytosis and related conditions predict myeloid neoplasia risk, with improved accuracy using refined diagnostic criteria.

Apixaban significantly reduces bleeding risk compared with rivaroxaban in acute venous thromboembolism, based on data from a large international randomised trial.

A six factor prognostic score predicts survival in CML blast phase, enabling improved risk stratification and comparison across clinical studies.

Physicians specialising in sickle cell disease report higher burnout, driven by reduced recreation and job satisfaction despite similar resilience levels.

Autoantibody expression after paediatric stem cell transplantation reflects immune reconstitution rather than chronic graft versus host disease risk, highlighting alternative biomarkers.

A machine learning approach reveals structural HLA biomarkers linked to graft failure, offering a new strategy for donor selection in transplantation.

CD45RA depleted memory T cell therapy shows encouraging results in treating infections after transplant, with high survival and viral clearance rates in early findings.

Survey data reveal strong support for gene therapy in sickle cell disease, but inconsistent referral practices, limited knowledge, and insurance barriers hinder implementation.