Hematology

The PASS aplastic anaemia diagnostic tool accurately differentiates acquired disease from inherited syndromes, enabling rapid clinical decision making using routine data.

Rapid lymphocyte expansion after CAR-T therapy predicts better survival in lymphoma but increases toxicity risk, highlighting its role as a key biomarker.

Individuals with anaemia showed higher levels of key Alzheimer blood biomarkers at baseline, including phosphorylated tau 217 (p-tau217), neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP).

The model identified several key predictors present at diagnosis, including age, sex, immunoglobulin levels (IgG, IgA, and IgM), platelet count, lymphocyte count, presence of a known secondary cause, and positive direct antiglobulin test results.

New research shows sickle cell disease bias in clinician notes is more closely associated with opioid use than race or chronic pain, highlighting documentation disparities.

Long read sequencing accurately detects structural variants in paediatric leukaemia and identifies additional gene fusions missed by routine testing.

A large screening study finds no strong link between diet and MGUS risk, although high dairy intake may increase the likelihood of IgA MGUS.

Large-scale data show clonal monocytosis and related conditions predict myeloid neoplasia risk, with improved accuracy using refined diagnostic criteria.