Hematology

New research shows sickle cell disease bias in clinician notes is more closely associated with opioid use than race or chronic pain, highlighting documentation disparities.

Long read sequencing accurately detects structural variants in paediatric leukaemia and identifies additional gene fusions missed by routine testing.

A large screening study finds no strong link between diet and MGUS risk, although high dairy intake may increase the likelihood of IgA MGUS.

Large-scale data show clonal monocytosis and related conditions predict myeloid neoplasia risk, with improved accuracy using refined diagnostic criteria.

Apixaban significantly reduces bleeding risk compared with rivaroxaban in acute venous thromboembolism, based on data from a large international randomised trial.

A six factor prognostic score predicts survival in CML blast phase, enabling improved risk stratification and comparison across clinical studies.

Physicians specialising in sickle cell disease report higher burnout, driven by reduced recreation and job satisfaction despite similar resilience levels.

Autoantibody expression after paediatric stem cell transplantation reflects immune reconstitution rather than chronic graft versus host disease risk, highlighting alternative biomarkers.